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The map label for this gene is moaC

Identifier: 182678400

GI number: 182678400

Start: 1629792

End: 1630274

Strand: Direct

Name: moaC

Synonym: Bind_1417

Alternate gene names: 182678400

Gene position: 1629792-1630274 (Clockwise)

Preceding gene: 182678399

Following gene: 182678401

Centisome position: 39.08

GC content: 57.76

Gene sequence:

>483_bases
ATGAGTTCCTTGACCCATCTGACGAGCCATGGCGAAGCCGTCATGGTCGATGTCTCCGATAAGGCAGAGACCGAGCGGGT
CGCGATCGCCGAGGCCCGGGTCGTCATGCGTATGGAAACGCTGGAACTGGCTCTCTCGGGCAATGCCGAAAAAGGCGATG
TCGTGGCAACGGCCCGGATCGCTGGCATCATGGCCGCGAAAAAGACGCATGAGCTGATCCCGCTCTGTCATCCGCTGCTC
CTGACCAAGGTTGGCGTCGATCTTGAACCCGATCCTTCGCTGCCCGGTTTTCGCGTCCAGGCCCTTGCCAAGGTGAAGGG
TCAGACTGGCGTCGAAATGGAAGCTTTGACCGCCGTCTCCGTGGCCTGCCTGACGCTTTATGACATGCTGAAGGCCGTTG
ACCGTTTCATGCGCATTGAAGGAATAGGCCTCCTGGAAAAACAGGGAGGCAAATCAGGTTCCTGGAAACGAGAAAAAGAA
TGA

Upstream 100 bases:

>100_bases
GAGCAAGATGTGACGGCGGCGACACGCCGGCTGCTCGATCTGCCGCCGGAGGCCGTGACGGGCCCGGTCCATGCCGTTTT
GGAGTCATGAGGGGCGCTTC

Downstream 100 bases:

>100_bases
ACGCGGTTGCCCCGCACAAAAATGCAGGTCCTGTTAAAACGGACCAACCGAAACCGGCCCTGTCCGTCGCTGAGGCGCGC
CGGACGATTTTGACGAGCGT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSSLTHLTSHGEAVMVDVSDKAETERVAIAEARVVMRMETLELALSGNAEKGDVVATARIAGIMAAKKTHELIPLCHPLL
LTKVGVDLEPDPSLPGFRVQALAKVKGQTGVEMEALTAVSVACLTLYDMLKAVDRFMRIEGIGLLEKQGGKSGSWKREKE

Sequences:

>Translated_160_residues
MSSLTHLTSHGEAVMVDVSDKAETERVAIAEARVVMRMETLELALSGNAEKGDVVATARIAGIMAAKKTHELIPLCHPLL
LTKVGVDLEPDPSLPGFRVQALAKVKGQTGVEMEALTAVSVACLTLYDMLKAVDRFMRIEGIGLLEKQGGKSGSWKREKE
>Mature_159_residues
SSLTHLTSHGEAVMVDVSDKAETERVAIAEARVVMRMETLELALSGNAEKGDVVATARIAGIMAAKKTHELIPLCHPLLL
TKVGVDLEPDPSLPGFRVQALAKVKGQTGVEMEALTAVSVACLTLYDMLKAVDRFMRIEGIGLLEKQGGKSGSWKREKE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=59.375, Blast_Score=177, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI32566331, Length=156, Percent_Identity=41.025641025641, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=47.5, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=48.9655172413793, Blast_Score=120, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_BEII9 (B2IKL8)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832546.1
- GeneID:   6199336
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1417
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   CLSK2405490
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17211; Mature: 17080

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLTHLTSHGEAVMVDVSDKAETERVAIAEARVVMRMETLELALSGNAEKGDVVATARI
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEHHHH
AGIMAAKKTHELIPLCHPLLLTKVGVDLEPDPSLPGFRVQALAKVKGQTGVEMEALTAVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
VACLTLYDMLKAVDRFMRIEGIGLLEKQGGKSGSWKREKE
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SSLTHLTSHGEAVMVDVSDKAETERVAIAEARVVMRMETLELALSGNAEKGDVVATARI
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEHHHH
AGIMAAKKTHELIPLCHPLLLTKVGVDLEPDPSLPGFRVQALAKVKGQTGVEMEALTAVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
VACLTLYDMLKAVDRFMRIEGIGLLEKQGGKSGSWKREKE
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA