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The map label for this gene is ruvA

Identifier: 182677007

GI number: 182677007

Start: 3668

End: 4285

Strand: Direct

Name: ruvA

Synonym: Bind_0005

Alternate gene names: 182677007

Gene position: 3668-4285 (Clockwise)

Preceding gene: 182677006

Following gene: 182677009

Centisome position: 0.09

GC content: 62.94

Gene sequence:

>618_bases
ATGATCGGCAAGCTGACCGGCCTCGTGGATAGCCAAGGGGAGGATCATGTGATCCTCGACGTGCAGGGCGTCGGCTACAT
CGTCTTTTGTTCGAGCCGGACTTTGCGGCTCCTGCCGAAGCCCGGCGCGTCGACCGCGCTCCTCATCGAGATGCAGGTGC
GCGAGGATGCGATCAGACTTTTTGGCTTTCCCTCGGAAGTCGAGCGCGACTGGTTCCGCCTGTTGCAATCGGTGCAAGGC
GTCGGTGCGAAGGTTGCGCTCGCTTTGCAGGGCCTGCTCAGTGCCACCGAGCTTGCGCAGGCGATTGCCCTTCAGGACAA
AGCCTCTCTTGGCCGTGCACCTGGAGTCGGCCCGAAACTCGCCGCCCGCCTCATCACGGAATTGAAGGATAAAATGCCGG
CGCTCGGGCCGGTCGATTCCCTGACAGCAAAGCTCACTATTGCCGAAGCAGAGGGTACGGCGCCTGTCGCCGCGCAAGAC
GCGATCACCGCTCTCGTTAATCTCGGCTATGGCCGGCCTCAAGCGGCGGCGGCTGTCGCGACATCGCTCGAAGCTTTGGG
AGAAACGGCGCCGCTCGCCGATTTGATTCGCCGCGGCCTGAAGGAATTGGCGCGGTAG

Upstream 100 bases:

>100_bases
GCGCTGATGCGGTCGATGCGCTCGCGGTCGCCATTACCCATGCGCAATTGCGGCGCAATCCCGCTGCTCTCAAAAGCCAA
GCTATGATTGGTCAGGGGCG

Downstream 100 bases:

>100_bases
CTTATCTACAGGCACTGGTGGCTGATGATGCGCTCACGCCTTGCCGTGATGCACGGCTTCGGCATTTGCATCGAGCGGCC
AGCGTGGTCTCGCGGCAAAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRLFGFPSEVERDWFRLLQSVQG
VGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKLAARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQD
AITALVNLGYGRPQAAAAVATSLEALGETAPLADLIRRGLKELAR

Sequences:

>Translated_205_residues
MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRLFGFPSEVERDWFRLLQSVQG
VGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKLAARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQD
AITALVNLGYGRPQAAAAVATSLEALGETAPLADLIRRGLKELAR
>Mature_205_residues
MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRLFGFPSEVERDWFRLLQSVQG
VGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKLAARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQD
AITALVNLGYGRPQAAAAVATSLEALGETAPLADLIRRGLKELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=206, Percent_Identity=35.4368932038835, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_BEII9 (B2IAW4)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831153.1
- GeneID:   6201467
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0005
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21429; Mature: 21429

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRL
CCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCEEEEEEEHHHHHHHHH
FGFPSEVERDWFRLLQSVQGVGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQDAITALVNLGYGRPQAAAAVA
HHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
TSLEALGETAPLADLIRRGLKELAR
HHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLTGLVDSQGEDHVILDVQGVGYIVFCSSRTLRLLPKPGASTALLIEMQVREDAIRL
CCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCEEEEEEEHHHHHHHHH
FGFPSEVERDWFRLLQSVQGVGAKVALALQGLLSATELAQAIALQDKASLGRAPGVGPKL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AARLITELKDKMPALGPVDSLTAKLTIAEAEGTAPVAAQDAITALVNLGYGRPQAAAAVA
HHHHHHHHHHHCCCCCCHHHHHEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
TSLEALGETAPLADLIRRGLKELAR
HHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA