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The map label for this gene is minD [H]

Identifier: 17548082

GI number: 17548082

Start: 3625030

End: 3625845

Strand: Direct

Name: minD [H]

Synonym: RSc3365

Alternate gene names: 17548082

Gene position: 3625030-3625845 (Clockwise)

Preceding gene: 17548081

Following gene: 17548083

Centisome position: 97.54

GC content: 63.85

Gene sequence:

>816_bases
ATGACCAAGATCATCGTAGTCACCTCCGGCAAGGGCGGTGTCGGCAAGACGACCACCAGCGCGGCCTTCTCCGCCGGCCT
CGCGCTGCGTGGCCACAAGACCGCCGTGATCGACTTCGACGTCGGCCTGCGCAACCTCGACCTCATCATGGGCTGCGAGC
GTCGCGTGGTGTACGACCTGATCAACGTGATTCACGGCGAGGCCAACCTGAACCAGGCGCTGATCAAGGACAAGAAGTGC
GAGAACCTGTTCATCCTGCCGGCCTCGCAGACGCGCGACAAGGATGCGCTCACGCGTGAAGGCGTCGAGAAGGTCATCAG
CGGCCTGACCGACATGGGCTTCGAATACATCGTCTGCGACTCGCCGGCCGGCATCGAATCCGGTGCGCTGATGGCGATGT
ATTTCGCCGATGAGGCCATCGTCGTGACCAACCCGGAAGTCTCGTCGGTGCGCGACTCCGACCGCATCCTGGGCATCCTG
TCGTCCAAGTCGCGCCGCGCCATCGAGGGCAAGGAGCCGATCCAGGAGCATCTGCTGCTCACGCGCTACAACCCCAAGCG
CGTGTCCGAGGGCGAGATGCTGTCGCTGACCGACGTGCAGGAGATCCTGCGCATCAAGCTGATCGGCGTGATTCCGGAAT
CGGAAGCCGTGCTGCAAGCGTCCAACCAGGGCATCCCGGCCATCCACCTGGACGGCACCGACGTGGCCGCCGCCTATGCC
GACGTGATCGACCGCTTCCTGGGCAAGGAAAAGCCGCTGCGCTACGTTGAGTACAGCAAGCCGGGCTTCCTGCAGCGCCT
GTTCGGCGGCAAATAA

Upstream 100 bases:

>100_bases
CAGATCCGGCTGTCGGAGAACACGCTGGTTCTCGAACCGTTGCGGATGAAATGACGCGCCCCGTGCGTGCCGAGCGACTT
AACTTTCAGATAGACGAACC

Downstream 100 bases:

>100_bases
GGAGACGCCATGTCGATCCTGTCTTTCCTGCTGGGCGAGAAGAAGAAGACCGCGAGCGTCGCCAAGGAACGCCTGCAGAT
CATCCTCGCCCACGAGCGGT

Product: septum site-determining protein MIND

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTKIIVVTSGKGGVGKTTTSAAFSAGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEANLNQALIKDKKC
ENLFILPASQTRDKDALTREGVEKVISGLTDMGFEYIVCDSPAGIESGALMAMYFADEAIVVTNPEVSSVRDSDRILGIL
SSKSRRAIEGKEPIQEHLLLTRYNPKRVSEGEMLSLTDVQEILRIKLIGVIPESEAVLQASNQGIPAIHLDGTDVAAAYA
DVIDRFLGKEKPLRYVEYSKPGFLQRLFGGK

Sequences:

>Translated_271_residues
MTKIIVVTSGKGGVGKTTTSAAFSAGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEANLNQALIKDKKC
ENLFILPASQTRDKDALTREGVEKVISGLTDMGFEYIVCDSPAGIESGALMAMYFADEAIVVTNPEVSSVRDSDRILGIL
SSKSRRAIEGKEPIQEHLLLTRYNPKRVSEGEMLSLTDVQEILRIKLIGVIPESEAVLQASNQGIPAIHLDGTDVAAAYA
DVIDRFLGKEKPLRYVEYSKPGFLQRLFGGK
>Mature_270_residues
TKIIVVTSGKGGVGKTTTSAAFSAGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIHGEANLNQALIKDKKCE
NLFILPASQTRDKDALTREGVEKVISGLTDMGFEYIVCDSPAGIESGALMAMYFADEAIVVTNPEVSSVRDSDRILGILS
SKSRRAIEGKEPIQEHLLLTRYNPKRVSEGEMLSLTDVQEILRIKLIGVIPESEAVLQASNQGIPAIHLDGTDVAAAYAD
VIDRFLGKEKPLRYVEYSKPGFLQRLFGGK

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=74.0740740740741, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29521; Mature: 29390

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIVVTSGKGGVGKTTTSAAFSAGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDL
CEEEEEEECCCCCCCCCCHHHHHHCCEEECCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
INVIHGEANLNQALIKDKKCENLFILPASQTRDKDALTREGVEKVISGLTDMGFEYIVCD
HHHHCCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
SPAGIESGALMAMYFADEAIVVTNPEVSSVRDSDRILGILSSKSRRAIEGKEPIQEHLLL
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCEEE
TRYNPKRVSEGEMLSLTDVQEILRIKLIGVIPESEAVLQASNQGIPAIHLDGTDVAAAYA
EECCCCCCCCCCEEEHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCEEEECCCHHHHHHH
DVIDRFLGKEKPLRYVEYSKPGFLQRLFGGK
HHHHHHHCCCCCCEEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
TKIIVVTSGKGGVGKTTTSAAFSAGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDL
EEEEEEECCCCCCCCCCHHHHHHCCEEECCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
INVIHGEANLNQALIKDKKCENLFILPASQTRDKDALTREGVEKVISGLTDMGFEYIVCD
HHHHCCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
SPAGIESGALMAMYFADEAIVVTNPEVSSVRDSDRILGILSSKSRRAIEGKEPIQEHLLL
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHCEEE
TRYNPKRVSEGEMLSLTDVQEILRIKLIGVIPESEAVLQASNQGIPAIHLDGTDVAAAYA
EECCCCCCCCCCEEEHHHHHHHHHEEEEEECCCCHHHHHHCCCCCCEEEECCCHHHHHHH
DVIDRFLGKEKPLRYVEYSKPGFLQRLFGGK
HHHHHHHCCCCCCEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]