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The map label for this gene is cobT [H]

Identifier: 182678994

GI number: 182678994

Start: 2319506

End: 2320474

Strand: Reverse

Name: cobT [H]

Synonym: Bind_2029

Alternate gene names: 182678994

Gene position: 2320474-2319506 (Counterclockwise)

Preceding gene: 182678998

Following gene: 182678991

Centisome position: 55.64

GC content: 63.16

Gene sequence:

>969_bases
ATGCCTGCAGCCTCCGAGGCAGCCGTTACTGCTGTGCGCGAACGCCAGGCCCGTCTCACCAAGCCCGAAGGTTCGCTCGG
GCGGCTTGAGGAGATCGTCGCTTTTCTGGCAGCGTGGCAGGACAAGCCACAGCCACAAATGGAACGTCCACTGGTCGCGA
TCTTCGCTGCTAATCATGGCGTGGCGGCCCGTGGTGTATCCGCTTATCCGCCCTCAGTGACCCGGGCGATGATGGAGAAT
TTCGGTAACGGGGGAGCGGCGGTCAATCAGATCTGCGCCAGTTTCGGCACGGGCCTCAAAATTTTCGAACTGGCCCTCGA
TCTGCCGACCGAGGATATTACCCAGAAACCAGCCATGGACGAGGCCGCCGCTGCCGCTACCTTCGCTTTCGGCATGGAGG
CGATTGCTGGCGGCATCGACCTCCTGTGCCTGGGAGAGATGGGGATCGGCAATACGACCGTGGCGGCCGCCGTTTATCAT
GGGCTTTATGGCGGCAAGCCGGAGGATTGGGTGGGGCAGGGGACCGGCGTCGATGCCGAGGGCCTGCGCCGCAAGATCGA
CGCGGTTGGGACGGCGGTCGCGCTGCACAAGGACAATCTCACCGATCCCTTGCAAGTCATGCGTTGCCTTGGCGGACGTG
AAATCGCCGCCATGGCGGGCGCGATCCTGGCTGCCCGCATCGAGCATATTCCCGTGATTCTCGATGGTTATGTGGCCTGC
GCCTCGGCGGCCATTCTCCAGGCCTTGCATCCCGGTGCCATTGATCATTGCCTTGCGGGGCATGTTTCCGCCGAGAAGCC
TCACGCCAATGTGCTCGCGCGGCTCGGCAAGGCGCCGCTTCTCGATCTTGGTCTGCGCCTCGGTGAAGGCTCCGGCGCTG
CGCTCGCCATCGGCATTGTCAAGGCGGCCTTGGCTTGCCATGATGGCATGGCGACCTTCGATGAAGCCAAGGTCCCGGGC
CAAGTTTAA

Upstream 100 bases:

>100_bases
TGATTTCCAGCATCGGCTACCGTTCCCGACACTCTGATCCGATCGATTCCCGCCCTTGTCCATCTCTCCCTTCGACGATA
TCCGTGCCCTTCTGCCTCTC

Downstream 100 bases:

>100_bases
GTTTTGCCAGTTTAATCCTTCAGAGTCTGTGGACTGTCATCGCGAAGCGCCTTGGCGAGTAGGCGCCAATCCGCCCATGC
GCGTTTTTTCTCCGCCGGCT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPAASEAAVTAVRERQARLTKPEGSLGRLEEIVAFLAAWQDKPQPQMERPLVAIFAANHGVAARGVSAYPPSVTRAMMEN
FGNGGAAVNQICASFGTGLKIFELALDLPTEDITQKPAMDEAAAAATFAFGMEAIAGGIDLLCLGEMGIGNTTVAAAVYH
GLYGGKPEDWVGQGTGVDAEGLRRKIDAVGTAVALHKDNLTDPLQVMRCLGGREIAAMAGAILAARIEHIPVILDGYVAC
ASAAILQALHPGAIDHCLAGHVSAEKPHANVLARLGKAPLLDLGLRLGEGSGAALAIGIVKAALACHDGMATFDEAKVPG
QV

Sequences:

>Translated_322_residues
MPAASEAAVTAVRERQARLTKPEGSLGRLEEIVAFLAAWQDKPQPQMERPLVAIFAANHGVAARGVSAYPPSVTRAMMEN
FGNGGAAVNQICASFGTGLKIFELALDLPTEDITQKPAMDEAAAAATFAFGMEAIAGGIDLLCLGEMGIGNTTVAAAVYH
GLYGGKPEDWVGQGTGVDAEGLRRKIDAVGTAVALHKDNLTDPLQVMRCLGGREIAAMAGAILAARIEHIPVILDGYVAC
ASAAILQALHPGAIDHCLAGHVSAEKPHANVLARLGKAPLLDLGLRLGEGSGAALAIGIVKAALACHDGMATFDEAKVPG
QV
>Mature_321_residues
PAASEAAVTAVRERQARLTKPEGSLGRLEEIVAFLAAWQDKPQPQMERPLVAIFAANHGVAARGVSAYPPSVTRAMMENF
GNGGAAVNQICASFGTGLKIFELALDLPTEDITQKPAMDEAAAAATFAFGMEAIAGGIDLLCLGEMGIGNTTVAAAVYHG
LYGGKPEDWVGQGTGVDAEGLRRKIDAVGTAVALHKDNLTDPLQVMRCLGGREIAAMAGAILAARIEHIPVILDGYVACA
SAAILQALHPGAIDHCLAGHVSAEKPHANVLARLGKAPLLDLGLRLGEGSGAALAIGIVKAALACHDGMATFDEAKVPGQ
V

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=342, Percent_Identity=31.2865497076023, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 33093; Mature: 32961

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAASEAAVTAVRERQARLTKPEGSLGRLEEIVAFLAAWQDKPQPQMERPLVAIFAANHG
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCC
VAARGVSAYPPSVTRAMMENFGNGGAAVNQICASFGTGLKIFELALDLPTEDITQKPAMD
CHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHCCCCHH
EAAAAATFAFGMEAIAGGIDLLCLGEMGIGNTTVAAAVYHGLYGGKPEDWVGQGTGVDAE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
GLRRKIDAVGTAVALHKDNLTDPLQVMRCLGGREIAAMAGAILAARIEHIPVILDGYVAC
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
ASAAILQALHPGAIDHCLAGHVSAEKPHANVLARLGKAPLLDLGLRLGEGSGAALAIGIV
HHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHCEECCCCCCCHHHHHH
KAALACHDGMATFDEAKVPGQV
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PAASEAAVTAVRERQARLTKPEGSLGRLEEIVAFLAAWQDKPQPQMERPLVAIFAANHG
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCC
VAARGVSAYPPSVTRAMMENFGNGGAAVNQICASFGTGLKIFELALDLPTEDITQKPAMD
CHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHCCCCHH
EAAAAATFAFGMEAIAGGIDLLCLGEMGIGNTTVAAAVYHGLYGGKPEDWVGQGTGVDAE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
GLRRKIDAVGTAVALHKDNLTDPLQVMRCLGGREIAAMAGAILAARIEHIPVILDGYVAC
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
ASAAILQALHPGAIDHCLAGHVSAEKPHANVLARLGKAPLLDLGLRLGEGSGAALAIGIV
HHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHCEECCCCCCCHHHHHH
KAALACHDGMATFDEAKVPGQV
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA