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The map label for this gene is cheD4 [H]

Identifier: 17548129

GI number: 17548129

Start: 3688152

End: 3689699

Strand: Reverse

Name: cheD4 [H]

Synonym: RSc3412

Alternate gene names: 17548129

Gene position: 3689699-3688152 (Counterclockwise)

Preceding gene: 17548131

Following gene: 17548127

Centisome position: 99.28

GC content: 67.44

Gene sequence:

>1548_bases
TTGCGCAACTGGACCGTCAAGAGAAAGCTTGCCACCCTGGTCGCCTCGATCATCATTGCCTTCGTGTGCCTGACCGTCTT
CCTGCTCGGGCGCCAGGCCGCCGCGACGGCGGACATCCGGAGCCTGTACGACAAGGACTATCGCGCGGCGTCGATCATCG
GCCAGATCGACGGGCTGCTCACCCGCGTGGATATCAACATCCTGCGGATGATCGCCATCGGCGATCCGGCTTCCATCTCG
GGCTGGAAGGCCCAGAACACGGAGCGTTTCAACAAGGTCGACCAACTGCTGGTGGAGTTGGACGCATCGGCCGACCCGAG
CATGGCGGCATCGATCAAGACCCTGGGCGAGGCCTATGGCCGCATGCGCAAGGGCATGGAGCACCAGGTCGAGGCGGTCG
AGGCGGGTGATATCAAGCGCGGCGGCGAGATCAACAAGAACGAGGTCAAGGACAACGCCGACAAGACGTTCGGCACGCTG
GCCGAGCTCAAGAGCGCGCAGGACCTGATCGCCAAGAACAAGGTCCAGGCCCAGGAAGCGGCGGCGGCATTGGCCCGCGT
GGTCTCGATCACGGCGGCGGCGCTGATCGCGCTCGGCTCGCTGGGTCTCGGGCTGCTGATGCTGCGCGACCTGCTGCGCC
AGCTCGGCGGCGAGCCGTCGGTGGCGGCCCAGGCGGTCAGCGCCATGGCGCAGGGCGACCTTTCCCGCGTGATTGCCGTC
GACGCAGACGATAGGACGAGCCTGCTGGCCAAGCTCAAGGAGATGCAGGCGTCGCTGTCCGGCATCGTGGCCACCGTGCG
CAACAACGCCGAAAGCGTGGCCACGGCCAGCGCCCAGATCGCGCAGGGCAATCAGGACCTGAGCCATCGCACCGAGCAGC
AGGCCAGCGCGCTGCAGGAGACGTCGGCGACGATGGATGAGCTGGGCTCGACCGTGGGCAACAATGCCGAGAACGCGCGC
CAGGCCAATCAGCTCGCGTCGGGGGCCTCCAGCGTTGCCGCCGAGGGTGGCGAGGTGGTCAGCCAGGTGGTCGGCATGAT
GAAGGGGATCAACGATGGCTCCAAGAAGATCGCCGACATCATCGGCGTCATCGACGGCATTGCGTTCCAGACCAACATTC
TGGCGTTGAACGCCGCGGTGGAGGCCGCACGCGCGGGCGAGCAGGGCCGCGGGTTCGCGGTGGTCGCCGCCGAGGTGCGC
AGCCTGGCGCAGCGCAGTGCCGCGGCTGCCAAGGAAATCAAGGCGTTGATCACGAGCAGTGTCGAGCAGGTTGAACAGGG
CACCACGCTGGTCGACCGGGCCGGCGCGACGATGGAACAGATCGTGGGCGCGATCCAGCGCGTGTCCAACATCGTCGCCG
AGATCAGCTCGGCCAGCGCGGAGCAGAGCTCCGGCGTCTCGCAGGTCGGCCAGGCCGTCAGCCAGATGGACGAGGCCACG
CAGCAGAACGCCGCGCTGGTCGAGCAAAGCGCGGCGGCCGCGAGCAGCCTGCAAGGCCAGGCACAGCAGCTCGTGCAGGC
CGTCGCGGTGTTCAAGCTGGCGCGGTAG

Upstream 100 bases:

>100_bases
GTTACCCCTCAGAAGAGCCTTGCTCTTCACACCACGCGCCCGCACGCCCGAGCCGCTTCTCGAGGTTTGCCGGTGCAAGC
CATCGATTGGAGAATTGCCC

Downstream 100 bases:

>100_bases
TCCGCGCCGCAGGCAACAAGAAGAGCCGGCCAGCCGGCTCGCTTCCGGAAAACCGTCGGGCGGCCACGCCCGACGATGGG
GGATCGCCGTTGGTCCGGCC

Product: methyl-accepting chemotaxis I (serine chemoreceptor) transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MRNWTVKRKLATLVASIIIAFVCLTVFLLGRQAAATADIRSLYDKDYRAASIIGQIDGLLTRVDINILRMIAIGDPASIS
GWKAQNTERFNKVDQLLVELDASADPSMAASIKTLGEAYGRMRKGMEHQVEAVEAGDIKRGGEINKNEVKDNADKTFGTL
AELKSAQDLIAKNKVQAQEAAAALARVVSITAAALIALGSLGLGLLMLRDLLRQLGGEPSVAAQAVSAMAQGDLSRVIAV
DADDRTSLLAKLKEMQASLSGIVATVRNNAESVATASAQIAQGNQDLSHRTEQQASALQETSATMDELGSTVGNNAENAR
QANQLASGASSVAAEGGEVVSQVVGMMKGINDGSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVR
SLAQRSAAAAKEIKALITSSVEQVEQGTTLVDRAGATMEQIVGAIQRVSNIVAEISSASAEQSSGVSQVGQAVSQMDEAT
QQNAALVEQSAAAASSLQGQAQQLVQAVAVFKLAR

Sequences:

>Translated_515_residues
MRNWTVKRKLATLVASIIIAFVCLTVFLLGRQAAATADIRSLYDKDYRAASIIGQIDGLLTRVDINILRMIAIGDPASIS
GWKAQNTERFNKVDQLLVELDASADPSMAASIKTLGEAYGRMRKGMEHQVEAVEAGDIKRGGEINKNEVKDNADKTFGTL
AELKSAQDLIAKNKVQAQEAAAALARVVSITAAALIALGSLGLGLLMLRDLLRQLGGEPSVAAQAVSAMAQGDLSRVIAV
DADDRTSLLAKLKEMQASLSGIVATVRNNAESVATASAQIAQGNQDLSHRTEQQASALQETSATMDELGSTVGNNAENAR
QANQLASGASSVAAEGGEVVSQVVGMMKGINDGSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVR
SLAQRSAAAAKEIKALITSSVEQVEQGTTLVDRAGATMEQIVGAIQRVSNIVAEISSASAEQSSGVSQVGQAVSQMDEAT
QQNAALVEQSAAAASSLQGQAQQLVQAVAVFKLAR
>Mature_515_residues
MRNWTVKRKLATLVASIIIAFVCLTVFLLGRQAAATADIRSLYDKDYRAASIIGQIDGLLTRVDINILRMIAIGDPASIS
GWKAQNTERFNKVDQLLVELDASADPSMAASIKTLGEAYGRMRKGMEHQVEAVEAGDIKRGGEINKNEVKDNADKTFGTL
AELKSAQDLIAKNKVQAQEAAAALARVVSITAAALIALGSLGLGLLMLRDLLRQLGGEPSVAAQAVSAMAQGDLSRVIAV
DADDRTSLLAKLKEMQASLSGIVATVRNNAESVATASAQIAQGNQDLSHRTEQQASALQETSATMDELGSTVGNNAENAR
QANQLASGASSVAAEGGEVVSQVVGMMKGINDGSKKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVR
SLAQRSAAAAKEIKALITSSVEQVEQGTTLVDRAGATMEQIVGAIQRVSNIVAEISSASAEQSSGVSQVGQAVSQMDEAT
QQNAALVEQSAAAASSLQGQAQQLVQAVAVFKLAR

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=290, Percent_Identity=58.9655172413793, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1788194, Length=409, Percent_Identity=45.9657701711491, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI2367378, Length=290, Percent_Identity=59.6551724137931, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=50, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1789453, Length=254, Percent_Identity=43.7007874015748, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53530; Mature: 53530

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNWTVKRKLATLVASIIIAFVCLTVFLLGRQAAATADIRSLYDKDYRAASIIGQIDGLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TRVDINILRMIAIGDPASISGWKAQNTERFNKVDQLLVELDASADPSMAASIKTLGEAYG
HHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RMRKGMEHQVEAVEAGDIKRGGEINKNEVKDNADKTFGTLAELKSAQDLIAKNKVQAQEA
HHHHCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALARVVSITAAALIALGSLGLGLLMLRDLLRQLGGEPSVAAQAVSAMAQGDLSRVIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHEEEE
DADDRTSLLAKLKEMQASLSGIVATVRNNAESVATASAQIAQGNQDLSHRTEQQASALQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TSATMDELGSTVGNNAENARQANQLASGASSVAAEGGEVVSQVVGMMKGINDGSKKIADI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHH
IGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSAAAAKEIKALITSS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEQVEQGTTLVDRAGATMEQIVGAIQRVSNIVAEISSASAEQSSGVSQVGQAVSQMDEAT
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
QQNAALVEQSAAAASSLQGQAQQLVQAVAVFKLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNWTVKRKLATLVASIIIAFVCLTVFLLGRQAAATADIRSLYDKDYRAASIIGQIDGLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TRVDINILRMIAIGDPASISGWKAQNTERFNKVDQLLVELDASADPSMAASIKTLGEAYG
HHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RMRKGMEHQVEAVEAGDIKRGGEINKNEVKDNADKTFGTLAELKSAQDLIAKNKVQAQEA
HHHHCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALARVVSITAAALIALGSLGLGLLMLRDLLRQLGGEPSVAAQAVSAMAQGDLSRVIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHEEEE
DADDRTSLLAKLKEMQASLSGIVATVRNNAESVATASAQIAQGNQDLSHRTEQQASALQE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TSATMDELGSTVGNNAENARQANQLASGASSVAAEGGEVVSQVVGMMKGINDGSKKIADI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHH
IGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSAAAAKEIKALITSS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEQVEQGTTLVDRAGATMEQIVGAIQRVSNIVAEISSASAEQSSGVSQVGQAVSQMDEAT
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
QQNAALVEQSAAAASSLQGQAQQLVQAVAVFKLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]