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The map label for this gene is ptrB [H]

Identifier: 182678618

GI number: 182678618

Start: 1857557

End: 1859662

Strand: Direct

Name: ptrB [H]

Synonym: Bind_1644

Alternate gene names: 182678618

Gene position: 1857557-1859662 (Clockwise)

Preceding gene: 182678617

Following gene: 182678620

Centisome position: 44.54

GC content: 58.26

Gene sequence:

>2106_bases
ATGGATAAGACCTTAGCCGTCCCGCCCGTCCCTCCCCTCGTCGAGAAGCGGCCAGAATCGAAAACCGTCCATGGCGTGAC
GTTGGTCGATGATTATGCTTGGCTCAAAGCTGACAATTGGCAGCAAGTCCTGCGTGATCCTTCCGCTCTGCCAGCCGATA
TTCGGCAAGTGCTCGAGGGTGAAAATCTCTATGCGCAGGCCCTGTTGGCGCCTGGCGAAGAGTTACGCCAAACCCTCGTC
AAGGAAATGCGCGGACGCATCAAGGAGGACGATGCCGAAGTCCCTACGAAGGATGGTGACTGGCTCTACTATGCCCGCCA
TGTAACGGGAGGACAGCATCCTTTGTTCTGCCGCACCGATCTTACTGGGGAGAACGAAGTGGTTCTCCTTGATGGCGAAA
AAGAAGGACACGGCAAGGCTTTCTTCGACATCGGCATGGTGCGTCATTCCCCCGATCACCGCCTCGTGGCCTGGAGCGTC
GACGAAAAGGGCTCGGAACTCTATTCGATCAGAGTACGTGATCCGGCGACAGGGACGGATGGGCCAGATCTCGTGCCCGA
TACTGACGGCAATCTGGTCTGGATGCGGGATTCGAGCGGCTTCTATTACGTTCGCGTCGATGCCAATCATCGGACGGCTC
AAGTCTTTCGCCATATCGTCGGAACCGATAGCGCCAAAGATGTTCTGGTGTTCGAGGAGCTCGATCCTGCTTGGTTCGTC
AATATCCGGCGCAGCCAGTCCTCGACATTCGCGATCGTCAGCGTTTCCGATCACGATTCCTCGGAATGCCACCTTCTCGA
TCTCGGCGATCCGCTCGCTGCTCCACAATTGATTGAGGCCCGCGCCCGTGGCTTGCGTTATGAGGTGGAAGATCATGGGG
ACCGGCTGTTCATCCGCACCAACGCGGATGGCGCCGAGGATTTCAAGATCGTCAGCGCTCCGCTTGCGACGCCATCCAAG
GCCTATTGGCAGGATTTTGTGGCCCATGTCGCGGGGCGGATGATCATCACCTGCGCCATATTCAAGGATTATCTCGTCCG
TCTCGAGCGCGAGAATGGTCTGCCGAGCCTCAAGATCCATGAATTCGTGACCGGGACCGAGCGAACGGTCGCCTTTGCCG
AAGAGGCCTATCACCTGGGGCTCGCGGAACGCTTCGAATACGCGACGACGCTTCTCCGCTTTACCTATTCCTCGATGACC
ACGCCGCGAGAAATCTATGATTATGATCTCGCGACCGAAGCCCGCGTCTTGCGGAAGCGTCAGATCCTGCCGAGCGGCCA
TGATCCTGCCGATTACGTGACCAAGCGGCTGTTCGCTACGGCTGCGGACGGAGCCAGCGTCCCGGTCTCAATCCTCTACC
ATAAAAACACCAAGCTCGACGGTTCCGCCCCCGTGCTGCTCTACGGCTATGGCGCTTACGGCCATCCAACGCCGGCTTCT
TTCTCCTCTGGCCGGCTCAGTCTGGTCGATCGCGGGTTCATATTCGCGATCGCTCATATTCGCGGCGGCACTGACAAGGG
GTGGCACTGGTATACGGACGGCAAACTCGACAAAAAAACCAATACGTTTGCGGATTTTGTCACGGCGGGACGGCATCTCG
TTGCACAAGGGTTGACTCGCGAAGGACGCATCGTTGCCCAAGGTGGCAGCGCCGGCGGCATGCTGATGGGCGCGGTCGCC
AATCTGGCACCCGAGCTTTTTGCCGGCATTATCGCGGATGTGCCCTTCGTCGATGTTTTGAATACGATGCTCGACGCCGA
ATTGCCGCTGACCCCGCCAGAATGGCTCGAATGGGGCAATCCGATCCTTGATCCACAGGCCTTTGCCACCATTCGTAGCT
ATTCGCCTTACGATAATGTCGCAGCTAAAATCTATCCGCCAATTTTAGCCCTGGGCGGGCTGACCGATCCCCGCGTCACC
TATTGGGAGCCGGCCAAATGGGTCGCCCGCTTGCGGGCGACAATGGCAGGGGGCGGTCCCATTCTCCTGATGACCAATAT
GGGCGCAGGCCATGGCGGCGCATCGGGTCGATTCGACCGGTTGAGCGAGGTCGCAAATGAATACGCCTTCGCCTTGGCCT
GTATTGATCCCGGTTTTACGTCTTAG

Upstream 100 bases:

>100_bases
GATGCCGGCTCATCCTCCTGACTGGGCAATTTTCAGGACATTGCTGCCTTGCGTTGCGATAAACACAAGGCAGCTCACAT
GAAATGACGAACGACAGAAC

Downstream 100 bases:

>100_bases
AGCCTTGGATTTTCATTGAAAATGCATCAGGCCCAAAAGGGGAAGCCCCTTTTGGGCCTGATGCTCTAAGCGTAAAACCG
GGCAGGAAAGCCTGAAAATT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MDKTLAVPPVPPLVEKRPESKTVHGVTLVDDYAWLKADNWQQVLRDPSALPADIRQVLEGENLYAQALLAPGEELRQTLV
KEMRGRIKEDDAEVPTKDGDWLYYARHVTGGQHPLFCRTDLTGENEVVLLDGEKEGHGKAFFDIGMVRHSPDHRLVAWSV
DEKGSELYSIRVRDPATGTDGPDLVPDTDGNLVWMRDSSGFYYVRVDANHRTAQVFRHIVGTDSAKDVLVFEELDPAWFV
NIRRSQSSTFAIVSVSDHDSSECHLLDLGDPLAAPQLIEARARGLRYEVEDHGDRLFIRTNADGAEDFKIVSAPLATPSK
AYWQDFVAHVAGRMIITCAIFKDYLVRLERENGLPSLKIHEFVTGTERTVAFAEEAYHLGLAERFEYATTLLRFTYSSMT
TPREIYDYDLATEARVLRKRQILPSGHDPADYVTKRLFATAADGASVPVSILYHKNTKLDGSAPVLLYGYGAYGHPTPAS
FSSGRLSLVDRGFIFAIAHIRGGTDKGWHWYTDGKLDKKTNTFADFVTAGRHLVAQGLTREGRIVAQGGSAGGMLMGAVA
NLAPELFAGIIADVPFVDVLNTMLDAELPLTPPEWLEWGNPILDPQAFATIRSYSPYDNVAAKIYPPILALGGLTDPRVT
YWEPAKWVARLRATMAGGGPILLMTNMGAGHGGASGRFDRLSEVANEYAFALACIDPGFTS

Sequences:

>Translated_701_residues
MDKTLAVPPVPPLVEKRPESKTVHGVTLVDDYAWLKADNWQQVLRDPSALPADIRQVLEGENLYAQALLAPGEELRQTLV
KEMRGRIKEDDAEVPTKDGDWLYYARHVTGGQHPLFCRTDLTGENEVVLLDGEKEGHGKAFFDIGMVRHSPDHRLVAWSV
DEKGSELYSIRVRDPATGTDGPDLVPDTDGNLVWMRDSSGFYYVRVDANHRTAQVFRHIVGTDSAKDVLVFEELDPAWFV
NIRRSQSSTFAIVSVSDHDSSECHLLDLGDPLAAPQLIEARARGLRYEVEDHGDRLFIRTNADGAEDFKIVSAPLATPSK
AYWQDFVAHVAGRMIITCAIFKDYLVRLERENGLPSLKIHEFVTGTERTVAFAEEAYHLGLAERFEYATTLLRFTYSSMT
TPREIYDYDLATEARVLRKRQILPSGHDPADYVTKRLFATAADGASVPVSILYHKNTKLDGSAPVLLYGYGAYGHPTPAS
FSSGRLSLVDRGFIFAIAHIRGGTDKGWHWYTDGKLDKKTNTFADFVTAGRHLVAQGLTREGRIVAQGGSAGGMLMGAVA
NLAPELFAGIIADVPFVDVLNTMLDAELPLTPPEWLEWGNPILDPQAFATIRSYSPYDNVAAKIYPPILALGGLTDPRVT
YWEPAKWVARLRATMAGGGPILLMTNMGAGHGGASGRFDRLSEVANEYAFALACIDPGFTS
>Mature_701_residues
MDKTLAVPPVPPLVEKRPESKTVHGVTLVDDYAWLKADNWQQVLRDPSALPADIRQVLEGENLYAQALLAPGEELRQTLV
KEMRGRIKEDDAEVPTKDGDWLYYARHVTGGQHPLFCRTDLTGENEVVLLDGEKEGHGKAFFDIGMVRHSPDHRLVAWSV
DEKGSELYSIRVRDPATGTDGPDLVPDTDGNLVWMRDSSGFYYVRVDANHRTAQVFRHIVGTDSAKDVLVFEELDPAWFV
NIRRSQSSTFAIVSVSDHDSSECHLLDLGDPLAAPQLIEARARGLRYEVEDHGDRLFIRTNADGAEDFKIVSAPLATPSK
AYWQDFVAHVAGRMIITCAIFKDYLVRLERENGLPSLKIHEFVTGTERTVAFAEEAYHLGLAERFEYATTLLRFTYSSMT
TPREIYDYDLATEARVLRKRQILPSGHDPADYVTKRLFATAADGASVPVSILYHKNTKLDGSAPVLLYGYGAYGHPTPAS
FSSGRLSLVDRGFIFAIAHIRGGTDKGWHWYTDGKLDKKTNTFADFVTAGRHLVAQGLTREGRIVAQGGSAGGMLMGAVA
NLAPELFAGIIADVPFVDVLNTMLDAELPLTPPEWLEWGNPILDPQAFATIRSYSPYDNVAAKIYPPILALGGLTDPRVT
YWEPAKWVARLRATMAGGGPILLMTNMGAGHGGASGRFDRLSEVANEYAFALACIDPGFTS

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=543, Percent_Identity=29.2817679558011, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI284172413, Length=543, Percent_Identity=29.2817679558011, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI70778815, Length=543, Percent_Identity=29.2817679558011, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI284172438, Length=543, Percent_Identity=29.097605893186, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI284172431, Length=543, Percent_Identity=29.097605893186, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI41349456, Length=733, Percent_Identity=24.6930422919509, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI108860686, Length=268, Percent_Identity=35.4477611940299, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI108860692, Length=217, Percent_Identity=36.8663594470046, Blast_Score=142, Evalue=1e-33,
Organism=Escherichia coli, GI1788150, Length=688, Percent_Identity=37.3546511627907, Blast_Score=445, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24583414, Length=734, Percent_Identity=24.6594005449591, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI221510989, Length=717, Percent_Identity=24.2677824267782, Blast_Score=178, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77335; Mature: 77335

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTLAVPPVPPLVEKRPESKTVHGVTLVDDYAWLKADNWQQVLRDPSALPADIRQVLEG
CCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEECCCCHHHHHCCCCCCCHHHHHHHCC
ENLYAQALLAPGEELRQTLVKEMRGRIKEDDAEVPTKDGDWLYYARHVTGGQHPLFCRTD
CCCEEHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEC
LTGENEVVLLDGEKEGHGKAFFDIGMVRHSPDHRLVAWSVDEKGSELYSIRVRDPATGTD
CCCCCCEEEEECCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCCC
GPDLVPDTDGNLVWMRDSSGFYYVRVDANHRTAQVFRHIVGTDSAKDVLVFEELDPAWFV
CCCCCCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
NIRRSQSSTFAIVSVSDHDSSECHLLDLGDPLAAPQLIEARARGLRYEVEDHGDRLFIRT
EEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCEEEEEE
NADGAEDFKIVSAPLATPSKAYWQDFVAHVAGRMIITCAIFKDYLVRLERENGLPSLKIH
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEE
EFVTGTERTVAFAEEAYHLGLAERFEYATTLLRFTYSSMTTPREIYDYDLATEARVLRKR
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHH
QILPSGHDPADYVTKRLFATAADGASVPVSILYHKNTKLDGSAPVLLYGYGAYGHPTPAS
HCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCC
FSSGRLSLVDRGFIFAIAHIRGGTDKGWHWYTDGKLDKKTNTFADFVTAGRHLVAQGLTR
CCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCC
EGRIVAQGGSAGGMLMGAVANLAPELFAGIIADVPFVDVLNTMLDAELPLTPPEWLEWGN
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHCCC
PILDPQAFATIRSYSPYDNVAAKIYPPILALGGLTDPRVTYWEPAKWVARLRATMAGGGP
CCCCCHHHHHHHCCCCCCCCHHHHCCHHHEECCCCCCCEEEECHHHHHHHHHHHHCCCCC
ILLMTNMGAGHGGASGRFDRLSEVANEYAFALACIDPGFTS
EEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCC
>Mature Secondary Structure
MDKTLAVPPVPPLVEKRPESKTVHGVTLVDDYAWLKADNWQQVLRDPSALPADIRQVLEG
CCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEECCCCHHHHHCCCCCCCHHHHHHHCC
ENLYAQALLAPGEELRQTLVKEMRGRIKEDDAEVPTKDGDWLYYARHVTGGQHPLFCRTD
CCCEEHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEC
LTGENEVVLLDGEKEGHGKAFFDIGMVRHSPDHRLVAWSVDEKGSELYSIRVRDPATGTD
CCCCCCEEEEECCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCCC
GPDLVPDTDGNLVWMRDSSGFYYVRVDANHRTAQVFRHIVGTDSAKDVLVFEELDPAWFV
CCCCCCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
NIRRSQSSTFAIVSVSDHDSSECHLLDLGDPLAAPQLIEARARGLRYEVEDHGDRLFIRT
EEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCEEEEEE
NADGAEDFKIVSAPLATPSKAYWQDFVAHVAGRMIITCAIFKDYLVRLERENGLPSLKIH
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCEEEE
EFVTGTERTVAFAEEAYHLGLAERFEYATTLLRFTYSSMTTPREIYDYDLATEARVLRKR
HHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHH
QILPSGHDPADYVTKRLFATAADGASVPVSILYHKNTKLDGSAPVLLYGYGAYGHPTPAS
HCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCC
FSSGRLSLVDRGFIFAIAHIRGGTDKGWHWYTDGKLDKKTNTFADFVTAGRHLVAQGLTR
CCCCCEEEEECCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCC
EGRIVAQGGSAGGMLMGAVANLAPELFAGIIADVPFVDVLNTMLDAELPLTPPEWLEWGN
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHCCC
PILDPQAFATIRSYSPYDNVAAKIYPPILALGGLTDPRVTYWEPAKWVARLRATMAGGGP
CCCCCHHHHHHHCCCCCCCCHHHHCCHHHEECCCCCCCEEEECHHHHHHHHHHHHCCCCC
ILLMTNMGAGHGGASGRFDRLSEVANEYAFALACIDPGFTS
EEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]