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The map label for this gene is asd [H]

Identifier: 182678171

GI number: 182678171

Start: 1376088

End: 1377122

Strand: Direct

Name: asd [H]

Synonym: Bind_1186

Alternate gene names: 182678171

Gene position: 1376088-1377122 (Clockwise)

Preceding gene: 182678168

Following gene: 182678173

Centisome position: 33.0

GC content: 55.75

Gene sequence:

>1035_bases
ATGGGGTTCAAGGTTGCTGTCGTCGGCGCTACCGGTAATGTCGGGCGTGAAATGCTCGATATTCTCGCGGAGCGTCAGTT
TCCGGCCGATGAAGTCGTTGCACTGGCTTCCTCTCGTTCGATGGGAACGGAAGTCTCGTTCGGCGACAAAACCCTGAAAT
GTAAAACCCTGGACAATTACGATTTTACCGGCACGGATATTTGCCTGATGTCCGCCGGTGGCGCCGTTTCCAAGGAATGG
TCGCCGAAAATTGGAGCCCAGGGGTGCATCGTCATCGATAATTCTTCCACCTGGCGCATGGACCCGGACGTTCCCTTGAT
CGTGCCGGAGGTCAATGCCGATGCGATTGGCGGGTTCACGAAAAAGAACATCATCGCCAATCCCAATTGCTCGACGGCGC
AATTGGTCGTTGCGCTGAAGCCCTTGCACGACAAGGCCAAAATCCTGCGCGTCGTCGTCTCGACCTATCAATCCGTCTCT
GGCGGCGGCAAAGAGGCCATGGACGAGCTTTTTGCTCAGACACGGGCGATTTTTGTCTCGGATCCGGTGGAGAGCAAGAA
ATTCCCCAAAAGAATCGCTTTCAATGTGATTCCGGAAATCGACGTCTTCATGGAGGACGGCTATACGAAGGAAGAATGGA
AGATGGTGGTCGAGACGAAGAAAATTCTCGATCCGAAAATCAAGGTGACGGCCACTTGTGTCCGCGTGCCGGTGTTCATC
GGCCATTCCGAGTCCGTGAATGTCGAATTCGAGCATCCGATCAGCGCCGACGAGGCCCGCGATATTTTGCGCGAGGCGCC
GGGTTGTCTTGTCATCGATAAGAGGGAAAAAGGTGGCTACATAACGCCGCATGAGGCGGCGGGCGAGGATGCCACCTATA
TTTCCCGCATCCGGGAAGATCCGACGGTCGAAAACGGGCTCGTCTTCTGGTGCGTTTCGGACAATCTGCGCAAGGGTGCC
GCCTTGAATGCCGTGCAGATCGCCGAGGTCCTGATCAACCGCAAGCTGATCGAGCCGAAACGTAAGGCGGCGTGA

Upstream 100 bases:

>100_bases
TCGCTTATGCCGTTGAAAAAGCGAAAATTGGAGAGCGGAACCGAGCGTCGCTGTTGCGACACTTAAATATTAGCGATCGC
TTTGAGCGACGGAGAGAAGA

Downstream 100 bases:

>100_bases
GGGAAAGAGACAGCGTAACGATTTCGCTGGCTTTCAGTAGATAAACCCAATCATCAAAGGCGCTCTTTCTTCGAGAAAGG
GCGCCTCGCTTTTATCGATG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGFKVAVVGATGNVGREMLDILAERQFPADEVVALASSRSMGTEVSFGDKTLKCKTLDNYDFTGTDICLMSAGGAVSKEW
SPKIGAQGCIVIDNSSTWRMDPDVPLIVPEVNADAIGGFTKKNIIANPNCSTAQLVVALKPLHDKAKILRVVVSTYQSVS
GGGKEAMDELFAQTRAIFVSDPVESKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMVVETKKILDPKIKVTATCVRVPVFI
GHSESVNVEFEHPISADEARDILREAPGCLVIDKREKGGYITPHEAAGEDATYISRIREDPTVENGLVFWCVSDNLRKGA
ALNAVQIAEVLINRKLIEPKRKAA

Sequences:

>Translated_344_residues
MGFKVAVVGATGNVGREMLDILAERQFPADEVVALASSRSMGTEVSFGDKTLKCKTLDNYDFTGTDICLMSAGGAVSKEW
SPKIGAQGCIVIDNSSTWRMDPDVPLIVPEVNADAIGGFTKKNIIANPNCSTAQLVVALKPLHDKAKILRVVVSTYQSVS
GGGKEAMDELFAQTRAIFVSDPVESKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMVVETKKILDPKIKVTATCVRVPVFI
GHSESVNVEFEHPISADEARDILREAPGCLVIDKREKGGYITPHEAAGEDATYISRIREDPTVENGLVFWCVSDNLRKGA
ALNAVQIAEVLINRKLIEPKRKAA
>Mature_343_residues
GFKVAVVGATGNVGREMLDILAERQFPADEVVALASSRSMGTEVSFGDKTLKCKTLDNYDFTGTDICLMSAGGAVSKEWS
PKIGAQGCIVIDNSSTWRMDPDVPLIVPEVNADAIGGFTKKNIIANPNCSTAQLVVALKPLHDKAKILRVVVSTYQSVSG
GGKEAMDELFAQTRAIFVSDPVESKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMVVETKKILDPKIKVTATCVRVPVFIG
HSESVNVEFEHPISADEARDILREAPGCLVIDKREKGGYITPHEAAGEDATYISRIREDPTVENGLVFWCVSDNLRKGAA
LNAVQIAEVLINRKLIEPKRKAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=36.7952522255193, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789841, Length=359, Percent_Identity=28.4122562674095, Blast_Score=101, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6320362, Length=401, Percent_Identity=31.6708229426434, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37544; Mature: 37412

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKVAVVGATGNVGREMLDILAERQFPADEVVALASSRSMGTEVSFGDKTLKCKTLDNY
CCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DFTGTDICLMSAGGAVSKEWSPKIGAQGCIVIDNSSTWRMDPDVPLIVPEVNADAIGGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHCCCCC
KKNIIANPNCSTAQLVVALKPLHDKAKILRVVVSTYQSVSGGGKEAMDELFAQTRAIFVS
CCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEE
DPVESKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMVVETKKILDPKIKVTATCVRVPVFI
CCCCCHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNVEFEHPISADEARDILREAPGCLVIDKREKGGYITPHEAAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
PTVENGLVFWCVSDNLRKGAALNAVQIAEVLINRKLIEPKRKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure 
GFKVAVVGATGNVGREMLDILAERQFPADEVVALASSRSMGTEVSFGDKTLKCKTLDNY
CEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DFTGTDICLMSAGGAVSKEWSPKIGAQGCIVIDNSSTWRMDPDVPLIVPEVNADAIGGFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHCCCCC
KKNIIANPNCSTAQLVVALKPLHDKAKILRVVVSTYQSVSGGGKEAMDELFAQTRAIFVS
CCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEE
DPVESKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMVVETKKILDPKIKVTATCVRVPVFI
CCCCCHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSESVNVEFEHPISADEARDILREAPGCLVIDKREKGGYITPHEAAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
PTVENGLVFWCVSDNLRKGAALNAVQIAEVLINRKLIEPKRKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]