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The map label for this gene is yajO [H]

Identifier: 182678259

GI number: 182678259

Start: 1482640

End: 1483587

Strand: Direct

Name: yajO [H]

Synonym: Bind_1275

Alternate gene names: 182678259

Gene position: 1482640-1483587 (Clockwise)

Preceding gene: 182678258

Following gene: 182678261

Centisome position: 35.55

GC content: 56.96

Gene sequence:

>948_bases
GTGAAATACCGTCAGCTCGGCGACAGCGATCTTCAGATTTCGACGATCTCCCTCGGGTCCTGGCTTACAACTGCCGGAGG
CATTGAAAAGGCTCAGGCTATTGCCTGTGTCCATAAGGCTTTGGATGTCGGTATCAATTTTATCGATACCGCGAATGTGT
ACGGGCGAGGCACTGCGGAAAGTGTTCTCGGCGAGGCCCTGAACGGGATCAGCCGCTCCTCTTATATTCTGGCGACCAAG
GTTTTTGGCGCGATGAGCGACACAGACAAAGGTCTCTCGCGCGAACAGATCGTCAAGCAGCTCGATGCCTCGCTGCGCCG
CTTGAAAACCGATTATGTCGATCTTTATCAATGCCATCGCTACGACGCGGATACACCGCTTGAGGAAACGATGGAGGCCC
TGACAGAGGAAGTCAAAAAGGGCAAGGTCCGCTATATCGGCTTCAGCGAATGGCCGCAGGACAAGATCGTGGAAGCATGC
GAAATGCTCGATATGGCGCCATTCGTATCGAGCCAGCCGCAATATTCCCTGCTCTGGCCCTATCCGCAGGCGGAGCTTTT
CGATCTTTGCGCCGATTACGGCATTACCCAGATCGTCTGGTCGCCGTTGGCGCAAGGCATTTTGACCGGAAAATATAAGC
CGAACCAAAATCCCCCTGGCTCCTCGCGTGTGGGGAACGAATCCATGGGGTCCATGGTGCCGAAACGCTGGCTTGAGGCG
CCGGTGCTTGAAGCCGTGCAAAAACTTCAGCCGCTTGCCGACGAGGCGGGGCTCACTCTGGCTCAATTCTCTCTTGCCTG
GGTGCTGCGCAAGGCCAATGTCTCCTCGGCGATCATCGGCGCCAGCCGCCCCGAGCAGGTTGTCGAAAATGCGGCTGCCG
CGGATGCTCAGGTCACGCAGGAACTCTTTTTCCGGGCCGAGGAAATTCTGGAGCCGGTCCGGCAGTAA

Upstream 100 bases:

>100_bases
CCATGGCCCAGCTTCTGCTTGGAAATGAGCGAAGGCATGAGGACTAGCAAGGCCCGTGACCGATTTGCGCGGCCTTGCGT
AAAGTATGAGGGATTTAGTC

Downstream 100 bases:

>100_bases
CCGAGCCTGAATCGGTGTCTTGCGTTCCTTCAGAGAGTGCTCATCCCGCCGTCGATGATCCATTCACTGCCCACGGCAAA
GGCGCCAGCATCTGAGGCGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKYRQLGDSDLQISTISLGSWLTTAGGIEKAQAIACVHKALDVGINFIDTANVYGRGTAESVLGEALNGISRSSYILATK
VFGAMSDTDKGLSREQIVKQLDASLRRLKTDYVDLYQCHRYDADTPLEETMEALTEEVKKGKVRYIGFSEWPQDKIVEAC
EMLDMAPFVSSQPQYSLLWPYPQAELFDLCADYGITQIVWSPLAQGILTGKYKPNQNPPGSSRVGNESMGSMVPKRWLEA
PVLEAVQKLQPLADEAGLTLAQFSLAWVLRKANVSSAIIGASRPEQVVENAAAADAQVTQELFFRAEEILEPVRQ

Sequences:

>Translated_315_residues
MKYRQLGDSDLQISTISLGSWLTTAGGIEKAQAIACVHKALDVGINFIDTANVYGRGTAESVLGEALNGISRSSYILATK
VFGAMSDTDKGLSREQIVKQLDASLRRLKTDYVDLYQCHRYDADTPLEETMEALTEEVKKGKVRYIGFSEWPQDKIVEAC
EMLDMAPFVSSQPQYSLLWPYPQAELFDLCADYGITQIVWSPLAQGILTGKYKPNQNPPGSSRVGNESMGSMVPKRWLEA
PVLEAVQKLQPLADEAGLTLAQFSLAWVLRKANVSSAIIGASRPEQVVENAAAADAQVTQELFFRAEEILEPVRQ
>Mature_315_residues
MKYRQLGDSDLQISTISLGSWLTTAGGIEKAQAIACVHKALDVGINFIDTANVYGRGTAESVLGEALNGISRSSYILATK
VFGAMSDTDKGLSREQIVKQLDASLRRLKTDYVDLYQCHRYDADTPLEETMEALTEEVKKGKVRYIGFSEWPQDKIVEAC
EMLDMAPFVSSQPQYSLLWPYPQAELFDLCADYGITQIVWSPLAQGILTGKYKPNQNPPGSSRVGNESMGSMVPKRWLEA
PVLEAVQKLQPLADEAGLTLAQFSLAWVLRKANVSSAIIGASRPEQVVENAAAADAQVTQELFFRAEEILEPVRQ

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=37.012987012987, Blast_Score=194, Evalue=8e-50,
Organism=Homo sapiens, GI27436969, Length=308, Percent_Identity=37.012987012987, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=36.6883116883117, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI4504825, Length=306, Percent_Identity=36.9281045751634, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=36.3636363636364, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI27436971, Length=308, Percent_Identity=35.7142857142857, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI41152114, Length=275, Percent_Identity=28.3636363636364, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI223718702, Length=277, Percent_Identity=27.4368231046931, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=28.3088235294118, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=37.1517027863777, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=36.4197530864198, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=32.4324324324324, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=29.9418604651163, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788081, Length=290, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786400, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=308, Percent_Identity=25.6493506493506, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17550248, Length=308, Percent_Identity=25.6493506493506, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=311, Percent_Identity=23.7942122186495, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=346, Percent_Identity=29.1907514450867, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=25.8566978193146, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=300, Percent_Identity=25, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=22.9965156794425, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24640980, Length=344, Percent_Identity=26.453488372093, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI45549126, Length=344, Percent_Identity=26.453488372093, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24646155, Length=159, Percent_Identity=41.5094339622642, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646159, Length=174, Percent_Identity=36.7816091954023, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644950, Length=320, Percent_Identity=24.6875, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34685; Mature: 34685

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRQLGDSDLQISTISLGSWLTTAGGIEKAQAIACVHKALDVGINFIDTANVYGRGTAE
CCCCCCCCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHH
SVLGEALNGISRSSYILATKVFGAMSDTDKGLSREQIVKQLDASLRRLKTDYVDLYQCHR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YDADTPLEETMEALTEEVKKGKVRYIGFSEWPQDKIVEACEMLDMAPFVSSQPQYSLLWP
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
YPQAELFDLCADYGITQIVWSPLAQGILTGKYKPNQNPPGSSRVGNESMGSMVPKRWLEA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PVLEAVQKLQPLADEAGLTLAQFSLAWVLRKANVSSAIIGASRPEQVVENAAAADAQVTQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
ELFFRAEEILEPVRQ
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYRQLGDSDLQISTISLGSWLTTAGGIEKAQAIACVHKALDVGINFIDTANVYGRGTAE
CCCCCCCCCCCEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHH
SVLGEALNGISRSSYILATKVFGAMSDTDKGLSREQIVKQLDASLRRLKTDYVDLYQCHR
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YDADTPLEETMEALTEEVKKGKVRYIGFSEWPQDKIVEACEMLDMAPFVSSQPQYSLLWP
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
YPQAELFDLCADYGITQIVWSPLAQGILTGKYKPNQNPPGSSRVGNESMGSMVPKRWLEA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PVLEAVQKLQPLADEAGLTLAQFSLAWVLRKANVSSAIIGASRPEQVVENAAAADAQVTQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
ELFFRAEEILEPVRQ
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]