Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 182678688

GI number: 182678688

Start: 1935404

End: 1935883

Strand: Direct

Name: moaE [H]

Synonym: Bind_1715

Alternate gene names: 182678688

Gene position: 1935404-1935883 (Clockwise)

Preceding gene: 182678687

Following gene: 182678689

Centisome position: 46.41

GC content: 58.33

Gene sequence:

>480_bases
TTGAGCGGCCAGACCATCGTCAAAATTCAAAAAGAAATTTTCGACCCCGTACAGGAATGCCTGCCCCTGACGCAAGACCG
CAAGGATCTTGGCGCGCTCGTGACCTTCACCGGCCTTTGCCGCGACGAGGGAGGCGTCCTGCAGTCTCTCGAAATCGAGC
ATTATCCGGGTATGGCGGAAGAGGAAATCGGCCGAATTATCACCGAGGCCCGCCGCCGCTGGCCGATCGAGGACGTGGTG
GTGATCCATCGATTCGGCATGATCACGCCGGGCGAGCCGATCGTCCTCGTAGCCGCCACGGGGCTGCATCGCGCCGAAGC
TTTCGAGGCGACGAATTTCCTCATGGATTTTCTCAAAACCGAGGCGCCATTCTGGAAAAAGCAGCATCTCCATGTGGATG
GTGCAGGCGGTTGGGTCAGCGCCAAGCAGGAAGATGAAGCAGCCGCGCAAAAATGGCTGCAAACCCAATCTCCGAGCTAA

Upstream 100 bases:

>100_bases
ATCCGGGCCGCCCTGGACCATGTTCACGCCAAGCCCGACGCCATGATCGGCAACGCTCACGAAGTCGCCTTCTTTCCTCC
CATGACTGGAGGCTAAGCAT

Downstream 100 bases:

>100_bases
TTCTCCTTCAAAAACCAGTGACCGGTGATCAAGCCAGCCTGATACAGGCTCTGGACCCATTGCAGGTTCATCCATTGGGT
TTTGAAAACTTCATAAGCAC

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSGQTIVKIQKEIFDPVQECLPLTQDRKDLGALVTFTGLCRDEGGVLQSLEIEHYPGMAEEEIGRIITEARRRWPIEDVV
VIHRFGMITPGEPIVLVAATGLHRAEAFEATNFLMDFLKTEAPFWKKQHLHVDGAGGWVSAKQEDEAAAQKWLQTQSPS

Sequences:

>Translated_159_residues
MSGQTIVKIQKEIFDPVQECLPLTQDRKDLGALVTFTGLCRDEGGVLQSLEIEHYPGMAEEEIGRIITEARRRWPIEDVV
VIHRFGMITPGEPIVLVAATGLHRAEAFEATNFLMDFLKTEAPFWKKQHLHVDGAGGWVSAKQEDEAAAQKWLQTQSPS
>Mature_158_residues
SGQTIVKIQKEIFDPVQECLPLTQDRKDLGALVTFTGLCRDEGGVLQSLEIEHYPGMAEEEIGRIITEARRRWPIEDVVV
IHRFGMITPGEPIVLVAATGLHRAEAFEATNFLMDFLKTEAPFWKKQHLHVDGAGGWVSAKQEDEAAAQKWLQTQSPS

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=100, Percent_Identity=38, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1787003, Length=138, Percent_Identity=46.3768115942029, Blast_Score=130, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21356259, Length=116, Percent_Identity=36.2068965517241, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17797; Mature: 17665

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQTIVKIQKEIFDPVQECLPLTQDRKDLGALVTFTGLCRDEGGVLQSLEIEHYPGMAE
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
EEIGRIITEARRRWPIEDVVVIHRFGMITPGEPIVLVAATGLHRAEAFEATNFLMDFLKT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
EAPFWKKQHLHVDGAGGWVSAKQEDEAAAQKWLQTQSPS
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGQTIVKIQKEIFDPVQECLPLTQDRKDLGALVTFTGLCRDEGGVLQSLEIEHYPGMAE
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCH
EEIGRIITEARRRWPIEDVVVIHRFGMITPGEPIVLVAATGLHRAEAFEATNFLMDFLKT
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
EAPFWKKQHLHVDGAGGWVSAKQEDEAAAQKWLQTQSPS
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]