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The map label for this gene is ltrA [H]

Identifier: 182679053

GI number: 182679053

Start: 2388506

End: 2389429

Strand: Direct

Name: ltrA [H]

Synonym: Bind_2089

Alternate gene names: 182679053

Gene position: 2388506-2389429 (Clockwise)

Preceding gene: 182679051

Following gene: 182679054

Centisome position: 57.28

GC content: 59.63

Gene sequence:

>924_bases
ATGGATCGCATCGATGCGATGAAAGTCTTCGTCGCCGCGCTCGATGAAGGCAGTCTCGCCGGCGCGGGGCGTCGTCTTGG
GCGTTCACCGGCCGCCGTCAGTCGCGCTGTCGCCTTTCTCGAAGACCATGTCGGCGTGCAACTCCTCCATCGAACAACGC
GCTCGATTAAATTGAGCGAGGCGGGCGAACGCTATGCCGCCGCCTGCCGCCGTGTGCTAACCGATCTCGAGGAGGCCGAT
ATTCTCGCCGTCGGCGAGCGCTCGGCGCCGCGTGGAACGCTGACCATTACAGCGCCGGTCATCAGCGGCGAGGATATCCT
AAGGCCGATCCTCGACGCTTTTCTCGATGCCTACCCCACCGTTTCAGCCAAACTCTATCTGCTTGATCGGCCGGTCAATC
TGATTGATGAGGGAGTCGATGTCGCTTTGCGTATCGCGCACCTTCCCGACTCATCAATGGTCGCGACCCGCGTCGGCGAA
GTCCGGCGCATTATTGTCGCCTCTCCTCGCTATCTCACCGAACATCCACGCATCCTGGAGCCCAGCGATCTCGCTAAACA
CCAGATCATCGCCATGACGCATTTCGGGCTGGACTCCTGGAGTTTTCCGCCTATGGAAGGCTCGACCATTCCCCGTAGCG
TTTCCTTCACGCCACGCTTCATCGTCAATAGTGTGCGGGCAGCAGTCGCCTCCGCCGCCGAAGGCCATGGCGTCACACGA
CTGTTTTCCTATCATGTCGCGGAAAAGGTCCGGGAAGGCCAATTACTGATTATCTTGAGCGATACCGAACACACATCCTT
GCCGGTCCATGTCATCACGCAGGAAGGCAGGCTTTCTGTTCCGAAAGTTCGTGCTTTCGTGGATTTTGCCGTGCCACGCC
TGCGCAAGCACTTTGGCCGCCTGACCACCGACACCAAGGGCTGA

Upstream 100 bases:

>100_bases
TCATCGACGCGTATCATCATGCCTTCTTGTGATATAGCCTTGCGTATTCCGGCAGAATATTTAGAGTTCGGCAGTCAGTA
TTCCAACTTTCGGAAGAATT

Downstream 100 bases:

>100_bases
TCTTTCATTCACTCGTTTTACGGAAGAGTTTCTGCCGAATAGCGCCTATTCGATCGCAAAAGATCAAACATAAATGATTT
GTGCCGGCTCTGAACAGGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDRIDAMKVFVAALDEGSLAGAGRRLGRSPAAVSRAVAFLEDHVGVQLLHRTTRSIKLSEAGERYAAACRRVLTDLEEAD
ILAVGERSAPRGTLTITAPVISGEDILRPILDAFLDAYPTVSAKLYLLDRPVNLIDEGVDVALRIAHLPDSSMVATRVGE
VRRIIVASPRYLTEHPRILEPSDLAKHQIIAMTHFGLDSWSFPPMEGSTIPRSVSFTPRFIVNSVRAAVASAAEGHGVTR
LFSYHVAEKVREGQLLIILSDTEHTSLPVHVITQEGRLSVPKVRAFVDFAVPRLRKHFGRLTTDTKG

Sequences:

>Translated_307_residues
MDRIDAMKVFVAALDEGSLAGAGRRLGRSPAAVSRAVAFLEDHVGVQLLHRTTRSIKLSEAGERYAAACRRVLTDLEEAD
ILAVGERSAPRGTLTITAPVISGEDILRPILDAFLDAYPTVSAKLYLLDRPVNLIDEGVDVALRIAHLPDSSMVATRVGE
VRRIIVASPRYLTEHPRILEPSDLAKHQIIAMTHFGLDSWSFPPMEGSTIPRSVSFTPRFIVNSVRAAVASAAEGHGVTR
LFSYHVAEKVREGQLLIILSDTEHTSLPVHVITQEGRLSVPKVRAFVDFAVPRLRKHFGRLTTDTKG
>Mature_307_residues
MDRIDAMKVFVAALDEGSLAGAGRRLGRSPAAVSRAVAFLEDHVGVQLLHRTTRSIKLSEAGERYAAACRRVLTDLEEAD
ILAVGERSAPRGTLTITAPVISGEDILRPILDAFLDAYPTVSAKLYLLDRPVNLIDEGVDVALRIAHLPDSSMVATRVGE
VRRIIVASPRYLTEHPRILEPSDLAKHQIIAMTHFGLDSWSFPPMEGSTIPRSVSFTPRFIVNSVRAAVASAAEGHGVTR
LFSYHVAEKVREGQLLIILSDTEHTSLPVHVITQEGRLSVPKVRAFVDFAVPRLRKHFGRLTTDTKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=30.3135888501742, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=278, Percent_Identity=29.4964028776978, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=28.2392026578073, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=27.6666666666667, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=24.1721854304636, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=25.4355400696864, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787589, Length=262, Percent_Identity=27.4809160305344, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789173, Length=290, Percent_Identity=24.4827586206897, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=292, Percent_Identity=26.3698630136986, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790011, Length=249, Percent_Identity=26.5060240963855, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33575; Mature: 33575

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIDAMKVFVAALDEGSLAGAGRRLGRSPAAVSRAVAFLEDHVGVQLLHRTTRSIKLSE
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHH
AGERYAAACRRVLTDLEEADILAVGERSAPRGTLTITAPVISGEDILRPILDAFLDAYPT
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
VSAKLYLLDRPVNLIDEGVDVALRIAHLPDSSMVATRVGEVRRIIVASPRYLTEHPRILE
CCEEEEEEECCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHEEEEECCHHHCCCCCCCC
PSDLAKHQIIAMTHFGLDSWSFPPMEGSTIPRSVSFTPRFIVNSVRAAVASAAEGHGVTR
CCHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LFSYHVAEKVREGQLLIILSDTEHTSLPVHVITQEGRLSVPKVRAFVDFAVPRLRKHFGR
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LTTDTKG
CCCCCCC
>Mature Secondary Structure
MDRIDAMKVFVAALDEGSLAGAGRRLGRSPAAVSRAVAFLEDHVGVQLLHRTTRSIKLSE
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHH
AGERYAAACRRVLTDLEEADILAVGERSAPRGTLTITAPVISGEDILRPILDAFLDAYPT
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
VSAKLYLLDRPVNLIDEGVDVALRIAHLPDSSMVATRVGEVRRIIVASPRYLTEHPRILE
CCEEEEEEECCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHEEEEECCHHHCCCCCCCC
PSDLAKHQIIAMTHFGLDSWSFPPMEGSTIPRSVSFTPRFIVNSVRAAVASAAEGHGVTR
CCHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LFSYHVAEKVREGQLLIILSDTEHTSLPVHVITQEGRLSVPKVRAFVDFAVPRLRKHFGR
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LTTDTKG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]