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The map label for this gene is zraR [H]

Identifier: 182678850

GI number: 182678850

Start: 2147826

End: 2148578

Strand: Direct

Name: zraR [H]

Synonym: Bind_1883

Alternate gene names: 182678850

Gene position: 2147826-2148578 (Clockwise)

Preceding gene: 182678849

Following gene: 182678851

Centisome position: 51.5

GC content: 55.91

Gene sequence:

>753_bases
ATGAGAAAACATATTTTCATCGTTGACGACGATCTCGATCATGCCGAGAGCCTTGCCGAAATTCTCGAATTGCAGGGCCA
TGACGTCGAACTCGCGCAATCAGGCGAATCCGCTATCGCCCGTTTCGCCGAGAAAGATTTCGACCTCGTCTTCATGGATG
TGAAACTGCCCGTCATGAATGGCGTCGAGACTTTCTTCGCCTTTCGCCGCCTGCGGCCGCAAGCCCATGTCTTCATGATG
ACCGGCTATAGTGTCGAACAGCTCGTCGCCGAAGCAATCGACAATGGCGCGCTCGGCGTCCTCTATAAACCCTTCAGCGC
GAATGATCTTCTCGATGCCGTGGCGCAAGTGGAGCCGCGCGGCCGTATTCTCGTTGCCGATGACAATGCCATCCTGATCG
ACCAGGTCGCGCCCATCCTGTCGGCGGCTGGCTATGCCGTCGAAATCGCGCATAACAGCCTCGACCAGCTCGATTGCGAC
CAACTCTCCGAGATCGATTGCATGATCGTCGATATGGACCGATCGCTCCTGCGTGGAATGGAACTCTGTGTCGATTTCAA
GGACCGGCTCCCGAGCCTGCCGAAACTGCTCATCCTCGGGTCGGAAAACGACGAAAAAGCCGCGCAGTTTTCCTTGCTCA
CACAAGGCATTCTCATCAAGCCCTTCGATCCCCAAACTCTGCTCCACACCCTTGATCATCTCCTGCATCCGCAAGAGGCA
ACACCAAACGCAGGTTCGAGGGCACTTGCATGA

Upstream 100 bases:

>100_bases
TCGTCGAGCAACATGGCGGCACAATCACTTTGGCCAGCACTCTTGGCCAAGGGACTGAAGTAACCGTTGTTATCCCACAT
GAAAGACAGGAATTGGCCGC

Downstream 100 bases:

>100_bases
GCAAAGATCGATCCCAAGGGATCCTCGTCGTTGATGATGATCCAGATTTCGGAGAATCCCTTTTCGATATTCTTGATTAT
CGCGGCTATCGGGTCATCAA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRKHIFIVDDDLDHAESLAEILELQGHDVELAQSGESAIARFAEKDFDLVFMDVKLPVMNGVETFFAFRRLRPQAHVFMM
TGYSVEQLVAEAIDNGALGVLYKPFSANDLLDAVAQVEPRGRILVADDNAILIDQVAPILSAAGYAVEIAHNSLDQLDCD
QLSEIDCMIVDMDRSLLRGMELCVDFKDRLPSLPKLLILGSENDEKAAQFSLLTQGILIKPFDPQTLLHTLDHLLHPQEA
TPNAGSRALA

Sequences:

>Translated_250_residues
MRKHIFIVDDDLDHAESLAEILELQGHDVELAQSGESAIARFAEKDFDLVFMDVKLPVMNGVETFFAFRRLRPQAHVFMM
TGYSVEQLVAEAIDNGALGVLYKPFSANDLLDAVAQVEPRGRILVADDNAILIDQVAPILSAAGYAVEIAHNSLDQLDCD
QLSEIDCMIVDMDRSLLRGMELCVDFKDRLPSLPKLLILGSENDEKAAQFSLLTQGILIKPFDPQTLLHTLDHLLHPQEA
TPNAGSRALA
>Mature_250_residues
MRKHIFIVDDDLDHAESLAEILELQGHDVELAQSGESAIARFAEKDFDLVFMDVKLPVMNGVETFFAFRRLRPQAHVFMM
TGYSVEQLVAEAIDNGALGVLYKPFSANDLLDAVAQVEPRGRILVADDNAILIDQVAPILSAAGYAVEIAHNSLDQLDCD
QLSEIDCMIVDMDRSLLRGMELCVDFKDRLPSLPKLLILGSENDEKAAQFSLLTQGILIKPFDPQTLLHTLDHLLHPQEA
TPNAGSRALA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=106, Percent_Identity=38.6792452830189, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 27620; Mature: 27620

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHIFIVDDDLDHAESLAEILELQGHDVELAQSGESAIARFAEKDFDLVFMDVKLPVMN
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCCEEEEEEECCHHH
GVETFFAFRRLRPQAHVFMMTGYSVEQLVAEAIDNGALGVLYKPFSANDLLDAVAQVEPR
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCC
GRILVADDNAILIDQVAPILSAAGYAVEIAHNSLDQLDCDQLSEIDCMIVDMDRSLLRGM
CEEEEECCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCEEEEECCHHHHHHH
ELCVDFKDRLPSLPKLLILGSENDEKAAQFSLLTQGILIKPFDPQTLLHTLDHLLHPQEA
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCC
TPNAGSRALA
CCCCCCCCCC
>Mature Secondary Structure
MRKHIFIVDDDLDHAESLAEILELQGHDVELAQSGESAIARFAEKDFDLVFMDVKLPVMN
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCCEEEEEEECCHHH
GVETFFAFRRLRPQAHVFMMTGYSVEQLVAEAIDNGALGVLYKPFSANDLLDAVAQVEPR
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCC
GRILVADDNAILIDQVAPILSAAGYAVEIAHNSLDQLDCDQLSEIDCMIVDMDRSLLRGM
CEEEEECCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCCEEEEECCHHHHHHH
ELCVDFKDRLPSLPKLLILGSENDEKAAQFSLLTQGILIKPFDPQTLLHTLDHLLHPQEA
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCC
TPNAGSRALA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]