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The map label for this gene is groES

Identifier: 182678710

GI number: 182678710

Start: 1965380

End: 1965667

Strand: Direct

Name: groES

Synonym: Bind_1737

Alternate gene names: 182678710

Gene position: 1965380-1965667 (Clockwise)

Preceding gene: 182678706

Following gene: 182678711

Centisome position: 47.13

GC content: 57.99

Gene sequence:

>288_bases
ATGACTTTTCGTCCTTTGCACGACCGTGTCGTGGTCAAGCGCCTCGAGAGCGAGGAAAAGACCAAGGGTGGCATCATCAT
TCCCGACAGCGCCAAGGAGAAGCCGCAAGAGGGTGAGATCATCGCCGTCGGACCGGGCGGACGCGACGAGAGCGGCAAGC
TGATCCCCCTCGACGTCAAGGCGGGTGACAAGATTTTGTTCGGCAAATGGTCGGGCACCGAAGTCAAGATTGATGGCCAG
GATCTCCTCATCATGAAGGAGAGCGACATTCTCGGTGTCGTTGGCTGA

Upstream 100 bases:

>100_bases
CATTCATGAGTGCTAACAAGAGACAGCTTCAGTCGGCCAAGCTTCGCGGTGGCGCCTTTCGCATTCGGTGCGTCGCGAAT
TTTTAAGGAAGCATTAAACA

Downstream 100 bases:

>100_bases
GTCCTCCCAAGAGCCTCATCTTTTCTCAATAAATTCCGCGAAAGCGATTCAGGAGTTTCAACATGGCAGCCAAAGACGTC
CGTTTCTCGTCTGATGCCCG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MTFRPLHDRVVVKRLESEEKTKGGIIIPDSAKEKPQEGEIIAVGPGGRDESGKLIPLDVKAGDKILFGKWSGTEVKIDGQ
DLLIMKESDILGVVG

Sequences:

>Translated_95_residues
MTFRPLHDRVVVKRLESEEKTKGGIIIPDSAKEKPQEGEIIAVGPGGRDESGKLIPLDVKAGDKILFGKWSGTEVKIDGQ
DLLIMKESDILGVVG
>Mature_94_residues
TFRPLHDRVVVKRLESEEKTKGGIIIPDSAKEKPQEGEIIAVGPGGRDESGKLIPLDVKAGDKILFGKWSGTEVKIDGQD
LLIMKESDILGVVG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=41.1111111111111, Blast_Score=70, Evalue=3e-13,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=37.7777777777778, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=51.5789473684211, Blast_Score=93, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=44.5652173913043, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=34.8314606741573, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=45.0549450549451, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=37.7777777777778, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_BEII9 (B2ICU3)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832856.1
- GeneID:   6200494
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1737
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10281; Mature: 10150

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRPLHDRVVVKRLESEEKTKGGIIIPDSAKEKPQEGEIIAVGPGGRDESGKLIPLDVK
CCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
AGDKILFGKWSGTEVKIDGQDLLIMKESDILGVVG
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC
>Mature Secondary Structure 
TFRPLHDRVVVKRLESEEKTKGGIIIPDSAKEKPQEGEIIAVGPGGRDESGKLIPLDVK
CCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
AGDKILFGKWSGTEVKIDGQDLLIMKESDILGVVG
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA