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The map label for this gene is braD [H]

Identifier: 17548058

GI number: 17548058

Start: 3601419

End: 3602360

Strand: Reverse

Name: braD [H]

Synonym: RSc3341

Alternate gene names: 17548058

Gene position: 3602360-3601419 (Counterclockwise)

Preceding gene: 17548059

Following gene: 17548057

Centisome position: 96.93

GC content: 65.18

Gene sequence:

>942_bases
GTGTCGTCCGGCGCGTGCCGGGCGGCGCCGGCAACGGTCTCTTTTTCCCGATACGTGATGGAAATCTTCGGCGTTCCGCT
ACCGGCCATGCTCAGCCAGCTGTTGCTGGGCCTGGTCAACGGTTCCTTCTACGCGATGCTGAGCCTGGGCCTTGCGGTCA
TCTTCGGGCTGCTCAACGTCATCAATTTCGCGCACGGCGCGCTGTTCATGCTGGGCGCCGTGCTCACCTGGATGGGCCTG
TCGTATCTCGACCTGCCGTACTGGGTGATGCTGGTGGCCGCGCCGCTCGCGGTCGGCGTGGTGGGCGTGGTGATCGAACG
CACCATGCTGCGCTTCATCTACAAGCTCGACCACCTCTACGGCCTGCTGCTGACGCTGGGCGTGACGCTAGTCATCGAAG
GCGTGTTCCGTGCCGTCTACGGTGTGTCGGGCCTGCCGTATTCGACGCCCGAGCTGCTGTCCGGCGCCACCGATCTCGGC
TTCATGGTGCTGCCCAACTATCGGGCCTGGGTGGTGGTGGCGTCGCTGACGGTGTGCTTCGCCACCTGGTTCATGATCGA
GAAGACCAAGCTGGGTGCCTACCTGCGCGCTGGCACCGAGAACCCCAAGCTGGTCGAGGCCTTCGGCGTCAATGTGCCGC
TGATGGTCACGCTCACCTATGGCTTCGGCGTGGCGCTGGCGGCGTTCGCCGGCGTGCTGGCCGCGCCCGTGATCCAGATC
TCGCCGCTGATGGGGCAGAACATGATCATCACCGTGTTCGCGGTGGTGGTGATCGGCGGCATGGGGTCGATCCTCGGCTC
GATCGTCACCGGCCTGGGGCTGGGCGTGATCGAGGGGCTGACCAAGGTGGTCTATCCGCAGGCCTCGTCCACCGTGGTGT
TCGTGATCATGGCGCTGGTGTTGCTGGTGCGCCCGGCGGGCCTGTTCGGCAGAGAGAAATAA

Upstream 100 bases:

>100_bases
TACATGAAGATCGTGGCGACCATTCCGGGCGACCAGGCATTCACCACGCCGGCCGAGTCGAAGTGCCCGCTGCTCAAGAA
GTAAGGCGGCAAGCCATCCG

Downstream 100 bases:

>100_bases
GAGACAAGCGACGCGGCCAACATGAACCACTCGTCCTCCTTCAAGTTCATCCTGTACGGCCTGCTGCTGGCGGCGCTGAT
CGTCGCGCCGCTGGCGGGGG

Product: transmembrane ABC transporter protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSSGACRAAPATVSFSRYVMEIFGVPLPAMLSQLLLGLVNGSFYAMLSLGLAVIFGLLNVINFAHGALFMLGAVLTWMGL
SYLDLPYWVMLVAAPLAVGVVGVVIERTMLRFIYKLDHLYGLLLTLGVTLVIEGVFRAVYGVSGLPYSTPELLSGATDLG
FMVLPNYRAWVVVASLTVCFATWFMIEKTKLGAYLRAGTENPKLVEAFGVNVPLMVTLTYGFGVALAAFAGVLAAPVIQI
SPLMGQNMIITVFAVVVIGGMGSILGSIVTGLGLGVIEGLTKVVYPQASSTVVFVIMALVLLVRPAGLFGREK

Sequences:

>Translated_313_residues
MSSGACRAAPATVSFSRYVMEIFGVPLPAMLSQLLLGLVNGSFYAMLSLGLAVIFGLLNVINFAHGALFMLGAVLTWMGL
SYLDLPYWVMLVAAPLAVGVVGVVIERTMLRFIYKLDHLYGLLLTLGVTLVIEGVFRAVYGVSGLPYSTPELLSGATDLG
FMVLPNYRAWVVVASLTVCFATWFMIEKTKLGAYLRAGTENPKLVEAFGVNVPLMVTLTYGFGVALAAFAGVLAAPVIQI
SPLMGQNMIITVFAVVVIGGMGSILGSIVTGLGLGVIEGLTKVVYPQASSTVVFVIMALVLLVRPAGLFGREK
>Mature_312_residues
SSGACRAAPATVSFSRYVMEIFGVPLPAMLSQLLLGLVNGSFYAMLSLGLAVIFGLLNVINFAHGALFMLGAVLTWMGLS
YLDLPYWVMLVAAPLAVGVVGVVIERTMLRFIYKLDHLYGLLLTLGVTLVIEGVFRAVYGVSGLPYSTPELLSGATDLGF
MVLPNYRAWVVVASLTVCFATWFMIEKTKLGAYLRAGTENPKLVEAFGVNVPLMVTLTYGFGVALAAFAGVLAAPVIQIS
PLMGQNMIITVFAVVVIGGMGSILGSIVTGLGLGVIEGLTKVVYPQASSTVVFVIMALVLLVRPAGLFGREK

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=307, Percent_Identity=27.6872964169381, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 33141; Mature: 33010

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGACRAAPATVSFSRYVMEIFGVPLPAMLSQLLLGLVNGSFYAMLSLGLAVIFGLLNV
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
INFAHGALFMLGAVLTWMGLSYLDLPYWVMLVAAPLAVGVVGVVIERTMLRFIYKLDHLY
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLLTLGVTLVIEGVFRAVYGVSGLPYSTPELLSGATDLGFMVLPNYRAWVVVASLTVCF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCEEECCCCHHHHHHHHHHHHH
ATWFMIEKTKLGAYLRAGTENPKLVEAFGVNVPLMVTLTYGFGVALAAFAGVLAAPVIQI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
SPLMGQNMIITVFAVVVIGGMGSILGSIVTGLGLGVIEGLTKVVYPQASSTVVFVIMALV
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLVRPAGLFGREK
HHHCCCCCCCCCC
>Mature Secondary Structure 
SSGACRAAPATVSFSRYVMEIFGVPLPAMLSQLLLGLVNGSFYAMLSLGLAVIFGLLNV
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH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HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]