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The map label for this gene is dacC [H]

Identifier: 182678513

GI number: 182678513

Start: 1740910

End: 1742094

Strand: Reverse

Name: dacC [H]

Synonym: Bind_1537

Alternate gene names: 182678513

Gene position: 1742094-1740910 (Counterclockwise)

Preceding gene: 182678514

Following gene: 182678512

Centisome position: 41.78

GC content: 60.51

Gene sequence:

>1185_bases
GTGGTCCCCGTCTCGCGCCGCATTCTCCTGATCCCGTTTTTGCTCTCGGGCTTTCTTGCTGGCCCGATCGCGGCCAGGGC
GCAAGGCATCGACACCAGCGCCCCCAATGTCATCCTCATCGAGGCTGAAACCGGCGGCGTTCTCTTCGAGAAGAACCCCG
ACGCGCCGGTGATACCGGCGTCCACGGCCAAGATCATGACCGCCGAACTGGTCTTCCAAAACCTGCGGGAAGGCCGAATT
CATCTCGACGACACCTTTCTCATCAGCGAAACCGCCTGGCGCCAGGGTGGCGCGCCCTCGCGCGGATCGAGCATGTATGC
CGCCCTCAACAGCCACGTTCGCGTCGAGGATCTCATCCGCGGCCTCGTCATCGACTCGGGCAATGATGCCGCCATAGCGC
TGGCAGAGGGGCTGGCCGGTTCTGAGGGGGCCTTCGCGACCTTGATGACGAAACGGGCGCGCGAACTCGGCCTTGATCAT
TCCGTCTTCACCAATGCCTGGGGCAGGGGCGATCCCGACCAATTGGTGACGGCGCGCGACATGGCGCGCCTCGCCGCTCA
TGTGATCACCACTTATCCCGATTATTATAAATATTTCGGCGAGAAGGAATTCACCTGGAACAAGATCCGGCAGACCAATC
GCAATCCCTTGCTCACGATGGATTTCGGTGCCGATGGCCTGAAAACCGGTAACATCGACGCCAGCGGCTATGGTCTCGTC
GGATCCGCCGTGCAGAACGGCGAGCGGCTTATCCTGGCCCTTTACGGCGCAAAAAACGCCAAGGAACGCGCCGATGAGGC
AAGACGATTGTTCCTCTGGGGCTTTCGGTCTTTCACGACGAAGACCGTCTACAAGGCCAATGAGACGATTGGAACCGCAC
GGGTTTTTGGGGGCGCCAAAACCGATGTCGATCTTGTCGCCCATCGTGATATCAAGCTTTTGATCCCGCATCTGGGCGGC
GAGAAATTCACCGGCAAGATTGTCTATACAGGTCCCTTGCCGGCCCCGGTCGAAGAGGGGCAGCAAGTCGGGCAATTGAT
CATCCGGCGCGGCACGCTCGACGCGCTCGAAATACCGCTCTATACCGCCGAAGCGGTTCCACAGGGCCCCTTGCCGCGCC
GGGCACTCGATGCCGGATATGAAGCCGGCGTGCTGTTGTGGCGCAAATATATGACCAAGCCATGA

Upstream 100 bases:

>100_bases
TTGGGTTTGATACGTTTATAAGACATAGAGCATCACTCACGCGTCCTGCTCAACGAGCGATGCTCTAGCATTTTCGCTGC
TCCAGCACAGGAGATCGCTC

Downstream 100 bases:

>100_bases
GTATTCCTTCCGAGCGTGCCGCTTCCGAACACATTGTGGAAAATCCCGTCCCCACACGCGGATTCTTCATCACTCTGGAA
GGGGGAGAAGGAACCGGAAA

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MVPVSRRILLIPFLLSGFLAGPIAARAQGIDTSAPNVILIEAETGGVLFEKNPDAPVIPASTAKIMTAELVFQNLREGRI
HLDDTFLISETAWRQGGAPSRGSSMYAALNSHVRVEDLIRGLVIDSGNDAAIALAEGLAGSEGAFATLMTKRARELGLDH
SVFTNAWGRGDPDQLVTARDMARLAAHVITTYPDYYKYFGEKEFTWNKIRQTNRNPLLTMDFGADGLKTGNIDASGYGLV
GSAVQNGERLILALYGAKNAKERADEARRLFLWGFRSFTTKTVYKANETIGTARVFGGAKTDVDLVAHRDIKLLIPHLGG
EKFTGKIVYTGPLPAPVEEGQQVGQLIIRRGTLDALEIPLYTAEAVPQGPLPRRALDAGYEAGVLLWRKYMTKP

Sequences:

>Translated_394_residues
MVPVSRRILLIPFLLSGFLAGPIAARAQGIDTSAPNVILIEAETGGVLFEKNPDAPVIPASTAKIMTAELVFQNLREGRI
HLDDTFLISETAWRQGGAPSRGSSMYAALNSHVRVEDLIRGLVIDSGNDAAIALAEGLAGSEGAFATLMTKRARELGLDH
SVFTNAWGRGDPDQLVTARDMARLAAHVITTYPDYYKYFGEKEFTWNKIRQTNRNPLLTMDFGADGLKTGNIDASGYGLV
GSAVQNGERLILALYGAKNAKERADEARRLFLWGFRSFTTKTVYKANETIGTARVFGGAKTDVDLVAHRDIKLLIPHLGG
EKFTGKIVYTGPLPAPVEEGQQVGQLIIRRGTLDALEIPLYTAEAVPQGPLPRRALDAGYEAGVLLWRKYMTKP
>Mature_394_residues
MVPVSRRILLIPFLLSGFLAGPIAARAQGIDTSAPNVILIEAETGGVLFEKNPDAPVIPASTAKIMTAELVFQNLREGRI
HLDDTFLISETAWRQGGAPSRGSSMYAALNSHVRVEDLIRGLVIDSGNDAAIALAEGLAGSEGAFATLMTKRARELGLDH
SVFTNAWGRGDPDQLVTARDMARLAAHVITTYPDYYKYFGEKEFTWNKIRQTNRNPLLTMDFGADGLKTGNIDASGYGLV
GSAVQNGERLILALYGAKNAKERADEARRLFLWGFRSFTTKTVYKANETIGTARVFGGAKTDVDLVAHRDIKLLIPHLGG
EKFTGKIVYTGPLPAPVEEGQQVGQLIIRRGTLDALEIPLYTAEAVPQGPLPRRALDAGYEAGVLLWRKYMTKP

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=368, Percent_Identity=39.945652173913, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI87082022, Length=374, Percent_Identity=35.0267379679144, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786851, Length=387, Percent_Identity=33.8501291989664, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87082054, Length=250, Percent_Identity=27.2, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42823; Mature: 42823

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVSRRILLIPFLLSGFLAGPIAARAQGIDTSAPNVILIEAETGGVLFEKNPDAPVIPA
CCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCC
STAKIMTAELVFQNLREGRIHLDDTFLISETAWRQGGAPSRGSSMYAALNSHVRVEDLIR
CHHHHHHHHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHH
GLVIDSGNDAAIALAEGLAGSEGAFATLMTKRARELGLDHSVFTNAWGRGDPDQLVTARD
EEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHH
MARLAAHVITTYPDYYKYFGEKEFTWNKIRQTNRNPLLTMDFGADGLKTGNIDASGYGLV
HHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCEE
GSAVQNGERLILALYGAKNAKERADEARRLFLWGFRSFTTKTVYKANETIGTARVFGGAK
CHHHCCCCEEEEEEECCCCHHHHHHHHHEEEEEEHHHHHHHEEEECCCCCCCCEECCCCC
TDVDLVAHRDIKLLIPHLGGEKFTGKIVYTGPLPAPVEEGQQVGQLIIRRGTLDALEIPL
CCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECCE
YTAEAVPQGPLPRRALDAGYEAGVLLWRKYMTKP
EECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPVSRRILLIPFLLSGFLAGPIAARAQGIDTSAPNVILIEAETGGVLFEKNPDAPVIPA
CCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCC
STAKIMTAELVFQNLREGRIHLDDTFLISETAWRQGGAPSRGSSMYAALNSHVRVEDLIR
CHHHHHHHHHHHHHHHCCCEEECCEEEEEHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHH
GLVIDSGNDAAIALAEGLAGSEGAFATLMTKRARELGLDHSVFTNAWGRGDPDQLVTARD
EEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHH
MARLAAHVITTYPDYYKYFGEKEFTWNKIRQTNRNPLLTMDFGADGLKTGNIDASGYGLV
HHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCEE
GSAVQNGERLILALYGAKNAKERADEARRLFLWGFRSFTTKTVYKANETIGTARVFGGAK
CHHHCCCCEEEEEEECCCCHHHHHHHHHEEEEEEHHHHHHHEEEECCCCCCCCEECCCCC
TDVDLVAHRDIKLLIPHLGGEKFTGKIVYTGPLPAPVEEGQQVGQLIIRRGTLDALEIPL
CCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECCE
YTAEAVPQGPLPRRALDAGYEAGVLLWRKYMTKP
EECCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]