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The map label for this gene is thrB

Identifier: 182679290

GI number: 182679290

Start: 2670603

End: 2671568

Strand: Reverse

Name: thrB

Synonym: Bind_2334

Alternate gene names: 182679290

Gene position: 2671568-2670603 (Counterclockwise)

Preceding gene: 182679291

Following gene: 182679289

Centisome position: 64.06

GC content: 60.56

Gene sequence:

>966_bases
ATGGCCGTTTACACACATATCTCGGAAACGGATCTCAAAACCTTCCTCGCCTCCTACGACATCGGCAATGCTCTGGTGCT
TAAGGGCATTGCCGAAGGTGTCGAAAATTCCAATTTCTTCCTCCAGACGGAGAGAGGCTTCTTCATCCTCACCCTTTACG
AGAAGAGGGTGGAGGAAAAGGATCTGCCGTTCTTCCTGGGGTTGATGGAACATCTCTCCCGGCGTGGCTTGAATTGTCCG
CAGCCGGTGCACAACCGCTCGGGCCACGCGCTGGGTCGGCTCGCGGGACGGCCTGCCGTCATCGTCACATTCCTCGAAGG
CGTTGGCGCCGATGTGGCGGATGCCAGGCGCTGCGCCGCCGTAGGAGAGGCGCTGGCGCGCCTGCATCAGGCCGGCGCCG
ATTTTGCCGGAAAACGTACCAATGCCCTGGGGCTTGCCGCCTGGCGCCCGCTTTTCGAGACTGTGCGGGACAGGGCCGAT
ACGGTCGCCCCGGCGCTTGCGGCGACCATTGCCGAGGAACTCGATTTTCTCGAAGCCCACTGGCCACGCGCCTTGCCGCA
GGGCGTCATTCATGCCGATCTCTTCCCTGACAATGTTCTGTTTCGGGGCGAGACCCTGTCTGGTTTGATCGACTTTTACT
TCGCCTGCGTCGATGCCTATGCCTACGATATTGCGATCTGTCTCAATGCCTGGTGTTTTGAGCCGGATCTGACGTTCAAT
ATTGGCAAGGGGCTCGCTTTCTTCACGGGCTATGAGCATGTGCGCAAGCTGACCGCCGAAGAGGCGGCCGCTTTGCCGGT
GCTGGCGCGCGGCGGCGCTTTGCGCTTCGCCTTGACCCGCCTCGTCGATTGGCTGAACGTGCCAAAGGGCGCCATGGTGA
ATCCCAAGGACCCGCTGGAATATATGGGCAAGCTGGCCTTTCACCAGACCGTGGGGACCGTGCGCGAGCTGGGATTGTTG
CGATGA

Upstream 100 bases:

>100_bases
GCATGTGAATCTCTCGCAAAAAGACTATTGGGAATGGGATCCGATGCTATAGAGCCGGTCTGCCCAAACATTCCTACGCC
CCGCGGGATTTCCTGACGCA

Downstream 100 bases:

>100_bases
GCGGGCGTGTCACGATCTACACCGACGGCGCCTGTTCCGGTAATCCAGGGCCCGGCGGCTGGGGCGCCATTTTGATGTTT
GGACAGCATGAAAAGGAACT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTHISETDLKTFLASYDIGNALVLKGIAEGVENSNFFLQTERGFFILTLYEKRVEEKDLPFFLGLMEHLSRRGLNCP
QPVHNRSGHALGRLAGRPAVIVTFLEGVGADVADARRCAAVGEALARLHQAGADFAGKRTNALGLAAWRPLFETVRDRAD
TVAPALAATIAEELDFLEAHWPRALPQGVIHADLFPDNVLFRGETLSGLIDFYFACVDAYAYDIAICLNAWCFEPDLTFN
IGKGLAFFTGYEHVRKLTAEEAAALPVLARGGALRFALTRLVDWLNVPKGAMVNPKDPLEYMGKLAFHQTVGTVRELGLL
R

Sequences:

>Translated_321_residues
MAVYTHISETDLKTFLASYDIGNALVLKGIAEGVENSNFFLQTERGFFILTLYEKRVEEKDLPFFLGLMEHLSRRGLNCP
QPVHNRSGHALGRLAGRPAVIVTFLEGVGADVADARRCAAVGEALARLHQAGADFAGKRTNALGLAAWRPLFETVRDRAD
TVAPALAATIAEELDFLEAHWPRALPQGVIHADLFPDNVLFRGETLSGLIDFYFACVDAYAYDIAICLNAWCFEPDLTFN
IGKGLAFFTGYEHVRKLTAEEAAALPVLARGGALRFALTRLVDWLNVPKGAMVNPKDPLEYMGKLAFHQTVGTVRELGLL
R
>Mature_320_residues
AVYTHISETDLKTFLASYDIGNALVLKGIAEGVENSNFFLQTERGFFILTLYEKRVEEKDLPFFLGLMEHLSRRGLNCPQ
PVHNRSGHALGRLAGRPAVIVTFLEGVGADVADARRCAAVGEALARLHQAGADFAGKRTNALGLAAWRPLFETVRDRADT
VAPALAATIAEELDFLEAHWPRALPQGVIHADLFPDNVLFRGETLSGLIDFYFACVDAYAYDIAICLNAWCFEPDLTFNI
GKGLAFFTGYEHVRKLTAEEAAALPVLARGGALRFALTRLVDWLNVPKGAMVNPKDPLEYMGKLAFHQTVGTVRELGLLR

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_BEII9 (B2IHG2)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833436.1
- ProteinModelPortal:   B2IHG2
- GeneID:   6198647
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_2334
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   CLSK2405699
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 35276; Mature: 35145

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTHISETDLKTFLASYDIGNALVLKGIAEGVENSNFFLQTERGFFILTLYEKRVEEK
CEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHCCCC
DLPFFLGLMEHLSRRGLNCPQPVHNRSGHALGRLAGRPAVIVTFLEGVGADVADARRCAA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHEEEEHHHCCCCHHHHHHHHH
VGEALARLHQAGADFAGKRTNALGLAAWRPLFETVRDRADTVAPALAATIAEELDFLEAH
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPRALPQGVIHADLFPDNVLFRGETLSGLIDFYFACVDAYAYDIAICLNAWCFEPDLTFN
CCHHHHCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IGKGLAFFTGYEHVRKLTAEEAAALPVLARGGALRFALTRLVDWLNVPKGAMVNPKDPLE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YMGKLAFHQTVGTVRELGLLR
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVYTHISETDLKTFLASYDIGNALVLKGIAEGVENSNFFLQTERGFFILTLYEKRVEEK
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHCCCC
DLPFFLGLMEHLSRRGLNCPQPVHNRSGHALGRLAGRPAVIVTFLEGVGADVADARRCAA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHEEEEHHHCCCCHHHHHHHHH
VGEALARLHQAGADFAGKRTNALGLAAWRPLFETVRDRADTVAPALAATIAEELDFLEAH
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPRALPQGVIHADLFPDNVLFRGETLSGLIDFYFACVDAYAYDIAICLNAWCFEPDLTFN
CCHHHHCCCEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IGKGLAFFTGYEHVRKLTAEEAAALPVLARGGALRFALTRLVDWLNVPKGAMVNPKDPLE
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YMGKLAFHQTVGTVRELGLLR
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA