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The map label for this gene is yfhM [H]

Identifier: 182677695

GI number: 182677695

Start: 787405

End: 788298

Strand: Direct

Name: yfhM [H]

Synonym: Bind_0702

Alternate gene names: 182677695

Gene position: 787405-788298 (Clockwise)

Preceding gene: 182677694

Following gene: 182677696

Centisome position: 18.88

GC content: 58.05

Gene sequence:

>894_bases
ATGGATCTCCCTGTTACGACGCGTTTGATCGAGGCTAACGGTCTCATCTTCGAGATTGATGAATGCTTGCCCGCCAATGG
CGATACGCGAAAGCTCGCGCTTTGCCTGCATGGATTTCCGGAATCGAAATTTTCCTGGAAACACCAATTGCCGTTGCTTG
GGACGTTGGGCTACCGGGCCTGGGCGCCAAATTTGCGAGGCTATGGCGGAAGTTCACGCCCCAAAAGTGTCGGGGCCTAT
GGCCTTGATCATCTCGTCGCCGATGTGGAAGGTCTGATTGCGGCCTCCAAGGCCGAGGAGACCCTGTTGATCGGGCATGA
TTGGGGCGCAATCATTGCATGGCATTGCGCGATGCGGAAAATCCGCACCTTGAGCCGCCTCGTCATTATGAATGTGCCGC
ATCCAACGCGCTATATCGAGGAGATCGCCGTCAATCCAGCGCAGCGGCGCAAGAGCTGGTATGTCCTCTTCTTCCAATTG
CCGCGGATTCCTGAATTTGTGCTCACGCGCAACAAGGCGCGGGCCATATCCGGCATCATCTTGAAAATGGCGGTCGACAG
GAGCCGCTTTCCCGCTGAGGTTCTGGACCAGTATCGCGCCAATGCTCTGATCCCTGGCGCGATGACGGCGATGCTCAATT
ATTACCGCGCGGCTTTTCGCGCTGGCCGCAAGGCCATGGCTCCCTCACAAAACCGCGTCGAGGTTCCGACCCTGATCATC
TGGGGCGAGGAAGACGGGGCGCTGGAAAAATCCCTCGTTTTCGGCACCGAACGTTTCGTGTCGGACCTGACGGTGCGCTT
CCTCCCCGGTGTATCCCATTGGGTGCAGCAGGAAGCACCCGAAACGGTCAACGCAATCCTCCGCGCGTGGCTGACGCATG
TACCGAGCCTCTAA

Upstream 100 bases:

>100_bases
AGTGCCGGCACCCACGCCCTGGGCGTAATCGATTGAAGGGACTATGCAGCCAGCTGAGGCTGGCTGCATCCGATTTTGCT
TCCCGACTGGATGCAATGTC

Downstream 100 bases:

>100_bases
TAGGGGAGAGATCACATTGTGTCATGGGCTCCGGCGGGGGAAGATTTCCAGACTCGAGCGAAGCGGCAGCGATTTCTGGA
ATTCCATCATCGCTTGATAG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MDLPVTTRLIEANGLIFEIDECLPANGDTRKLALCLHGFPESKFSWKHQLPLLGTLGYRAWAPNLRGYGGSSRPKSVGAY
GLDHLVADVEGLIAASKAEETLLIGHDWGAIIAWHCAMRKIRTLSRLVIMNVPHPTRYIEEIAVNPAQRRKSWYVLFFQL
PRIPEFVLTRNKARAISGIILKMAVDRSRFPAEVLDQYRANALIPGAMTAMLNYYRAAFRAGRKAMAPSQNRVEVPTLII
WGEEDGALEKSLVFGTERFVSDLTVRFLPGVSHWVQQEAPETVNAILRAWLTHVPSL

Sequences:

>Translated_297_residues
MDLPVTTRLIEANGLIFEIDECLPANGDTRKLALCLHGFPESKFSWKHQLPLLGTLGYRAWAPNLRGYGGSSRPKSVGAY
GLDHLVADVEGLIAASKAEETLLIGHDWGAIIAWHCAMRKIRTLSRLVIMNVPHPTRYIEEIAVNPAQRRKSWYVLFFQL
PRIPEFVLTRNKARAISGIILKMAVDRSRFPAEVLDQYRANALIPGAMTAMLNYYRAAFRAGRKAMAPSQNRVEVPTLII
WGEEDGALEKSLVFGTERFVSDLTVRFLPGVSHWVQQEAPETVNAILRAWLTHVPSL
>Mature_297_residues
MDLPVTTRLIEANGLIFEIDECLPANGDTRKLALCLHGFPESKFSWKHQLPLLGTLGYRAWAPNLRGYGGSSRPKSVGAY
GLDHLVADVEGLIAASKAEETLLIGHDWGAIIAWHCAMRKIRTLSRLVIMNVPHPTRYIEEIAVNPAQRRKSWYVLFFQL
PRIPEFVLTRNKARAISGIILKMAVDRSRFPAEVLDQYRANALIPGAMTAMLNYYRAAFRAGRKAMAPSQNRVEVPTLII
WGEEDGALEKSLVFGTERFVSDLTVRFLPGVSHWVQQEAPETVNAILRAWLTHVPSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=287, Percent_Identity=33.1010452961672, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI218777840, Length=262, Percent_Identity=32.0610687022901, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI13376164, Length=262, Percent_Identity=32.0610687022901, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI27597073, Length=287, Percent_Identity=27.8745644599303, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562298, Length=272, Percent_Identity=36.0294117647059, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17554012, Length=270, Percent_Identity=31.4814814814815, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 33294; Mature: 33294

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPVTTRLIEANGLIFEIDECLPANGDTRKLALCLHGFPESKFSWKHQLPLLGTLGYRA
CCCCCCEEEEECCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHCCCHH
WAPNLRGYGGSSRPKSVGAYGLDHLVADVEGLIAASKAEETLLIGHDWGAIIAWHCAMRK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
IRTLSRLVIMNVPHPTRYIEEIAVNPAQRRKSWYVLFFQLPRIPEFVLTRNKARAISGII
HHHHHHHEEEECCCHHHHHHHHHCCHHHHCCCEEEEEEECCCCCHHHHCCCHHHHHHHHH
LKMAVDRSRFPAEVLDQYRANALIPGAMTAMLNYYRAAFRAGRKAMAPSQNRVEVPTLII
HHHHHCCCCCCHHHHHHHHCCEECCHHHHHHHHHHHHHHHCCCHHCCCCCCCEECCEEEE
WGEEDGALEKSLVFGTERFVSDLTVRFLPGVSHWVQQEAPETVNAILRAWLTHVPSL
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLPVTTRLIEANGLIFEIDECLPANGDTRKLALCLHGFPESKFSWKHQLPLLGTLGYRA
CCCCCCEEEEECCCCEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHCCCHH
WAPNLRGYGGSSRPKSVGAYGLDHLVADVEGLIAASKAEETLLIGHDWGAIIAWHCAMRK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
IRTLSRLVIMNVPHPTRYIEEIAVNPAQRRKSWYVLFFQLPRIPEFVLTRNKARAISGII
HHHHHHHEEEECCCHHHHHHHHHCCHHHHCCCEEEEEEECCCCCHHHHCCCHHHHHHHHH
LKMAVDRSRFPAEVLDQYRANALIPGAMTAMLNYYRAAFRAGRKAMAPSQNRVEVPTLII
HHHHHCCCCCCHHHHHHHHCCEECCHHHHHHHHHHHHHHHCCCHHCCCCCCCEECCEEEE
WGEEDGALEKSLVFGTERFVSDLTVRFLPGVSHWVQQEAPETVNAILRAWLTHVPSL
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]