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The map label for this gene is msrB1 [H]

Identifier: 182678617

GI number: 182678617

Start: 1856920

End: 1857360

Strand: Direct

Name: msrB1 [H]

Synonym: Bind_1643

Alternate gene names: 182678617

Gene position: 1856920-1857360 (Clockwise)

Preceding gene: 182678615

Following gene: 182678618

Centisome position: 44.53

GC content: 52.38

Gene sequence:

>441_bases
ATGATCGACGCCGAGGAGGGTGTCATGACGCAAGACAATTCTAAAAGCAAGATAACGAAAAGCGATGCTGAATGGCGCGC
TCAATTGACGCCGTCTCAATACGAGGTCACGCGTCGACACGGAACCGAGCAAGCCTTTACTGGACCAAATTGGGATCAAA
AAAAACCAGGTCTTTACTCCTGTATTTGTTGCGGTGCACCTTTATTCCAGTCGGAGACCAAGTTTGATTCCGGAACCGGC
TGGCCGAGTTTCTATGCGCCCGTGCAAGCTGGCGCCGTCGAGGAACATGCGGATAATTCGCATTTCATGCATCGCACCGA
GGTCCGCTGCGCGAAATGCGAGGCTCATCTTGGCCATGTCTTTCCCGATGGACCGCAGCCCACCGGTTTGCGCTATTGCA
TGAATGGCCAATCGCTTAAATTCGAGCCTACGGACAAATAA

Upstream 100 bases:

>100_bases
TCGATGCTGCACTGTGCCTTCTTGCTCCTATATAGGTCAGTCCAATGATAAAAAAAGCCTCGACCATGCAAAGCTTGCCG
AATTCCTTGGCGAGTGAATA

Downstream 100 bases:

>100_bases
AGCCTCTCGAAATCGGTGCATGAGCGTCCCCAGTACAGCTAGAGAATACATTCAAAGATTTAATTTGGGTCTATTTCAGG
CACTCTCGCTAAGCTCGATG

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 1 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MIDAEEGVMTQDNSKSKITKSDAEWRAQLTPSQYEVTRRHGTEQAFTGPNWDQKKPGLYSCICCGAPLFQSETKFDSGTG
WPSFYAPVQAGAVEEHADNSHFMHRTEVRCAKCEAHLGHVFPDGPQPTGLRYCMNGQSLKFEPTDK

Sequences:

>Translated_146_residues
MIDAEEGVMTQDNSKSKITKSDAEWRAQLTPSQYEVTRRHGTEQAFTGPNWDQKKPGLYSCICCGAPLFQSETKFDSGTG
WPSFYAPVQAGAVEEHADNSHFMHRTEVRCAKCEAHLGHVFPDGPQPTGLRYCMNGQSLKFEPTDK
>Mature_146_residues
MIDAEEGVMTQDNSKSKITKSDAEWRAQLTPSQYEVTRRHGTEQAFTGPNWDQKKPGLYSCICCGAPLFQSETKFDSGTG
WPSFYAPVQAGAVEEHADNSHFMHRTEVRCAKCEAHLGHVFPDGPQPTGLRYCMNGQSLKFEPTDK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=135, Percent_Identity=51.8518518518518, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI301336162, Length=135, Percent_Identity=51.8518518518518, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI73089054, Length=135, Percent_Identity=51.8518518518518, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI37620216, Length=135, Percent_Identity=51.8518518518518, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=51.5384615384615, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=55.3719008264463, Blast_Score=147, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI115532676, Length=139, Percent_Identity=46.7625899280576, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17553450, Length=139, Percent_Identity=46.7625899280576, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=144, Percent_Identity=40.2777777777778, Blast_Score=102, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645799, Length=137, Percent_Identity=50.3649635036496, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI45553335, Length=135, Percent_Identity=50.3703703703704, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI21356369, Length=135, Percent_Identity=50.3703703703704, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24645801, Length=148, Percent_Identity=47.2972972972973, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24645804, Length=146, Percent_Identity=47.2602739726027, Blast_Score=132, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221378664, Length=131, Percent_Identity=49.618320610687, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221378662, Length=138, Percent_Identity=47.1014492753623, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16301; Mature: 16301

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAEEGVMTQDNSKSKITKSDAEWRAQLTPSQYEVTRRHGTEQAFTGPNWDQKKPGLYS
CCCCCCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEE
CICCGAPLFQSETKFDSGTGWPSFYAPVQAGAVEEHADNSHFMHRTEVRCAKCEAHLGHV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCC
FPDGPQPTGLRYCMNGQSLKFEPTDK
CCCCCCCCCEEEEECCCEEECCCCCC
>Mature Secondary Structure
MIDAEEGVMTQDNSKSKITKSDAEWRAQLTPSQYEVTRRHGTEQAFTGPNWDQKKPGLYS
CCCCCCCCCCCCCCCCCEECCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEE
CICCGAPLFQSETKFDSGTGWPSFYAPVQAGAVEEHADNSHFMHRTEVRCAKCEAHLGHV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCC
FPDGPQPTGLRYCMNGQSLKFEPTDK
CCCCCCCCCEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]