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The map label for this gene is lsrR [H]

Identifier: 182678693

GI number: 182678693

Start: 1944057

End: 1945052

Strand: Reverse

Name: lsrR [H]

Synonym: Bind_1720

Alternate gene names: 182678693

Gene position: 1945052-1944057 (Counterclockwise)

Preceding gene: 182678696

Following gene: 182678692

Centisome position: 46.64

GC content: 61.04

Gene sequence:

>996_bases
ATGCAGAAACGGTTGAGTGAGCGCGGGCAGAATATCGAGCAGAAGCACCAGGACCAGAAACGTTTCGATCTCGCGGCGCG
GGCGGCTTGGCTCGCTTATGCGCTTGGCCGGACTCAGGATGAAATCGCGGCGGAATTGAATGTTTCGCGCCAGAACGCGC
AGCGTCTCATCGCGCTCGCCAGCGCGGCCGGCCTCGTCAAATTCCGCCTCGATCATCCGCTCGCCGATTGCATCGCCAAA
GCGCAGAAACTGCGGGATAAATTCAGCCTCAAACATGTCGAGGTCGTCCCCTCGGCGCAAAGCGATGAGGACAATAGGCT
TTCCGTGGGGATCGCCGTGGCCTCCTATATCGAGACTCTTCTCTCGCAGACGGAGCCGCAGATTCTGTGTCTTGGTACCG
GCCGCACCTTACGCTCGGCCGTGCATCAAATGCCCCTGATGGAAAAGCCGAAGCACAAGATCGTATCCCTCATCGGCACG
GTGGGACCCGATGGTCGCGCAAGTCCCTATGATGTCGTCATGCGGCTTGCCGACCGTGTTGGGGCACAATGCTACCCCCT
GCCCATGCCGGTCCTGGCCGATGGCCCTGAAGAACGACGCATGCTCCAGTCCCAGAAGGGTTTGCGCGCCCTTCATGATC
TCGCCGAAGAGGCACGGACATGGATCGTGGGCGTCGGCGACCTTGGATCCCAAGCCTCCCTGCATGTCGATGGATTTATC
ACAGACGAGGAACTTGCCGAATTGCAGGCCAAGGGCGCGGTTGGAGAAATTCTCGGCTGGGCTTTCGATGGGCAAGGTGG
ACCGGTCAAGACCTCGATCCATGACAGGCTGATCGCCGTGGGGCTTGCCACGCCCATCGCCTCGCACCGAACGATTATCG
CGGCGAGCGTCGGCGCGCATAAGATCGCCCCCTTGCTCGGCGCGCTCCGAGGCGGGTTGGTCAATGGCGTGCTCACGGAT
GAGAGGACGGCGCAAACCTTGATCGAAGCGCCTTGA

Upstream 100 bases:

>100_bases
AATGAGGTGCCAAAGCCTATCACATGATCTTGATCTTCCAATCGTTTGGCCCCAAGTGGTGCCCACTTGGGTTCGACGCG
GCAGCAAGGCATGCAAAGCG

Downstream 100 bases:

>100_bases
AAGAGAGAGGGCTTGAAAGAAAGAGGGAAACTCATCAGCCCGAGCTCTTGATCGTGGATCAGGTTTCCCTCTTTCGGCGG
AGCGTGATCAATGCCATTCT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQKRLSERGQNIEQKHQDQKRFDLAARAAWLAYALGRTQDEIAAELNVSRQNAQRLIALASAAGLVKFRLDHPLADCIAK
AQKLRDKFSLKHVEVVPSAQSDEDNRLSVGIAVASYIETLLSQTEPQILCLGTGRTLRSAVHQMPLMEKPKHKIVSLIGT
VGPDGRASPYDVVMRLADRVGAQCYPLPMPVLADGPEERRMLQSQKGLRALHDLAEEARTWIVGVGDLGSQASLHVDGFI
TDEELAELQAKGAVGEILGWAFDGQGGPVKTSIHDRLIAVGLATPIASHRTIIAASVGAHKIAPLLGALRGGLVNGVLTD
ERTAQTLIEAP

Sequences:

>Translated_331_residues
MQKRLSERGQNIEQKHQDQKRFDLAARAAWLAYALGRTQDEIAAELNVSRQNAQRLIALASAAGLVKFRLDHPLADCIAK
AQKLRDKFSLKHVEVVPSAQSDEDNRLSVGIAVASYIETLLSQTEPQILCLGTGRTLRSAVHQMPLMEKPKHKIVSLIGT
VGPDGRASPYDVVMRLADRVGAQCYPLPMPVLADGPEERRMLQSQKGLRALHDLAEEARTWIVGVGDLGSQASLHVDGFI
TDEELAELQAKGAVGEILGWAFDGQGGPVKTSIHDRLIAVGLATPIASHRTIIAASVGAHKIAPLLGALRGGLVNGVLTD
ERTAQTLIEAP
>Mature_331_residues
MQKRLSERGQNIEQKHQDQKRFDLAARAAWLAYALGRTQDEIAAELNVSRQNAQRLIALASAAGLVKFRLDHPLADCIAK
AQKLRDKFSLKHVEVVPSAQSDEDNRLSVGIAVASYIETLLSQTEPQILCLGTGRTLRSAVHQMPLMEKPKHKIVSLIGT
VGPDGRASPYDVVMRLADRVGAQCYPLPMPVLADGPEERRMLQSQKGLRALHDLAEEARTWIVGVGDLGSQASLHVDGFI
TDEELAELQAKGAVGEILGWAFDGQGGPVKTSIHDRLIAVGLATPIASHRTIIAASVGAHKIAPLLGALRGGLVNGVLTD
ERTAQTLIEAP

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=316, Percent_Identity=28.7974683544304, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082414, Length=316, Percent_Identity=26.5822784810127, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35700; Mature: 35700

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRLSERGQNIEQKHQDQKRFDLAARAAWLAYALGRTQDEIAAELNVSRQNAQRLIALA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
SAAGLVKFRLDHPLADCIAKAQKLRDKFSLKHVEVVPSAQSDEDNRLSVGIAVASYIETL
HHHCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHH
LSQTEPQILCLGTGRTLRSAVHQMPLMEKPKHKIVSLIGTVGPDGRASPYDVVMRLADRV
HHCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GAQCYPLPMPVLADGPEERRMLQSQKGLRALHDLAEEARTWIVGVGDLGSQASLHVDGFI
CCEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCC
TDEELAELQAKGAVGEILGWAFDGQGGPVKTSIHDRLIAVGLATPIASHRTIIAASVGAH
CHHHHHHHHHCCCHHHHHHEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
KIAPLLGALRGGLVNGVLTDERTAQTLIEAP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MQKRLSERGQNIEQKHQDQKRFDLAARAAWLAYALGRTQDEIAAELNVSRQNAQRLIALA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
SAAGLVKFRLDHPLADCIAKAQKLRDKFSLKHVEVVPSAQSDEDNRLSVGIAVASYIETL
HHHCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHH
LSQTEPQILCLGTGRTLRSAVHQMPLMEKPKHKIVSLIGTVGPDGRASPYDVVMRLADRV
HHCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GAQCYPLPMPVLADGPEERRMLQSQKGLRALHDLAEEARTWIVGVGDLGSQASLHVDGFI
CCEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCC
TDEELAELQAKGAVGEILGWAFDGQGGPVKTSIHDRLIAVGLATPIASHRTIIAASVGAH
CHHHHHHHHHCCCHHHHHHEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHH
KIAPLLGALRGGLVNGVLTDERTAQTLIEAP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA