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The map label for this gene is tadA [H]

Identifier: 182678875

GI number: 182678875

Start: 2176461

End: 2176916

Strand: Reverse

Name: tadA [H]

Synonym: Bind_1908

Alternate gene names: 182678875

Gene position: 2176916-2176461 (Counterclockwise)

Preceding gene: 182678876

Following gene: 182678871

Centisome position: 52.2

GC content: 61.84

Gene sequence:

>456_bases
GTGAAGCCGACGCCGCGTCCCGATCCGTTCTCCTTGGCTTTCGAGGAGGCCCACAAGGCGGCGGCGCGTGGGGAGGTACC
GGTCGGCGCGGTGATCATGCGTGAGGGGATCATATTGGCGCGGGCGGGCAATCAGGTTCTTGCCGATAAGGATCCGACCG
CCCATGCGGAAATGCTGGCTATTCGCCAGGCTTGCGCCGTGCTCGGTTCCGAACGGCTCATTGGTTGCGATCTCTACGTG
ACGCTTGAGCCTTGTGCCATGTGTGCGGCAGCCATTGCCCATGCCCGCTTGCGCAGGCTCTATTTTTCGGCATCCGATCC
GAAAGGGGGAGGGGTCGAACATGGTGCGCGGATTTTCGCGCAGCCGACCTGCCATCACGTGACGGAAATATATGGCGGCT
TGCGGGAAAGCGAGGCCGCAGCCCTTTTACGGGCTTTTTTCCTGGAACGGCGATAA

Upstream 100 bases:

>100_bases
AAGAGGCAGGAAAAGGATGAAGCCACAACCGCTTTGAAGCTCGGAAAGGGTGATTTTGAAGAAACCGAAGAACACGCCGG
ACTCACCGGTCTTTGACGAG

Downstream 100 bases:

>100_bases
ATATCCGATTGGGCCGAAAAAGGGCGTTCCCTTTAGACGAGGGGACGGGCGTGGGTTTTCCTGACGGGCCCCTCTTTATA
AAAATGATGGGTTTCGCGTT

Product: CMP/dCMP deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKPTPRPDPFSLAFEEAHKAAARGEVPVGAVIMREGIILARAGNQVLADKDPTAHAEMLAIRQACAVLGSERLIGCDLYV
TLEPCAMCAAAIAHARLRRLYFSASDPKGGGVEHGARIFAQPTCHHVTEIYGGLRESEAAALLRAFFLERR

Sequences:

>Translated_151_residues
MKPTPRPDPFSLAFEEAHKAAARGEVPVGAVIMREGIILARAGNQVLADKDPTAHAEMLAIRQACAVLGSERLIGCDLYV
TLEPCAMCAAAIAHARLRRLYFSASDPKGGGVEHGARIFAQPTCHHVTEIYGGLRESEAAALLRAFFLERR
>Mature_151_residues
MKPTPRPDPFSLAFEEAHKAAARGEVPVGAVIMREGIILARAGNQVLADKDPTAHAEMLAIRQACAVLGSERLIGCDLYV
TLEPCAMCAAAIAHARLRRLYFSASDPKGGGVEHGARIFAQPTCHHVTEIYGGLRESEAAALLRAFFLERR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=139, Percent_Identity=42.4460431654676, Blast_Score=108, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17554608, Length=109, Percent_Identity=39.4495412844037, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=142, Percent_Identity=33.8028169014084, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=80, Percent_Identity=43.75, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355527, Length=141, Percent_Identity=34.0425531914894, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 16278; Mature: 16278

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTPRPDPFSLAFEEAHKAAARGEVPVGAVIMREGIILARAGNQVLADKDPTAHAEMLA
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCEEECCCCCCHHHHHHH
IRQACAVLGSERLIGCDLYVTLEPCAMCAAAIAHARLRRLYFSASDPKGGGVEHGARIFA
HHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
QPTCHHVTEIYGGLRESEAAALLRAFFLERR
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPTPRPDPFSLAFEEAHKAAARGEVPVGAVIMREGIILARAGNQVLADKDPTAHAEMLA
CCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCEEECCCCCCHHHHHHH
IRQACAVLGSERLIGCDLYVTLEPCAMCAAAIAHARLRRLYFSASDPKGGGVEHGARIFA
HHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
QPTCHHVTEIYGGLRESEAAALLRAFFLERR
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]