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The map label for this gene is ywlC [H]

Identifier: 182678988

GI number: 182678988

Start: 2312260

End: 2313240

Strand: Direct

Name: ywlC [H]

Synonym: Bind_2023

Alternate gene names: 182678988

Gene position: 2312260-2313240 (Clockwise)

Preceding gene: 182678986

Following gene: 182678992

Centisome position: 55.45

GC content: 64.32

Gene sequence:

>981_bases
TTGTCTGTTCCCCCTGTTTCACAGGATGATCTCACGTCTGAAATCACGAAGGCGGCTTCGATCCTTCGCCAAGGCGGCCT
CGTCGCTTTCCCGACCGAGACGGTTTATGGGCTCGGCGCCGACGCGACGCGCGATGAAGCTGTCGCCAAAATCTATGCGG
CCAAGGAACGGCCCTCCTTCAACCCGCTGATCGCCCATGTTGCGAGCCTCGCAGAAGCCCAGTGTCACGGGATTTTCTCC
GATATGGCCTTGCGGCTCGCCGCCTGCTTTTGGCCTGGCCCTCTCACGCTCGTGGTGCCCGTTTCACCGGAAAGCAAGAT
TTGCGCCCTGGCGCGGGCTGGACTCGACAGCGTGGCCCTGCGCGTCCCGGCGCATCCGATCGCGCGTGCCTTGATCGAAG
CGACGGGTCTGCCGCTCGCGGCGCCTTCCGCCAATCGCTCTGGCCGGGTGAGCCCGGTCAGCGCCGAGCATGTCCGCGAG
GACCTTGGCGATCGTGTCGACCTGATCCTCGATGGCGGTCGCTGCCCTGTCGGCGTGGAATCGACCATTATCGACTGTCT
CGAAGCACAACCTCGCCTCTTGCGGCCGGGCGGCATTCCCCGCGAGGCCATCGAAACCTGTCTCGGCCGCATCCTTGAGG
CACCACCGCGTCTTACTGCCACTTCTCCCTTGCGCGGGCCTGGACTCCTGGCCTCTCATTATGCGCCGCGCGCCAAGGTC
CGGCTCGACGCCACAGACTTACAAAAAGGAGAAGCAGGACTGGATTTCGGCGGTCACTTCGCGAAGGCGGCCCACACTCT
CGATCTGTCGCCGAGCGGCGATCTCACCGAGGCTGCGGCACATCTCTTCACCTATCTCCGCCATCTCGACGCTTTGGGAT
TAGAGACGATCGCGGTGGCGCCCATCCCCGAAACCGGTCTCGGCGAGGCGATCAACGACCGGCTGCGCCGCGCCGCCGCG
CCAAGACATCCAGCATCATAA

Upstream 100 bases:

>100_bases
GCAAAACGCCCGCACATGGCTGCTTCTCCCCCATCTCATCCATCCCTATCCATCAGCCTTATCTTTGGCGCGGTCGGCAG
CAAATCGAAAGGCCAATCCT

Downstream 100 bases:

>100_bases
GCCTATTGGGCCGCTGGAGCCGGCGCCACCGAAGCGGTCATCTCGGGCGTAGCCAGAGTTGGTGCATCCTTGTCGGGAAA
CACCATTTCCCAGCCACCCC

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSVPPVSQDDLTSEITKAASILRQGGLVAFPTETVYGLGADATRDEAVAKIYAAKERPSFNPLIAHVASLAEAQCHGIFS
DMALRLAACFWPGPLTLVVPVSPESKICALARAGLDSVALRVPAHPIARALIEATGLPLAAPSANRSGRVSPVSAEHVRE
DLGDRVDLILDGGRCPVGVESTIIDCLEAQPRLLRPGGIPREAIETCLGRILEAPPRLTATSPLRGPGLLASHYAPRAKV
RLDATDLQKGEAGLDFGGHFAKAAHTLDLSPSGDLTEAAAHLFTYLRHLDALGLETIAVAPIPETGLGEAINDRLRRAAA
PRHPAS

Sequences:

>Translated_326_residues
MSVPPVSQDDLTSEITKAASILRQGGLVAFPTETVYGLGADATRDEAVAKIYAAKERPSFNPLIAHVASLAEAQCHGIFS
DMALRLAACFWPGPLTLVVPVSPESKICALARAGLDSVALRVPAHPIARALIEATGLPLAAPSANRSGRVSPVSAEHVRE
DLGDRVDLILDGGRCPVGVESTIIDCLEAQPRLLRPGGIPREAIETCLGRILEAPPRLTATSPLRGPGLLASHYAPRAKV
RLDATDLQKGEAGLDFGGHFAKAAHTLDLSPSGDLTEAAAHLFTYLRHLDALGLETIAVAPIPETGLGEAINDRLRRAAA
PRHPAS
>Mature_325_residues
SVPPVSQDDLTSEITKAASILRQGGLVAFPTETVYGLGADATRDEAVAKIYAAKERPSFNPLIAHVASLAEAQCHGIFSD
MALRLAACFWPGPLTLVVPVSPESKICALARAGLDSVALRVPAHPIARALIEATGLPLAAPSANRSGRVSPVSAEHVRED
LGDRVDLILDGGRCPVGVESTIIDCLEAQPRLLRPGGIPREAIETCLGRILEAPPRLTATSPLRGPGLLASHYAPRAKVR
LDATDLQKGEAGLDFGGHFAKAAHTLDLSPSGDLTEAAAHLFTYLRHLDALGLETIAVAPIPETGLGEAINDRLRRAAAP
RHPAS

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI87081864, Length=185, Percent_Identity=28.6486486486486, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367210, Length=152, Percent_Identity=32.2368421052632, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=208, Percent_Identity=35.0961538461538, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193205175, Length=127, Percent_Identity=39.3700787401575, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=385, Percent_Identity=35.8441558441558, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34185; Mature: 34053

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPPVSQDDLTSEITKAASILRQGGLVAFPTETVYGLGADATRDEAVAKIYAAKERPSF
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHEECCCCCCHHHHHHHHHHHCCCCCC
NPLIAHVASLAEAQCHGIFSDMALRLAACFWPGPLTLVVPVSPESKICALARAGLDSVAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCHHHEEE
RVPAHPIARALIEATGLPLAAPSANRSGRVSPVSAEHVREDLGDRVDLILDGGRCPVGVE
ECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHH
STIIDCLEAQPRLLRPGGIPREAIETCLGRILEAPPRLTATSPLRGPGLLASHYAPRAKV
HHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCEE
RLDATDLQKGEAGLDFGGHFAKAAHTLDLSPSGDLTEAAAHLFTYLRHLDALGLETIAVA
EECHHHCCCCCCCCCCCCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEC
PIPETGLGEAINDRLRRAAAPRHPAS
CCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVPPVSQDDLTSEITKAASILRQGGLVAFPTETVYGLGADATRDEAVAKIYAAKERPSF
CCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHEECCCCCCHHHHHHHHHHHCCCCCC
NPLIAHVASLAEAQCHGIFSDMALRLAACFWPGPLTLVVPVSPESKICALARAGLDSVAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCHHHEEE
RVPAHPIARALIEATGLPLAAPSANRSGRVSPVSAEHVREDLGDRVDLILDGGRCPVGVE
ECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCHH
STIIDCLEAQPRLLRPGGIPREAIETCLGRILEAPPRLTATSPLRGPGLLASHYAPRAKV
HHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCEE
RLDATDLQKGEAGLDFGGHFAKAAHTLDLSPSGDLTEAAAHLFTYLRHLDALGLETIAVA
EECHHHCCCCCCCCCCCCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEC
PIPETGLGEAINDRLRRAAAPRHPAS
CCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]