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The map label for this gene is ttuB [H]

Identifier: 182679045

GI number: 182679045

Start: 2379472

End: 2380785

Strand: Direct

Name: ttuB [H]

Synonym: Bind_2081

Alternate gene names: 182679045

Gene position: 2379472-2380785 (Clockwise)

Preceding gene: 182679044

Following gene: 182679048

Centisome position: 57.06

GC content: 55.71

Gene sequence:

>1314_bases
ATGTCTCTATCGGTCACCGCGTTTGTCGCGGATTCAGAGGAGAAAAAGGTTGAAGATGCCATCTATCGCAAGGTGACCTG
GCACATTCTTCCCCTCCTCTTTCTTTGCTATCTTTGCGCTTATCTCGATCGTGTGAATGTCGGTCTCGCCAAACTGCAAA
TGTCCGCCGACTTGCAGTTCAGTGAAACGGTTTATGGTCTTGGCGCCGGCATTTTCTTCATCGGCTTCTTCACGGTCGAA
ATTCCCAGCAATATCCTGCTTCACAAACTCGGCGCGCGCGTCTGGATCGCGCGCATCATGATCTCCTGGGGTCTGATTTC
AGGCGCCACCATGTTTGTCACCACGCCTTGGGCCTTCTATGTGCTGCGCTTCTTCCTCGGCGTCGCAGAGGCCGGGTTCT
ATCCCGGCGTCATCCTCTATCTGACTTATTGGTACCCGAAAGAGCGGCGTGGCCGGATTTACGCCCTTTTCGCGACGGCC
GTGCCCTTCTCCGGCATTATTGGCGGTCCCTTGTCCGGCCTGATCATCGATGGCATGAACGGCGTGGCCGGCTGGACCGG
CTGGCAATGGATGTTCCTTTTGGAAGCCTTGCCGTCCATCGTAATGGGCATTGCCGCATTTATTTTCCTTACCGATCATA
TTCATAAAGCCAAATGGCTGTCCGATGCCGAAAAGACGCTTCTGAGCCGGAATATTTCGCGTGATGCGGACGGCAAAACT
GTGCATTCGGTTTGGGCTGCACTGATGAACCGTAAAGTCTGGTTCATGACAACAATCTATTTTTGTCTCATCATGGGATT
TTATGGAGTGGGTTTCTGGCTGCCCACACTCATCAATGCCACCGGCGTCAAAAGCGCTTGGCATGTCGGCTTGCTCACCG
CCATTCCCTATGCATCCGCCGGTATCGCCATGCTGCTCATCGCCCGCAGCGCCGATCGCAGAAACGAACGGCGCTGGCAC
CTCGCGCTGACCTGCGTCGTCGGCGGCATTGGTCTCATCCTCAGCGCGCTTCTATCGCAGAGTATTCCCCTGGCCATGGC
GGGATTGACGCTCGGCGCCATGGGCGCTCTGTCGACACTCCCCTTGTTCTGGAGCATTCCGACAGCTTTCCTGAACGGCA
CAGCCGCAGCGGCCGGCATTGCCTTCATCAATTCAGTCGGTAATCTCGGCGGTTTCGTCAGCCCCTATATGATCGGCTTT
ATCCGCGACACCACGGAAAGTTCCAATTTGGGCATGTATATGCTCGCCGCTTTCCTCTTTCTCGGTGCCGGCCTCACTCT
CCTGGTTCCTGCCAAACTGACCGGCAAAGCGTGA

Upstream 100 bases:

>100_bases
ACCATAAAAATCAATGAGATCGGCGTATCAACCGATCCTGCCGCGCACCATTGTCATGTGGGGTGCTGTCAAAAATACAG
AATACCCGGAGGAAACATCC

Downstream 100 bases:

>100_bases
CGATTAGAGCCACAGTCCCTGGACCGCATTCAATGTGAATGCGGCAAGACGTAATAAATGAACCGCATTCAATGTGAATG
CGGTTCCTCGGCCAATTTCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSLSVTAFVADSEEKKVEDAIYRKVTWHILPLLFLCYLCAYLDRVNVGLAKLQMSADLQFSETVYGLGAGIFFIGFFTVE
IPSNILLHKLGARVWIARIMISWGLISGATMFVTTPWAFYVLRFFLGVAEAGFYPGVILYLTYWYPKERRGRIYALFATA
VPFSGIIGGPLSGLIIDGMNGVAGWTGWQWMFLLEALPSIVMGIAAFIFLTDHIHKAKWLSDAEKTLLSRNISRDADGKT
VHSVWAALMNRKVWFMTTIYFCLIMGFYGVGFWLPTLINATGVKSAWHVGLLTAIPYASAGIAMLLIARSADRRNERRWH
LALTCVVGGIGLILSALLSQSIPLAMAGLTLGAMGALSTLPLFWSIPTAFLNGTAAAAGIAFINSVGNLGGFVSPYMIGF
IRDTTESSNLGMYMLAAFLFLGAGLTLLVPAKLTGKA

Sequences:

>Translated_437_residues
MSLSVTAFVADSEEKKVEDAIYRKVTWHILPLLFLCYLCAYLDRVNVGLAKLQMSADLQFSETVYGLGAGIFFIGFFTVE
IPSNILLHKLGARVWIARIMISWGLISGATMFVTTPWAFYVLRFFLGVAEAGFYPGVILYLTYWYPKERRGRIYALFATA
VPFSGIIGGPLSGLIIDGMNGVAGWTGWQWMFLLEALPSIVMGIAAFIFLTDHIHKAKWLSDAEKTLLSRNISRDADGKT
VHSVWAALMNRKVWFMTTIYFCLIMGFYGVGFWLPTLINATGVKSAWHVGLLTAIPYASAGIAMLLIARSADRRNERRWH
LALTCVVGGIGLILSALLSQSIPLAMAGLTLGAMGALSTLPLFWSIPTAFLNGTAAAAGIAFINSVGNLGGFVSPYMIGF
IRDTTESSNLGMYMLAAFLFLGAGLTLLVPAKLTGKA
>Mature_436_residues
SLSVTAFVADSEEKKVEDAIYRKVTWHILPLLFLCYLCAYLDRVNVGLAKLQMSADLQFSETVYGLGAGIFFIGFFTVEI
PSNILLHKLGARVWIARIMISWGLISGATMFVTTPWAFYVLRFFLGVAEAGFYPGVILYLTYWYPKERRGRIYALFATAV
PFSGIIGGPLSGLIIDGMNGVAGWTGWQWMFLLEALPSIVMGIAAFIFLTDHIHKAKWLSDAEKTLLSRNISRDADGKTV
HSVWAALMNRKVWFMTTIYFCLIMGFYGVGFWLPTLINATGVKSAWHVGLLTAIPYASAGIAMLLIARSADRRNERRWHL
ALTCVVGGIGLILSALLSQSIPLAMAGLTLGAMGALSTLPLFWSIPTAFLNGTAAAAGIAFINSVGNLGGFVSPYMIGFI
RDTTESSNLGMYMLAAFLFLGAGLTLLVPAKLTGKA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=406, Percent_Identity=37.6847290640394, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367379, Length=421, Percent_Identity=23.5154394299287, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789515, Length=465, Percent_Identity=23.8709677419355, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=237, Percent_Identity=27.4261603375527, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=330, Percent_Identity=24.5454545454545, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319876, Length=378, Percent_Identity=23.015873015873, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324410, Length=147, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=209, Percent_Identity=24.4019138755981, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=286, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=366, Percent_Identity=22.4043715846995, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653727, Length=411, Percent_Identity=21.654501216545, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47671; Mature: 47540

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVTAFVADSEEKKVEDAIYRKVTWHILPLLFLCYLCAYLDRVNVGLAKLQMSADLQF
CCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCH
SETVYGLGAGIFFIGFFTVEIPSNILLHKLGARVWIARIMISWGLISGATMFVTTPWAFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
VLRFFLGVAEAGFYPGVILYLTYWYPKERRGRIYALFATAVPFSGIIGGPLSGLIIDGMN
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCC
GVAGWTGWQWMFLLEALPSIVMGIAAFIFLTDHIHKAKWLSDAEKTLLSRNISRDADGKT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VHSVWAALMNRKVWFMTTIYFCLIMGFYGVGFWLPTLINATGVKSAWHVGLLTAIPYASA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
GIAMLLIARSADRRNERRWHLALTCVVGGIGLILSALLSQSIPLAMAGLTLGAMGALSTL
CHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PLFWSIPTAFLNGTAAAAGIAFINSVGNLGGFVSPYMIGFIRDTTESSNLGMYMLAAFLF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LGAGLTLLVPAKLTGKA
HHCCCEEEEECCCCCCC
>Mature Secondary Structure 
SLSVTAFVADSEEKKVEDAIYRKVTWHILPLLFLCYLCAYLDRVNVGLAKLQMSADLQF
CEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCH
SETVYGLGAGIFFIGFFTVEIPSNILLHKLGARVWIARIMISWGLISGATMFVTTPWAFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
VLRFFLGVAEAGFYPGVILYLTYWYPKERRGRIYALFATAVPFSGIIGGPLSGLIIDGMN
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCC
GVAGWTGWQWMFLLEALPSIVMGIAAFIFLTDHIHKAKWLSDAEKTLLSRNISRDADGKT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VHSVWAALMNRKVWFMTTIYFCLIMGFYGVGFWLPTLINATGVKSAWHVGLLTAIPYASA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
GIAMLLIARSADRRNERRWHLALTCVVGGIGLILSALLSQSIPLAMAGLTLGAMGALSTL
CHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
PLFWSIPTAFLNGTAAAAGIAFINSVGNLGGFVSPYMIGFIRDTTESSNLGMYMLAAFLF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LGAGLTLLVPAKLTGKA
HHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]