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The map label for this gene is ydjJ [C]

Identifier: 182679297

GI number: 182679297

Start: 2678198

End: 2679244

Strand: Reverse

Name: ydjJ [C]

Synonym: Bind_2341

Alternate gene names: 182679297

Gene position: 2679244-2678198 (Counterclockwise)

Preceding gene: 182679298

Following gene: 182679296

Centisome position: 64.25

GC content: 60.27

Gene sequence:

>1047_bases
ATGCAAGCTCTCGTTCTCGAGCGCAAGGGCGAATTGTCTCTGCGCGATGTGGACCTGCCCTTGGCGGTCGGGCCGGGCCA
AGTGAAAATCGCGGTCCATACGGTGGGTATCTGCGGCAGCGATGTGCATTATTTCACGCATGGCAGTATTGGGCCCTATA
TCGTTGAAAAACCGATGGTCCTTGGGCATGAGGCGACCGGCACGATCGTCGAAGTCGGACCGAATGTCAGCACTTTAAAG
GTCGGAGACCGGGTCTGTATGGAACCTGGGGTGCCCGACATGTCGTCCCGGGCGTCCAAGCTTGGTCTCTATAATGTAGA
CCCATCCGTGACCTTCTGGGCGACGCCTCCCGTCCATGGTGTGCTGACACCTTATGTCGTTCACCCTGCCGCCTTCACCT
ATAAGTTGCCCGCCAATGTATCCTTCGCGGAAGGCGCTTTGGTCGAGCCCTTCGCGATTGGCATGCAGGCGGCAACGCGG
GCGCGGATCGCTCCGGGCGATGTTGCAGCAGTTATCGGTGCAGGTACGATTGGCATCATGACGGCTCTCGCGGCGGTGGC
TGGCGGCTGCTCGCGCGTCTTCATCTCCGATTTCAGCAAGGAGAAACTGGCGATCGCTGGGGGCTATGATTGCATTGTTC
CCGTCAATGCCGGTGAGGAATCGCTGGCCGACGTCGTCGCCAGGGAGACGGAGAACTGGGGGGCCGACGTTGTGTTCGAG
GCCAGCGGCAGCCCCAAGGCCTATGGCGATCTCTTCCGGATCGTCCGTCCGGGCGGCGCCGTGGTGCTCGTTGGCCTGCC
GGTGGAGCCCGTGGCCTTTGATGTGTCGAGTGCCATTTCCAAGGAAGTGCGGATCGAGACAGTGTTTCGCTACGCCAATA
TTTTCGATCGCGCCTTGGCCCTGATCGCATCCGGCAAGGTCAATCTGAAGCCTCTGATTACAGGCACATTCCCCTTTTCG
GATAGTGTCGTTGCTTTTGAGCGGGCCGCTGCCGGCCGGCCGACGGATGTGAAGCTGCAGATCGAGGTCGTCAGCGAAAA
CGCCTGA

Upstream 100 bases:

>100_bases
AGCATCAATGGCCATCCCCGATCCGAGCGGGATGATGAAAAGCCAAGCCATTGAATTTTTGAAGAATTACTGGCGTTGCG
GCCGGTGAGGGGAGGAACTC

Downstream 100 bases:

>100_bases
CACTTTTAGTTGTCGCATGCTCCTTTCAGGAACGACTGCTGGCTTTGTCTCGGCAGGCGATGGAAGGAGTGCGTCCATCG
AACACGAAGGAAAGCAAAAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQALVLERKGELSLRDVDLPLAVGPGQVKIAVHTVGICGSDVHYFTHGSIGPYIVEKPMVLGHEATGTIVEVGPNVSTLK
VGDRVCMEPGVPDMSSRASKLGLYNVDPSVTFWATPPVHGVLTPYVVHPAAFTYKLPANVSFAEGALVEPFAIGMQAATR
ARIAPGDVAAVIGAGTIGIMTALAAVAGGCSRVFISDFSKEKLAIAGGYDCIVPVNAGEESLADVVARETENWGADVVFE
ASGSPKAYGDLFRIVRPGGAVVLVGLPVEPVAFDVSSAISKEVRIETVFRYANIFDRALALIASGKVNLKPLITGTFPFS
DSVVAFERAAAGRPTDVKLQIEVVSENA

Sequences:

>Translated_348_residues
MQALVLERKGELSLRDVDLPLAVGPGQVKIAVHTVGICGSDVHYFTHGSIGPYIVEKPMVLGHEATGTIVEVGPNVSTLK
VGDRVCMEPGVPDMSSRASKLGLYNVDPSVTFWATPPVHGVLTPYVVHPAAFTYKLPANVSFAEGALVEPFAIGMQAATR
ARIAPGDVAAVIGAGTIGIMTALAAVAGGCSRVFISDFSKEKLAIAGGYDCIVPVNAGEESLADVVARETENWGADVVFE
ASGSPKAYGDLFRIVRPGGAVVLVGLPVEPVAFDVSSAISKEVRIETVFRYANIFDRALALIASGKVNLKPLITGTFPFS
DSVVAFERAAAGRPTDVKLQIEVVSENA
>Mature_348_residues
MQALVLERKGELSLRDVDLPLAVGPGQVKIAVHTVGICGSDVHYFTHGSIGPYIVEKPMVLGHEATGTIVEVGPNVSTLK
VGDRVCMEPGVPDMSSRASKLGLYNVDPSVTFWATPPVHGVLTPYVVHPAAFTYKLPANVSFAEGALVEPFAIGMQAATR
ARIAPGDVAAVIGAGTIGIMTALAAVAGGCSRVFISDFSKEKLAIAGGYDCIVPVNAGEESLADVVARETENWGADVVFE
ASGSPKAYGDLFRIVRPGGAVVLVGLPVEPVAFDVSSAISKEVRIETVFRYANIFDRALALIASGKVNLKPLITGTFPFS
DSVVAFERAAAGRPTDVKLQIEVVSENA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=349, Percent_Identity=40.6876790830946, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=25.8152173913043, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788073, Length=341, Percent_Identity=38.41642228739, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1790045, Length=346, Percent_Identity=29.7687861271676, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1790718, Length=319, Percent_Identity=28.2131661442006, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI226510992, Length=341, Percent_Identity=31.6715542521994, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787863, Length=336, Percent_Identity=27.3809523809524, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788407, Length=343, Percent_Identity=26.530612244898, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788075, Length=342, Percent_Identity=26.6081871345029, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082125, Length=350, Percent_Identity=25.4285714285714, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=334, Percent_Identity=40.4191616766467, Blast_Score=255, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17562878, Length=312, Percent_Identity=41.025641025641, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=40.6340057636888, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322619, Length=332, Percent_Identity=39.4578313253012, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319955, Length=332, Percent_Identity=39.4578313253012, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319257, Length=272, Percent_Identity=30.8823529411765, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=382, Percent_Identity=23.8219895287958, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=292, Percent_Identity=29.4520547945205, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=308, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17137530, Length=325, Percent_Identity=39.3846153846154, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17737897, Length=342, Percent_Identity=38.8888888888889, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI221457811, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI45550770, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI45551930, Length=306, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 36386; Mature: 36386

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALVLERKGELSLRDVDLPLAVGPGQVKIAVHTVGICGSDVHYFTHGSIGPYIVEKPMV
CCEEEEECCCCCEEEECCCEEEECCCEEEEEEEEEEECCCCEEEEECCCCCCEEEECCEE
LGHEATGTIVEVGPNVSTLKVGDRVCMEPGVPDMSSRASKLGLYNVDPSVTFWATPPVHG
ECCCCCCEEEEECCCEEEEEECCEEECCCCCCCHHHHHHHCCEEECCCCEEEEECCCCCC
VLTPYVVHPAAFTYKLPANVSFAEGALVEPFAIGMQAATRARIAPGDVAAVIGAGTIGIM
CCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHH
TALAAVAGGCSRVFISDFSKEKLAIAGGYDCIVPVNAGEESLADVVARETENWGADVVFE
HHHHHHHCCCCEEEEECCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEE
ASGSPKAYGDLFRIVRPGGAVVLVGLPVEPVAFDVSSAISKEVRIETVFRYANIFDRALA
CCCCCCHHHHHHHEECCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LIASGKVNLKPLITGTFPFSDSVVAFERAAAGRPTDVKLQIEVVSENA
HHHCCCCEEEEEEEEECCCCCCEEEEHHHCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MQALVLERKGELSLRDVDLPLAVGPGQVKIAVHTVGICGSDVHYFTHGSIGPYIVEKPMV
CCEEEEECCCCCEEEECCCEEEECCCEEEEEEEEEEECCCCEEEEECCCCCCEEEECCEE
LGHEATGTIVEVGPNVSTLKVGDRVCMEPGVPDMSSRASKLGLYNVDPSVTFWATPPVHG
ECCCCCCEEEEECCCEEEEEECCEEECCCCCCCHHHHHHHCCEEECCCCEEEEECCCCCC
VLTPYVVHPAAFTYKLPANVSFAEGALVEPFAIGMQAATRARIAPGDVAAVIGAGTIGIM
CCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHH
TALAAVAGGCSRVFISDFSKEKLAIAGGYDCIVPVNAGEESLADVVARETENWGADVVFE
HHHHHHHCCCCEEEEECCCCCEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEE
ASGSPKAYGDLFRIVRPGGAVVLVGLPVEPVAFDVSSAISKEVRIETVFRYANIFDRALA
CCCCCCHHHHHHHEECCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
LIASGKVNLKPLITGTFPFSDSVVAFERAAAGRPTDVKLQIEVVSENA
HHHCCCCEEEEEEEEECCCCCCEEEEHHHCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]