Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 182677772

GI number: 182677772

Start: 872727

End: 873374

Strand: Direct

Name: yggV [C]

Synonym: Bind_0779

Alternate gene names: 182677772

Gene position: 872727-873374 (Clockwise)

Preceding gene: 182677771

Following gene: 182677773

Centisome position: 20.93

GC content: 62.35

Gene sequence:

>648_bases
ATGCCTTTATCCCCTTCCGGTGCCGACCGATTGGTGATCGCCACGCATAATGCCGGCAAGCTGCGGGAAATGCGCGAATT
GCTCGCGCCCTATCGCATCACGGCTGTCTCGGCGGGCGAATTGAGGCTGCCTGAGCCGGAGGAAACCGGCGCAACTTTTA
TCGCCAATGCCGAGATCAAGGCGAAAGCCGCCGCCGAGCGTTCGGGCCTTCCGGCGCTGGCCGATGATTCCGGCCTCTGT
GTCGAGGGACTTGGCGGCGCGCCGGGCATTTATTCCGCGCGCTGGGCGGGCGAGGGCAAGGATTTCGCTGCCGCCATGAG
CCGTATCGCAATGGAGCTCGAAAAGGCCAAGGTGCCACCTCCGCATCGGGCCTATTTCGTCTCCGCGCTCGCTCTGGCTC
TGCCGGATGGCACGATCTCCACTTTCGAGGGCAAGGTTTTCGGAATTTTGGTCTTTCCGCCTCGCGGCACGCGCGGTTTT
GGCTACGATCCGATTTTCTTACCGGATGGCTATGAAAGAACCTTCGGGGAAATGGAGGCAGAGGAAAAGCACGGTCTGCC
CGCCGATGGCTCGCAGGCCCTGTCGCATCGGGCGCGCGCCTTTCAGCTTTTTGCCCGCGCCTGTTTGACGCAAGGCCCCC
CTGATTGA

Upstream 100 bases:

>100_bases
GCCGTCTTCAGCGAGGACGAGTTGAGCGTCCTTTTGGCTTTGGCCAAGGGCGGGATCGCCCAATTGGTGAATATCCAGAA
GCTCGCGATCGGCTGACCCC

Downstream 100 bases:

>100_bases
TTTTAAAGCGTCAATCTTCTATATTGCACTGCAATATCACTGACGATGAAGATCAGGTTCAGGGGGGCGTTTCATTCCTT
TCCGTGAAATCTTCTCGATT

Product: Ham1 family protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPLSPSGADRLVIATHNAGKLREMRELLAPYRITAVSAGELRLPEPEETGATFIANAEIKAKAAAERSGLPALADDSGLC
VEGLGGAPGIYSARWAGEGKDFAAAMSRIAMELEKAKVPPPHRAYFVSALALALPDGTISTFEGKVFGILVFPPRGTRGF
GYDPIFLPDGYERTFGEMEAEEKHGLPADGSQALSHRARAFQLFARACLTQGPPD

Sequences:

>Translated_215_residues
MPLSPSGADRLVIATHNAGKLREMRELLAPYRITAVSAGELRLPEPEETGATFIANAEIKAKAAAERSGLPALADDSGLC
VEGLGGAPGIYSARWAGEGKDFAAAMSRIAMELEKAKVPPPHRAYFVSALALALPDGTISTFEGKVFGILVFPPRGTRGF
GYDPIFLPDGYERTFGEMEAEEKHGLPADGSQALSHRARAFQLFARACLTQGPPD
>Mature_214_residues
PLSPSGADRLVIATHNAGKLREMRELLAPYRITAVSAGELRLPEPEETGATFIANAEIKAKAAAERSGLPALADDSGLCV
EGLGGAPGIYSARWAGEGKDFAAAMSRIAMELEKAKVPPPHRAYFVSALALALPDGTISTFEGKVFGILVFPPRGTRGFG
YDPIFLPDGYERTFGEMEAEEKHGLPADGSQALSHRARAFQLFARACLTQGPPD

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=198, Percent_Identity=32.3232323232323, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31657144, Length=144, Percent_Identity=34.7222222222222, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1789324, Length=202, Percent_Identity=41.0891089108911, Blast_Score=127, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=31.6326530612245, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322529, Length=203, Percent_Identity=29.5566502463054, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22824; Mature: 22693

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSPSGADRLVIATHNAGKLREMRELLAPYRITAVSAGELRLPEPEETGATFIANAEIK
CCCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEECCCCH
AKAAAERSGLPALADDSGLCVEGLGGAPGIYSARWAGEGKDFAAAMSRIAMELEKAKVPP
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
PHRAYFVSALALALPDGTISTFEGKVFGILVFPPRGTRGFGYDPIFLPDGYERTFGEMEA
CHHHHHHHHHHHHCCCCCCEEECCEEEEEEEECCCCCCCCCCCCEECCCCHHHHHHHCCH
EEKHGLPADGSQALSHRARAFQLFARACLTQGPPD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLSPSGADRLVIATHNAGKLREMRELLAPYRITAVSAGELRLPEPEETGATFIANAEIK
CCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEECCCCH
AKAAAERSGLPALADDSGLCVEGLGGAPGIYSARWAGEGKDFAAAMSRIAMELEKAKVPP
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
PHRAYFVSALALALPDGTISTFEGKVFGILVFPPRGTRGFGYDPIFLPDGYERTFGEMEA
CHHHHHHHHHHHHCCCCCCEEECCEEEEEEEECCCCCCCCCCCCEECCCCHHHHHHHCCH
EEKHGLPADGSQALSHRARAFQLFARACLTQGPPD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA