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The map label for this gene is pleC [H]

Identifier: 182678851

GI number: 182678851

Start: 2148575

End: 2149744

Strand: Direct

Name: pleC [H]

Synonym: Bind_1884

Alternate gene names: 182678851

Gene position: 2148575-2149744 (Clockwise)

Preceding gene: 182678850

Following gene: 182678854

Centisome position: 51.52

GC content: 56.24

Gene sequence:

>1170_bases
ATGAGCAAAGATCGATCCCAAGGGATCCTCGTCGTTGATGATGATCCAGATTTCGGAGAATCCCTTTTCGATATTCTTGA
TTATCGCGGCTATCGGGTCATCAATGTTCACGATGCGGAATCCGCTTTGGAAGCGCTACGGAACGAAAGACCCGCCGTCG
CCATGGTCGATATTCGCCTTGGCGGAACATCCGGCGTCGATCTGCTGTCGCGTTTGAAGGCTGAAGCGCCCGGCCTGATC
GGCATTATGATCACCGCCCATGTCGATACGCCCTCGGCGATCGAAGCCATGCGGCGGGGGGCTTATGACTATATCGACAA
ATCCTGCGCACCCGGCGAACTCGTCGCCATTCTCGAGCGTGCCTTCGAGACGCATCATTTGCGCATGGAAAAGTCCCGTA
TGATCGAAGCCCTTCGTCTCGCCAAAGAAGGAGCCGAGGCCGCCAATCAGGCGAAATCCAATTTTCTCGCCACGATCAGC
CATGAATTGCGTACGCCACTCAATGCCATTATCGGCTTCTCAAATCTTATCCTCATGGAACTGATGGGACCGCTCTCCAA
CGAGCGCTATCGCGAATATTTACGTGATATCAATGCGAGCGGCGAACATCTCCTGTCGATCATCAACGACATTCTCGATC
TCACCAAGGCCGAGGCCGGCCAAACGGAATTGTTCGAATCCGTGATCCATCCCCGCGATGCCATCATACCGGTCGAGCGC
CTCTTGATGCCCAAGGCACGGGAAGCGGGCCTGACCCTGACCTCGAACATTACCGAACATCTGCCTCTGCTGCGCGCCGA
CGAACGCAAAGCCAAGCAGATCTTCCTTAATCTCCTGTCCAATGCGGTTAAATTCACACCACCCGGCGGTTCCATTGAAA
TCGACGCCCATCTCACTCACAAGGGCGATCTGGCGATTGCCGTGGCCGATACGGGCATCGGCATCGCGCCGGAACATATT
GATCGTGTTTGCGAGCCTTTCGTGCAGATCGACAGTTCACTCAGCCGCCGTCACGATGGCACGGGGCTTGGCCTGCCGCT
CGTCAAATCCTTCATGGAATTGCATGAGGGCAGCCTGCATCTCAGGAGCAAAAGCGGGATCGGCACTTGCGCCATCGTCA
CCTTTCCCGCGAAACGGCTGGTCCTTCCGCAGTCCCGCCTCTCGGCATGA

Upstream 100 bases:

>100_bases
TTCTCATCAAGCCCTTCGATCCCCAAACTCTGCTCCACACCCTTGATCATCTCCTGCATCCGCAAGAGGCAACACCAAAC
GCAGGTTCGAGGGCACTTGC

Downstream 100 bases:

>100_bases
TCAGCGGACAACCAAGCGCCGTTCGATTTCAATCATTGGTCCGGAAGGCTTCGCCGCTTTCAAGCCCGCGCGTCGCCCCT
TTCATCGATTCAAAAGGATT

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSKDRSQGILVVDDDPDFGESLFDILDYRGYRVINVHDAESALEALRNERPAVAMVDIRLGGTSGVDLLSRLKAEAPGLI
GIMITAHVDTPSAIEAMRRGAYDYIDKSCAPGELVAILERAFETHHLRMEKSRMIEALRLAKEGAEAANQAKSNFLATIS
HELRTPLNAIIGFSNLILMELMGPLSNERYREYLRDINASGEHLLSIINDILDLTKAEAGQTELFESVIHPRDAIIPVER
LLMPKAREAGLTLTSNITEHLPLLRADERKAKQIFLNLLSNAVKFTPPGGSIEIDAHLTHKGDLAIAVADTGIGIAPEHI
DRVCEPFVQIDSSLSRRHDGTGLGLPLVKSFMELHEGSLHLRSKSGIGTCAIVTFPAKRLVLPQSRLSA

Sequences:

>Translated_389_residues
MSKDRSQGILVVDDDPDFGESLFDILDYRGYRVINVHDAESALEALRNERPAVAMVDIRLGGTSGVDLLSRLKAEAPGLI
GIMITAHVDTPSAIEAMRRGAYDYIDKSCAPGELVAILERAFETHHLRMEKSRMIEALRLAKEGAEAANQAKSNFLATIS
HELRTPLNAIIGFSNLILMELMGPLSNERYREYLRDINASGEHLLSIINDILDLTKAEAGQTELFESVIHPRDAIIPVER
LLMPKAREAGLTLTSNITEHLPLLRADERKAKQIFLNLLSNAVKFTPPGGSIEIDAHLTHKGDLAIAVADTGIGIAPEHI
DRVCEPFVQIDSSLSRRHDGTGLGLPLVKSFMELHEGSLHLRSKSGIGTCAIVTFPAKRLVLPQSRLSA
>Mature_388_residues
SKDRSQGILVVDDDPDFGESLFDILDYRGYRVINVHDAESALEALRNERPAVAMVDIRLGGTSGVDLLSRLKAEAPGLIG
IMITAHVDTPSAIEAMRRGAYDYIDKSCAPGELVAILERAFETHHLRMEKSRMIEALRLAKEGAEAANQAKSNFLATISH
ELRTPLNAIIGFSNLILMELMGPLSNERYREYLRDINASGEHLLSIINDILDLTKAEAGQTELFESVIHPRDAIIPVERL
LMPKAREAGLTLTSNITEHLPLLRADERKAKQIFLNLLSNAVKFTPPGGSIEIDAHLTHKGDLAIAVADTGIGIAPEHID
RVCEPFVQIDSSLSRRHDGTGLGLPLVKSFMELHEGSLHLRSKSGIGTCAIVTFPAKRLVLPQSRLSA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=39.662447257384, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=35.2713178294574, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=35.0597609561753, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=34.3511450381679, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI48994928, Length=281, Percent_Identity=32.0284697508897, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=32.1739130434783, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786783, Length=253, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=301, Percent_Identity=25.2491694352159, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=25.2032520325203, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=26.6094420600858, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=26.3598326359833, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790299, Length=128, Percent_Identity=34.375, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=25.8771929824561, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.0508474576271, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=26.5060240963855, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42622; Mature: 42490

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDRSQGILVVDDDPDFGESLFDILDYRGYRVINVHDAESALEALRNERPAVAMVDIRL
CCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEEE
GGTSGVDLLSRLKAEAPGLIGIMITAHVDTPSAIEAMRRGAYDYIDKSCAPGELVAILER
CCCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHH
AFETHHLRMEKSRMIEALRLAKEGAEAANQAKSNFLATISHELRTPLNAIIGFSNLILME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMGPLSNERYREYLRDINASGEHLLSIINDILDLTKAEAGQTELFESVIHPRDAIIPVER
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHH
LLMPKAREAGLTLTSNITEHLPLLRADERKAKQIFLNLLSNAVKFTPPGGSIEIDAHLTH
HHCCCHHHCCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEC
KGDLAIAVADTGIGIAPEHIDRVCEPFVQIDSSLSRRHDGTGLGLPLVKSFMELHEGSLH
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEE
LRSKSGIGTCAIVTFPAKRLVLPQSRLSA
EECCCCCCEEEEEEECHHHHCCCHHHHCC
>Mature Secondary Structure 
SKDRSQGILVVDDDPDFGESLFDILDYRGYRVINVHDAESALEALRNERPAVAMVDIRL
CCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEEE
GGTSGVDLLSRLKAEAPGLIGIMITAHVDTPSAIEAMRRGAYDYIDKSCAPGELVAILER
CCCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHH
AFETHHLRMEKSRMIEALRLAKEGAEAANQAKSNFLATISHELRTPLNAIIGFSNLILME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMGPLSNERYREYLRDINASGEHLLSIINDILDLTKAEAGQTELFESVIHPRDAIIPVER
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHH
LLMPKAREAGLTLTSNITEHLPLLRADERKAKQIFLNLLSNAVKFTPPGGSIEIDAHLTH
HHCCCHHHCCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEC
KGDLAIAVADTGIGIAPEHIDRVCEPFVQIDSSLSRRHDGTGLGLPLVKSFMELHEGSLH
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEE
LRSKSGIGTCAIVTFPAKRLVLPQSRLSA
EECCCCCCEEEEEEECHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]