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The map label for this gene is yccK [H]

Identifier: 182678738

GI number: 182678738

Start: 2000987

End: 2001976

Strand: Direct

Name: yccK [H]

Synonym: Bind_1767

Alternate gene names: 182678738

Gene position: 2000987-2001976 (Clockwise)

Preceding gene: 182678736

Following gene: 182678742

Centisome position: 47.98

GC content: 62.42

Gene sequence:

>990_bases
ATGCGGAAACGGGCACTTGGCAAGAGCGGCCTCGATGTTTCAGCGATCGGCTTCGGCTGCATGGGTCTCAATTTCAGCTA
TAGTCACGCACTGACCAAGGACGAGAGCATTACGCTCATCCGTCAGGCGGTGGAGCGTGGCATCACCTTCTTCGACACGG
CCGAGGTCTACGGACCATTTACCAACGAGGAAATCGTCGGTGAGGCACTGGCGCCGTTCCGCGACCAAGTGGTGATCGCC
ACCAAGTTCGGCTTCAACATCGTGGACGGTAAAATGGCCGGCATGAACAGCCGGCCCGAGCACATTCGCGCGGTCTGCGA
CGCGTCGCTCAAGCGTCTGGGCGTCGAGGTGATCGACCTCTTCTACCAGCACCGTGTCGATCCCAACGTCCCGATCGAGG
ATGTGGCCGGCACCGTCAGGGAGCTGATCTGGGAAGGCAAGGTCAAGCATTTCGGCCTGTCCGAGCCGGGGGCGCAAACC
GTTCGTAGCGCGCATGCGGTGCAGCCGATCACGGCGCTGCAAAATGAATATTCGCTATGGACCCGCGGCCCGGAGACCAA
TGGCATCCTTCGGGCCTGCGAGGAGCTCGGCATTGGCCTCGTCGCCTACAGCCCGCTCGGCAAGGGCTTCCTGACGGGCG
CGATGAGCAAGGACACAACGATCGGCGAGAATGACTTCCGCAAAATCCTGCCGCGTTTCACGCCCGAAGCGATGGAGAAA
AACCAGGCGCTGGTCGACCTCCTGAAGCGCATCGCAGGCGAGAAGAAGGCGACGCCCGCCCAGATTGCGCTCGCCTGGCT
GCTGGCGCAGAAGCCCTGGATCGTGCCGATTCCAGGCACCACCAAACTCCACCGGCTGGAAGAAAATCTCGGCGCAGCCT
CCATCGTGCTGACGGCTGATGATCTCGCCGAGATCGAGCGCGCGGCAGCCGCCATCCCGATCGAAGGTGAGCGCTACCCA
GAGCAGCTAATGGCCACCACCGGCCGCTGA

Upstream 100 bases:

>100_bases
TCACTTCATGCAGTTTATAGCGCCTAATTGATCAACGCCGATCGGCCTATCTTCACGCCAATGCGACGGCAGGATGCCGC
GAAGCGATGGAGTATTGGCA

Downstream 100 bases:

>100_bases
GGCCCCTATCGATCCGGACCAAAGTGTATCAATTTGCAGAAGGAACGGGGCAACTCATATCGCCTTCTTTACAATTCAAA
TAATTCTGCAGGTCTTTGAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRKRALGKSGLDVSAIGFGCMGLNFSYSHALTKDESITLIRQAVERGITFFDTAEVYGPFTNEEIVGEALAPFRDQVVIA
TKFGFNIVDGKMAGMNSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGTVRELIWEGKVKHFGLSEPGAQT
VRSAHAVQPITALQNEYSLWTRGPETNGILRACEELGIGLVAYSPLGKGFLTGAMSKDTTIGENDFRKILPRFTPEAMEK
NQALVDLLKRIAGEKKATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAASIVLTADDLAEIERAAAAIPIEGERYP
EQLMATTGR

Sequences:

>Translated_329_residues
MRKRALGKSGLDVSAIGFGCMGLNFSYSHALTKDESITLIRQAVERGITFFDTAEVYGPFTNEEIVGEALAPFRDQVVIA
TKFGFNIVDGKMAGMNSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGTVRELIWEGKVKHFGLSEPGAQT
VRSAHAVQPITALQNEYSLWTRGPETNGILRACEELGIGLVAYSPLGKGFLTGAMSKDTTIGENDFRKILPRFTPEAMEK
NQALVDLLKRIAGEKKATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAASIVLTADDLAEIERAAAAIPIEGERYP
EQLMATTGR
>Mature_329_residues
MRKRALGKSGLDVSAIGFGCMGLNFSYSHALTKDESITLIRQAVERGITFFDTAEVYGPFTNEEIVGEALAPFRDQVVIA
TKFGFNIVDGKMAGMNSRPEHIRAVCDASLKRLGVEVIDLFYQHRVDPNVPIEDVAGTVRELIWEGKVKHFGLSEPGAQT
VRSAHAVQPITALQNEYSLWTRGPETNGILRACEELGIGLVAYSPLGKGFLTGAMSKDTTIGENDFRKILPRFTPEAMEK
NQALVDLLKRIAGEKKATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAASIVLTADDLAEIERAAAAIPIEGERYP
EQLMATTGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=334, Percent_Identity=26.9461077844311, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI27436969, Length=334, Percent_Identity=26.3473053892216, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI4504825, Length=331, Percent_Identity=26.2839879154079, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI27436962, Length=334, Percent_Identity=26.9461077844311, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436966, Length=334, Percent_Identity=26.9461077844311, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=27.4143302180685, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI223718702, Length=283, Percent_Identity=29.3286219081272, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=29.5620437956204, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI41152114, Length=283, Percent_Identity=27.9151943462898, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=32.4242424242424, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI87081735, Length=334, Percent_Identity=32.9341317365269, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=31.4984709480122, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=29.042904290429, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=29.1066282420749, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=24.9201277955272, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI48994888, Length=288, Percent_Identity=26.3888888888889, Blast_Score=74, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325384, Length=336, Percent_Identity=29.4642857142857, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=25.8258258258258, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=339, Percent_Identity=28.6135693215339, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=26.7326732673267, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=28.2868525896414, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=296, Percent_Identity=26.6891891891892, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640980, Length=343, Percent_Identity=24.198250728863, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45549126, Length=346, Percent_Identity=24.2774566473988, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646155, Length=160, Percent_Identity=33.75, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646159, Length=228, Percent_Identity=27.1929824561404, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35954; Mature: 35954

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRALGKSGLDVSAIGFGCMGLNFSYSHALTKDESITLIRQAVERGITFFDTAEVYGPF
CCCCCCCCCCCCCHHHHHEEECCCCCHHHCCCCCHHHHHHHHHHHCCCEEEEHHHHCCCC
TNEEIVGEALAPFRDQVVIATKFGFNIVDGKMAGMNSRPEHIRAVCDASLKRLGVEVIDL
CCHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FYQHRVDPNVPIEDVAGTVRELIWEGKVKHFGLSEPGAQTVRSAHAVQPITALQNEYSLW
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHE
TRGPETNGILRACEELGIGLVAYSPLGKGFLTGAMSKDTTIGENDFRKILPRFTPEAMEK
ECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHC
NQALVDLLKRIAGEKKATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAASIVLTAD
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEEHH
DLAEIERAAAAIPIEGERYPEQLMATTGR
HHHHHHHHHHCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRKRALGKSGLDVSAIGFGCMGLNFSYSHALTKDESITLIRQAVERGITFFDTAEVYGPF
CCCCCCCCCCCCCHHHHHEEECCCCCHHHCCCCCHHHHHHHHHHHCCCEEEEHHHHCCCC
TNEEIVGEALAPFRDQVVIATKFGFNIVDGKMAGMNSRPEHIRAVCDASLKRLGVEVIDL
CCHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FYQHRVDPNVPIEDVAGTVRELIWEGKVKHFGLSEPGAQTVRSAHAVQPITALQNEYSLW
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHE
TRGPETNGILRACEELGIGLVAYSPLGKGFLTGAMSKDTTIGENDFRKILPRFTPEAMEK
ECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHC
NQALVDLLKRIAGEKKATPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLGAASIVLTAD
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEEHH
DLAEIERAAAAIPIEGERYPEQLMATTGR
HHHHHHHHHHCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]