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The map label for this gene is ttuB [H]

Identifier: 182679048

GI number: 182679048

Start: 2382856

End: 2384169

Strand: Direct

Name: ttuB [H]

Synonym: Bind_2084

Alternate gene names: 182679048

Gene position: 2382856-2384169 (Clockwise)

Preceding gene: 182679045

Following gene: 182679049

Centisome position: 57.14

GC content: 54.49

Gene sequence:

>1314_bases
ATGAGCATGGAAATGCATGCATTGCCGCTTGCGGCATCCAACAATGTGGATGCTGAAAGCCAGGCCTATCGCAAAGTCTT
CTGGCGCATCGTCCCTTTTCTCATGGTGTGTTACGTGGTCGCCTATCTCGACCGCATCAATGTCGGTTTCGCGAAATTGC
AGATGGCGCAAGACCTGCAATTCAGTGAAGCCGTTTACGGATTAGGGGCCGGAATTTTCTTTCTCGGTTATTTTCTGTTC
GAGATTCCGAGCAATTTGATCCTTCACAAGGTCGGCGCCCGCGTCTGGATCGCGCGGATCATGGTGACCTGGGGTCTGAT
TTCCGCCGCCTTTATCTTTGTTGGCTCGGCGCCAGCCTTTTATGTGATGCGCTTTCTCCTCGGCATGGCGGAAGCAGGTT
TCTACCCAGGTATCATTCTCTATCTGACCTTCTGGTATCCGTCCTATAAACGCGCCAAGATCATCGCCATCTTCATGGCG
GCCATTCCCGTCTCTGGCATTTTCGGCAATCCGCTTTCCGGCTGGATCATGGACCAGTTCCATCATACCGGCGGGCTTGC
AGGTTGGCAGTGGATGTTCCTGATCGAAGCGGTCCCCGCTGTCATCGTCGGCATCATCACCTATTTCTATCTCGACAATA
ATATCCGCGATGCCAAATGGCTCAGCGACGACGAAAAGCAGATCCTCGAACAGAATATCAAGGCGCAAGCCGCTCAGCGG
GAAACAACGCATTCGCTCAGGCAGGTCTTCACCAATCCGCGCATCTGGCAAATGGCCTTCATTTATTTTGCCGTCGTGAC
AGGTCAATACGGTTTGACATTCTGGATGCCGACCTTCGTCAAAACTGTGGGTGTGACCGGGAATTTCAATATTGGCCTCA
TTAGCGCGATCCCGTTCCTGTGCGCGGTCGTGGTCATGATCGCCTTTGGCCGCAGCGCCGATCACTATCGTGAACGCCGT
TGGCATCTCGCCATCCCCGCCTTGCTCGGCGCCGTCGGTTTCATCGCCGCAGCAACAACCACCAATATGGGCTTTGCCAT
TCTCTTTTTGTCCTTGGCAGCCGCCGGCGCCCTAACATGCGCCCCCTTGTTCTGGTCACTGCCGACAGCTTTTCTTTCGG
GAACAGCCGCGGCAGGCGGTATCGCCATGATCAATTCCATCGGCAATCTTGCGGGTTTCGTCAGCCCCTATGTCATTGGA
ATGATCCGCGACGCGACGGGCAATACGCAATACGCCATGTATACGCTCGCTGCCATGCTCGTCCTTGGGGCTATCGTCAC
ACTTTTGACACCCGCCAGATTGGTCAATCACTGA

Upstream 100 bases:

>100_bases
TCAATAACAAGAGTTTCCGCGTGATCTCGCTGATCGCGAAAGGGACCCCCCTGAAAACAATCAAGGAAAACCAAGCCCGA
AGCGGGCGAGGGAGGAAAAT

Downstream 100 bases:

>100_bases
GACCAAGGGTGGATCCGGCTCTGAATCCACCCGATCTCAGACATTTTCACCAATCATTTCACGGCCTCTTCGACAATGAA
GGAAAAATAGAATGAATGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSMEMHALPLAASNNVDAESQAYRKVFWRIVPFLMVCYVVAYLDRINVGFAKLQMAQDLQFSEAVYGLGAGIFFLGYFLF
EIPSNLILHKVGARVWIARIMVTWGLISAAFIFVGSAPAFYVMRFLLGMAEAGFYPGIILYLTFWYPSYKRAKIIAIFMA
AIPVSGIFGNPLSGWIMDQFHHTGGLAGWQWMFLIEAVPAVIVGIITYFYLDNNIRDAKWLSDDEKQILEQNIKAQAAQR
ETTHSLRQVFTNPRIWQMAFIYFAVVTGQYGLTFWMPTFVKTVGVTGNFNIGLISAIPFLCAVVVMIAFGRSADHYRERR
WHLAIPALLGAVGFIAAATTTNMGFAILFLSLAAAGALTCAPLFWSLPTAFLSGTAAAGGIAMINSIGNLAGFVSPYVIG
MIRDATGNTQYAMYTLAAMLVLGAIVTLLTPARLVNH

Sequences:

>Translated_437_residues
MSMEMHALPLAASNNVDAESQAYRKVFWRIVPFLMVCYVVAYLDRINVGFAKLQMAQDLQFSEAVYGLGAGIFFLGYFLF
EIPSNLILHKVGARVWIARIMVTWGLISAAFIFVGSAPAFYVMRFLLGMAEAGFYPGIILYLTFWYPSYKRAKIIAIFMA
AIPVSGIFGNPLSGWIMDQFHHTGGLAGWQWMFLIEAVPAVIVGIITYFYLDNNIRDAKWLSDDEKQILEQNIKAQAAQR
ETTHSLRQVFTNPRIWQMAFIYFAVVTGQYGLTFWMPTFVKTVGVTGNFNIGLISAIPFLCAVVVMIAFGRSADHYRERR
WHLAIPALLGAVGFIAAATTTNMGFAILFLSLAAAGALTCAPLFWSLPTAFLSGTAAAGGIAMINSIGNLAGFVSPYVIG
MIRDATGNTQYAMYTLAAMLVLGAIVTLLTPARLVNH
>Mature_436_residues
SMEMHALPLAASNNVDAESQAYRKVFWRIVPFLMVCYVVAYLDRINVGFAKLQMAQDLQFSEAVYGLGAGIFFLGYFLFE
IPSNLILHKVGARVWIARIMVTWGLISAAFIFVGSAPAFYVMRFLLGMAEAGFYPGIILYLTFWYPSYKRAKIIAIFMAA
IPVSGIFGNPLSGWIMDQFHHTGGLAGWQWMFLIEAVPAVIVGIITYFYLDNNIRDAKWLSDDEKQILEQNIKAQAAQRE
TTHSLRQVFTNPRIWQMAFIYFAVVTGQYGLTFWMPTFVKTVGVTGNFNIGLISAIPFLCAVVVMIAFGRSADHYRERRW
HLAIPALLGAVGFIAAATTTNMGFAILFLSLAAAGALTCAPLFWSLPTAFLSGTAAAGGIAMINSIGNLAGFVSPYVIGM
IRDATGNTQYAMYTLAAMLVLGAIVTLLTPARLVNH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=396, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21322234, Length=426, Percent_Identity=24.4131455399061, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=399, Percent_Identity=36.8421052631579, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1789515, Length=412, Percent_Identity=24.7572815533981, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082320, Length=434, Percent_Identity=24.1935483870968, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367379, Length=415, Percent_Identity=23.1325301204819, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=23.1818181818182, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17554962, Length=318, Percent_Identity=23.2704402515723, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=255, Percent_Identity=23.1372549019608, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=338, Percent_Identity=25.1479289940828, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322025, Length=196, Percent_Identity=30.1020408163265, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=318, Percent_Identity=23.2704402515723, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323032, Length=394, Percent_Identity=23.0964467005076, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=166, Percent_Identity=25.3012048192771, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=249, Percent_Identity=22.8915662650602, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321502, Length=403, Percent_Identity=22.3325062034739, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=253, Percent_Identity=22.5296442687747, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=21.978021978022, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641682, Length=389, Percent_Identity=24.1645244215938, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639764, Length=432, Percent_Identity=23.8425925925926, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20130167, Length=402, Percent_Identity=20.8955223880597, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583789, Length=376, Percent_Identity=21.2765957446809, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48146; Mature: 48015

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCHHHHHCC
>Mature Secondary Structure 
SMEMHALPLAASNNVDAESQAYRKVFWRIVPFLMVCYVVAYLDRINVGFAKLQMAQDLQ
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCH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HHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]