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The map label for this gene is glcD [H]

Identifier: 182678981

GI number: 182678981

Start: 2302468

End: 2303892

Strand: Direct

Name: glcD [H]

Synonym: Bind_2016

Alternate gene names: 182678981

Gene position: 2302468-2303892 (Clockwise)

Preceding gene: 182678980

Following gene: 182678983

Centisome position: 55.21

GC content: 57.4

Gene sequence:

>1425_bases
ATGGACACACAATCTTTCTCCGGCGAAGATCTCCTGTCACGTCTGCGCCTTGTGCTTGGCGAAAAACATGTTTTGACGGA
GGGCGTGGATATGGCCGCCTTCCTTGAGGAACCGCGGGGCCTTTATCATGGCCACGCGCTCGCCGTTGTCCGGCCGGGAT
CGACGCAAGAGGTCGCGAGCGTGATGACCTTGTGCGCCGAGGCACAGACCAATGTGGTCACGCAAGGAGGCAATACCGGT
CTTGTGGGTGGCCAAATCCCCCTCGCCGGCACCAAGCCGATCGTGCTCTCCCTCACCCGTCTGAATCAGTTACGTGAAAT
CGATCTGCCATCGGAAACGATGACTGTCGAGGCGGGAATGACACTCGCGGCCGTTCAAGCCGCTGCGGATACGGTCGAAA
GATTATTCCCTCTCTCGCTCGCCTCTGAAGGGTCCTGCACAATCGGTGGCAATCTCGCGACCAATGCCGGGGGTACCAAT
GTCATCGCTTATGGCAATGCGCGAGCACTGGTGCTGGGTCTCGAAGTCGTTCTCGCCGATGGCCGGATTCTTCACGATCT
CTCCAAGCTCAAGAAGGATAATACGGGTTATGATTTGAAAGACCTGTTCATCGGCTCGGAAGGAACGCTTGGCATCATCA
CGGCCGCTGTCCTGAAATTGTTCCCGAAACCCCGCTCACGCGAAACGGCTTTCATTGGCCTTTCCAGCCCACGCGCGGCT
GTCGATTTTCTGACGCTGGCTCGCGCCGAGGCGGGCCCGAATATCGTGGCCTTCGAATTGATCCCTCGCATCGGAATCGA
TTTCGTCCTCGCGCATAGCGAGGGCAATCGTGATCCCTTCAACAAGCAACACGCCTGGTATGTTCTTCTCGAATTGGCCA
GCCCACAAAAGCAAGGGCTCGATACCATTCTACTGCATGTGCTTGAAGCCGGGATGGAAAAAGGCTTGATCGAGGATGCC
GCCATTGCCGCCTCGCTGGCTCAGCACGAAGCCTTCTGGCGGTTGCGTGAACTTCTGTCCGAAGTGCAGGGCCGCGAAGG
CGGCTCGATCAAACATGATGTGTCCGTACCCATCGCCGCCGTGCCGGATTTCCTGGATGATGTCGCAAACACTCTCGCCA
AAGCCCTGCCCGGCTCGCGTCCCGTGCCCTTCGGGCATCTCGGTGATGGCAATATTCATTGCAATATTTCACAACCGATC
GGTGCCGACAAACAGGCTTTTCTTGACCGCTGGGACGAGGTGAACACGCTGGTTCATGGGCTCGTCGCCAAATATCACGG
CTCGATTTCGGCCGAGCACGGCATCGGGCAATTGAAACGCAAGCTGCTACCGCAGGTGAAGGATCCCGTGGCCCTTGATG
TGATGCGCGCCGTGAAAACAGCGCTTGATCCCCAAAACCTCCTCAATCCCGGTAAAGTTTTATAG

Upstream 100 bases:

>100_bases
TGCCGTTCTCCATTTATCCATTCCGCGATTGATCATTAATTGGGCAGATATCAAACGCGTCTTCCACCCATGATGCTTGC
CCGAACAGGCTGATTTTGCC

Downstream 100 bases:

>100_bases
GGGCTTCGTCGCAAACACATTCGGATCTCAAGATCAAATATTTGATATCAAAATATATCAATATCCGAATTGATATCCAC
ATCTGAGCTTTTCGCGGACG

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDTQSFSGEDLLSRLRLVLGEKHVLTEGVDMAAFLEEPRGLYHGHALAVVRPGSTQEVASVMTLCAEAQTNVVTQGGNTG
LVGGQIPLAGTKPIVLSLTRLNQLREIDLPSETMTVEAGMTLAAVQAAADTVERLFPLSLASEGSCTIGGNLATNAGGTN
VIAYGNARALVLGLEVVLADGRILHDLSKLKKDNTGYDLKDLFIGSEGTLGIITAAVLKLFPKPRSRETAFIGLSSPRAA
VDFLTLARAEAGPNIVAFELIPRIGIDFVLAHSEGNRDPFNKQHAWYVLLELASPQKQGLDTILLHVLEAGMEKGLIEDA
AIAASLAQHEAFWRLRELLSEVQGREGGSIKHDVSVPIAAVPDFLDDVANTLAKALPGSRPVPFGHLGDGNIHCNISQPI
GADKQAFLDRWDEVNTLVHGLVAKYHGSISAEHGIGQLKRKLLPQVKDPVALDVMRAVKTALDPQNLLNPGKVL

Sequences:

>Translated_474_residues
MDTQSFSGEDLLSRLRLVLGEKHVLTEGVDMAAFLEEPRGLYHGHALAVVRPGSTQEVASVMTLCAEAQTNVVTQGGNTG
LVGGQIPLAGTKPIVLSLTRLNQLREIDLPSETMTVEAGMTLAAVQAAADTVERLFPLSLASEGSCTIGGNLATNAGGTN
VIAYGNARALVLGLEVVLADGRILHDLSKLKKDNTGYDLKDLFIGSEGTLGIITAAVLKLFPKPRSRETAFIGLSSPRAA
VDFLTLARAEAGPNIVAFELIPRIGIDFVLAHSEGNRDPFNKQHAWYVLLELASPQKQGLDTILLHVLEAGMEKGLIEDA
AIAASLAQHEAFWRLRELLSEVQGREGGSIKHDVSVPIAAVPDFLDDVANTLAKALPGSRPVPFGHLGDGNIHCNISQPI
GADKQAFLDRWDEVNTLVHGLVAKYHGSISAEHGIGQLKRKLLPQVKDPVALDVMRAVKTALDPQNLLNPGKVL
>Mature_474_residues
MDTQSFSGEDLLSRLRLVLGEKHVLTEGVDMAAFLEEPRGLYHGHALAVVRPGSTQEVASVMTLCAEAQTNVVTQGGNTG
LVGGQIPLAGTKPIVLSLTRLNQLREIDLPSETMTVEAGMTLAAVQAAADTVERLFPLSLASEGSCTIGGNLATNAGGTN
VIAYGNARALVLGLEVVLADGRILHDLSKLKKDNTGYDLKDLFIGSEGTLGIITAAVLKLFPKPRSRETAFIGLSSPRAA
VDFLTLARAEAGPNIVAFELIPRIGIDFVLAHSEGNRDPFNKQHAWYVLLELASPQKQGLDTILLHVLEAGMEKGLIEDA
AIAASLAQHEAFWRLRELLSEVQGREGGSIKHDVSVPIAAVPDFLDDVANTLAKALPGSRPVPFGHLGDGNIHCNISQPI
GADKQAFLDRWDEVNTLVHGLVAKYHGSISAEHGIGQLKRKLLPQVKDPVALDVMRAVKTALDPQNLLNPGKVL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=436, Percent_Identity=37.1559633027523, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI37595756, Length=489, Percent_Identity=32.719836400818, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI37595754, Length=514, Percent_Identity=30.9338521400778, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4501993, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789351, Length=447, Percent_Identity=30.6487695749441, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787977, Length=501, Percent_Identity=24.9500998003992, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994907, Length=225, Percent_Identity=27.1111111111111, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994914, Length=159, Percent_Identity=28.3018867924528, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534361, Length=455, Percent_Identity=33.6263736263736, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71992373, Length=486, Percent_Identity=28.6008230452675, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992381, Length=486, Percent_Identity=27.5720164609054, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71992392, Length=388, Percent_Identity=29.8969072164948, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=242, Percent_Identity=23.1404958677686, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320023, Length=477, Percent_Identity=34.5911949685535, Blast_Score=289, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6320764, Length=472, Percent_Identity=33.0508474576271, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6320027, Length=439, Percent_Identity=24.1457858769932, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI18921117, Length=462, Percent_Identity=37.2294372294372, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24639277, Length=462, Percent_Identity=37.2294372294372, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24639275, Length=462, Percent_Identity=37.2294372294372, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50480; Mature: 50480

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQSFSGEDLLSRLRLVLGEKHVLTEGVDMAAFLEEPRGLYHGHALAVVRPGSTQEVAS
CCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCHHHHHH
VMTLCAEAQTNVVTQGGNTGLVGGQIPLAGTKPIVLSLTRLNQLREIDLPSETMTVEAGM
HHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHCCCCCCCEEEECCC
TLAAVQAAADTVERLFPLSLASEGSCTIGGNLATNAGGTNVIAYGNARALVLGLEVVLAD
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEECCCCCCEEEEECCCEEEEEEEEHHEEC
GRILHDLSKLKKDNTGYDLKDLFIGSEGTLGIITAAVLKLFPKPRSRETAFIGLSSPRAA
CHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
VDFLTLARAEAGPNIVAFELIPRIGIDFVLAHSEGNRDPFNKQHAWYVLLELASPQKQGL
HHHHHHHHHCCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHH
DTILLHVLEAGMEKGLIEDAAIAASLAQHEAFWRLRELLSEVQGREGGSIKHDVSVPIAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VPDFLDDVANTLAKALPGSRPVPFGHLGDGNIHCNISQPIGADKQAFLDRWDEVNTLVHG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LVAKYHGSISAEHGIGQLKRKLLPQVKDPVALDVMRAVKTALDPQNLLNPGKVL
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCC
>Mature Secondary Structure
MDTQSFSGEDLLSRLRLVLGEKHVLTEGVDMAAFLEEPRGLYHGHALAVVRPGSTQEVAS
CCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCHHHHHH
VMTLCAEAQTNVVTQGGNTGLVGGQIPLAGTKPIVLSLTRLNQLREIDLPSETMTVEAGM
HHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHCCCCCCCEEEECCC
TLAAVQAAADTVERLFPLSLASEGSCTIGGNLATNAGGTNVIAYGNARALVLGLEVVLAD
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEECCCCCCEEEEECCCEEEEEEEEHHEEC
GRILHDLSKLKKDNTGYDLKDLFIGSEGTLGIITAAVLKLFPKPRSRETAFIGLSSPRAA
CHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
VDFLTLARAEAGPNIVAFELIPRIGIDFVLAHSEGNRDPFNKQHAWYVLLELASPQKQGL
HHHHHHHHHCCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHH
DTILLHVLEAGMEKGLIEDAAIAASLAQHEAFWRLRELLSEVQGREGGSIKHDVSVPIAA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VPDFLDDVANTLAKALPGSRPVPFGHLGDGNIHCNISQPIGADKQAFLDRWDEVNTLVHG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LVAKYHGSISAEHGIGQLKRKLLPQVKDPVALDVMRAVKTALDPQNLLNPGKVL
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]