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The map label for this gene is putA [H]

Identifier: 17548018

GI number: 17548018

Start: 3558770

End: 3562747

Strand: Reverse

Name: putA [H]

Synonym: RSc3301

Alternate gene names: 17548018

Gene position: 3562747-3558770 (Counterclockwise)

Preceding gene: 17548019

Following gene: 17548017

Centisome position: 95.87

GC content: 69.86

Gene sequence:

>3978_bases
ATGGCTACGACCACCCTCGGGGTCAAGCTGGACGATGCTTCGCGCGAACGCCTCAAGCGCGCAGCCCAGTCCATTGACCG
CACACCGCACTGGCTGATCAAGCAGGCGATCTTCACCTATCTGGACCAAGTGGAGCGGGGGCAGCTGCCGAATGATGCGG
GCGGTCCGGCGGCGGATGGCCTCCCGTCCGCCGCCGCAGCCGTCGCGGACATGGCCGATGCCGATGGCACCGAGGCCGTG
GTGCAACCCTTCCTCGAATTCGCGCAGAGCGTGCAGCCGCAGTCGGTGCTGCGCGCCGCCATCACGGCCGCCTACCGCCG
GCCGGAAACCGAGGCGATTCCGATGCTGCTGGAGCAGGCCCGCCTGCCGGGCGCGCTGGCCTCCGAGGCCAAGCAGCTCG
CCCGCGACCTTGCCGGCAAGCTCCGTACGCAAAAGGTCGGCACCGGCCGCGAAGGTCTGGTGCAAGGTCTGATTCAAGAG
TTCTCCCTGTCGAGCCAGGAGGGCGTGGCGCTGATGTGCCTGGCCGAGGCACTGCTGCGCATTCCCGACAAGGCCACGCG
CGATGCGCTGATCCGCGACAAGATCAGCAGCGGCAACTGGCAGTCGCATCTGGGCCAGAGCCCGTCGTTGTTCGTCAACG
CCGCCACCTGGGGCCTGCTGCTGACGGGCAAGCTGGTGGCCACGCACAACGAGGCCGGACTGTCGAAGGCGCTCACGCGC
ATCATCGGCAAGCGCGGCGAGCCGCTGATCCGCAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCAC
CGGCGAGACCATTTCCGAAGCGCTGGCCAACGCCCGCAAGTACGAGGCCGAAGGCTTCCGCTACTCCTACGACATGCTCG
GCGAAGCCGCCATGACGGAAGAGGATGCCCAGCGCTACCTCGCGTCGTACGAGCAGGCCATCCGCGCGATCGGCCAGGCT
TCGGGCGGGCGCGGCATCTATGAGGGGCCGGGCATCTCGATCAAGCTGTCGGCGCTGCACCCGCGCTACAGCCGCGCCCA
GTACGACCGCGCCATCAATGAGCTGTATCCGCGCGTGAAGGGCCTGGCCATGCTGGCCCGCGAGTACGACATCGGCATCA
ACATCGATGCGGAAGAAGCCGACCGCCTGGAGCTGTCGCTCGATCTGCTCGAGCGCTTGTGCTTCGCGCCCGAGCTGGCC
GGCTGGAACGGCATCGGCTTCGTGGTGCAGGGCTACCAGAAGCGCTGCCCGTTCGTGCTCGACTACCTCATCGACCTGGC
GCGCCGCAGCAAGCACCGCCTGATGATTCGCCTGGTCAAGGGCGCCTACTGGGACAGCGAGATCAAGCGCGCCCAGGTCG
ACGGCCTGGAGGGCTATCCGGTCTATACGCGCAAGGTCTACACCGACGTGTCGTACCTGGCCTGCGCGCGCAAGCTGCTG
GCCGCGCCCGATGTCGTGTTTCCGCAGTTCGCCACGCACAACGCCCATACGCTGGCGGCCATCTATCACATGGCCGGGCA
GAACTATTACCCCGGCCAGTACGAATTCCAGTGCCTGCACGGCATGGGCGAGCCGCTGTACGAGCAGGTGGTCGGCAACA
AGCCGGGCAAGCTCAACCGGCCGTGCCGCATCTACGCGCCGGTCGGCACGCACGAGACGCTGCTGGCCTACCTGGTGCGC
CGCCTGCTGGAGAACGGCGCCAACACCTCGTTCGTCAACCGCATCGCGGACGAGTCGATTCCGCTGGACGAACTCGTCGC
CGATCCGGTGGCGGTGGTGGAGAACATGCACGCCGAGGAAGGCGCGCTCGGCCTGCCGCATCCGAAAATTCCGTTGCCGC
GCCATCTCTATGGTGATGTGCGTGCCAATTCGGCAGGGATCGACCTGGCGAACGAGCATCGGCTGGCGTCGTTGTCGTCT
GCGCTGCTGGCCGGTACCAGCTCGGTCTGGGCCGCTGAACCGACCATCGGCGATGCGCCATACACCGGTGGCACGCCGCA
ACCGGTGCGCAACCCGTCGGACCTGCGTGACGTGGTCGGCCACGTGACCGAAGCCACTGAAGCCGACGTCGATGCCGCGC
TGTCGGCCGCCGCCGCCGCCGCCCCGATCTGGCAAGCCACGCTGCCCGAAGCGCGTGCCGCGCTGCTCGATCGCGCCGCC
GACCTGATGGAAGGCGAGATGCAGCACCTGATGGGCCTGATCATCCGCGAGGCGGGCAAGACGCTGTCCAACGCGATCGC
CGAAGTGCGCGAGGCGGTGGACTTCCTGCGCTACTACGCGGCGCAGGTGCGTGGCGGGTTCTCCAACGACACGCACCGCC
CGCTGGGCCCGGTGGTCTGCATCAGCCCGTGGAACTTCCCGCTGGCGATCTTCACCGGCCAGGTGAGCGCGGCGCTGGCC
GCCGGCAACCCGGTGCTGGCCAAGCCCGCCGAGCAGACCCCGCTGATCGCCGCACAGGCCGTGCGCATCCTGCGCGAAGC
CGGCGTGCCGGCCGGCGCGGTGCAGCTGCTGCCGGGCCGCGGCGAGACCGTCGGGGCCGCACTGGTGAAGGATGCGCGCA
CCAAGGGCGTGATGTTCACCGGCTCGACCGAGGTGGCGCGCATCCTGCAGCGCACGCTGGCCGGCCGCCTGGATGCCAAC
GGTGCACCGATCCCGCTGATCGCCGAGACCGGCGGCCAGAACGCGATGATCGTCGATTCGTCGGCGCTGGCCGAGCAGGT
GGTGGCCGATGTGCTGTCGTCCGCCTTCGATTCCGCCGGGCAGCGCTGCTCGGCCCTGCGCGTGCTGTGCCTGCAGGACG
ACGTGGCCGACCGCGTGCTGGCGATGCTCAAGGGCGGCATGGCCGAGCTGGCGATGGGCAATCCCGATCGCCTGTCCACC
GACGTCGGCCCGGTGATCGACGCCGAGGCGCGCGACAACATCGTCGGCCATATCGAAGGGATGCGCGCCAAGGGCCGGCG
CGTGCACCAGGCGCCCGCGCCGGCTGCCTGCGCCCACGGCACCTTCGTGCCGCCGACGGTGATCGAACTCGACAGCCTGT
CGGACCTGACGCGCGAGATCTTCGGGCCGGTGCTGCACGTGGTCCGCTGGAAGCGCACAGCCGACAACGCCGGCCTCACC
CGGCTCATCGAGCAGATCAACGGCACGGGCTACGGCCTGACGCTGGGCATCCACACCCGCATCGACGAGACCATTGCGCA
CATCGTCGAGCGGGCGCGGGTGGGCAACCTGTACGTGAACCGCAATATCGTCGGCGCGGTGGTCGGCGTGCAGCCGTTCG
GCGGCGAGGGCCTGTCGGGCACCGGCCCGAAGGCGGGCGGCTCGCTGTATCTGCTGCGCCTGCTGTCGACCTGCCCGCAG
GACGCGATGCGCACGGCGCTGGAGTTGACCGCGGGCGCCGGCACCGACGTCGAGACCGAGGAGCGCCGCGCGCTGCTGGC
GCCGTTCGACGCGCTGCGTGACTGGGCGCGCCGGCAGTCGCCCGGGCTGGCCGCGCTGTGCGACCGCCTGGCGGCGGCCA
CGGCCACCGGCGCGGTTCTGACGCTGCCGGGCCCGACCGGCGAGCGCAACACCTATATGCTGCTGCCGCGCGACGCGGTG
CTGTGCGTGGCGGCCGATCCGGCCGACTGGCTGCGTCAGCTGGCGGCCGTGCTGGCGGTGGGCAGCGAGGCGGTCGTGCA
GGAAAACCCTGCCATCGCCGAGGTGCTGCGTACGCTGCCGTCGGCAGTACAATCGCGCGTCCGGACGGTGGCGTCGCTGG
AAGACGCGGCGTTCGACGCGGTGCTGCACCACGGCGATTCGGATCACCTGCGCGCCCTGTGCGAAGGGCTGGCGCGCCGT
GCCGGTCCGATCGTCGGCGTGCAGGGCTTGCCGCACGGCGGACAGGGGCTGGCGCTGGAGCGCCTGCTGATCGAGCGTTC
GCTGTCGGTCAACACGGCCGCGGCGGGTGGCAACGCCAGCCTGATGACCATCGGCTGA

Upstream 100 bases:

>100_bases
CAAGGGGTTCTACTAAGTTGCACCCCGCGAGCGGCCGGGCGTATGATCCGTTCGGTTTGCCGGCCACAAGCAGGCAAGGC
AGCTCAGCAAAGGAACCCTC

Downstream 100 bases:

>100_bases
CGGGGCGCACGAGCAGGATTCGCTGCGCCGCCTCCATGACAGGTGGGGGCGGGGCGCGAAGCGGGAGGAGGGCGGCGGCG
ATCCCGTCGCGCCATGGTTC

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1325; Mature: 1324

Protein sequence:

>1325_residues
MATTTLGVKLDDASRERLKRAAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDAGGPAADGLPSAAAAVADMADADGTEAV
VQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQE
FSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISSGNWQSHLGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTR
IIGKRGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQA
SGGRGIYEGPGISIKLSALHPRYSRAQYDRAINELYPRVKGLAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELA
GWNGIGFVVQGYQKRCPFVLDYLIDLARRSKHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLL
AAPDVVFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVR
RLLENGANTSFVNRIADESIPLDELVADPVAVVENMHAEEGALGLPHPKIPLPRHLYGDVRANSAGIDLANEHRLASLSS
ALLAGTSSVWAAEPTIGDAPYTGGTPQPVRNPSDLRDVVGHVTEATEADVDAALSAAAAAAPIWQATLPEARAALLDRAA
DLMEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALA
AGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDARTKGVMFTGSTEVARILQRTLAGRLDAN
GAPIPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLST
DVGPVIDAEARDNIVGHIEGMRAKGRRVHQAPAPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLT
RLIEQINGTGYGLTLGIHTRIDETIAHIVERARVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGSLYLLRLLSTCPQ
DAMRTALELTAGAGTDVETEERRALLAPFDALRDWARRQSPGLAALCDRLAAATATGAVLTLPGPTGERNTYMLLPRDAV
LCVAADPADWLRQLAAVLAVGSEAVVQENPAIAEVLRTLPSAVQSRVRTVASLEDAAFDAVLHHGDSDHLRALCEGLARR
AGPIVGVQGLPHGGQGLALERLLIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1325_residues
MATTTLGVKLDDASRERLKRAAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDAGGPAADGLPSAAAAVADMADADGTEAV
VQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQE
FSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISSGNWQSHLGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTR
IIGKRGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQA
SGGRGIYEGPGISIKLSALHPRYSRAQYDRAINELYPRVKGLAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELA
GWNGIGFVVQGYQKRCPFVLDYLIDLARRSKHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLL
AAPDVVFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVR
RLLENGANTSFVNRIADESIPLDELVADPVAVVENMHAEEGALGLPHPKIPLPRHLYGDVRANSAGIDLANEHRLASLSS
ALLAGTSSVWAAEPTIGDAPYTGGTPQPVRNPSDLRDVVGHVTEATEADVDAALSAAAAAAPIWQATLPEARAALLDRAA
DLMEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALA
AGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDARTKGVMFTGSTEVARILQRTLAGRLDAN
GAPIPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLST
DVGPVIDAEARDNIVGHIEGMRAKGRRVHQAPAPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLT
RLIEQINGTGYGLTLGIHTRIDETIAHIVERARVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGSLYLLRLLSTCPQ
DAMRTALELTAGAGTDVETEERRALLAPFDALRDWARRQSPGLAALCDRLAAATATGAVLTLPGPTGERNTYMLLPRDAV
LCVAADPADWLRQLAAVLAVGSEAVVQENPAIAEVLRTLPSAVQSRVRTVASLEDAAFDAVLHHGDSDHLRALCEGLARR
AGPIVGVQGLPHGGQGLALERLLIERSLSVNTAAAGGNASLMTIG
>Mature_1324_residues
ATTTLGVKLDDASRERLKRAAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDAGGPAADGLPSAAAAVADMADADGTEAVV
QPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQARLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEF
SLSSQEGVALMCLAEALLRIPDKATRDALIRDKISSGNWQSHLGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTRI
IGKRGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAEGFRYSYDMLGEAAMTEEDAQRYLASYEQAIRAIGQAS
GGRGIYEGPGISIKLSALHPRYSRAQYDRAINELYPRVKGLAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAG
WNGIGFVVQGYQKRCPFVLDYLIDLARRSKHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLA
APDVVFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNRPCRIYAPVGTHETLLAYLVRR
LLENGANTSFVNRIADESIPLDELVADPVAVVENMHAEEGALGLPHPKIPLPRHLYGDVRANSAGIDLANEHRLASLSSA
LLAGTSSVWAAEPTIGDAPYTGGTPQPVRNPSDLRDVVGHVTEATEADVDAALSAAAAAAPIWQATLPEARAALLDRAAD
LMEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVCISPWNFPLAIFTGQVSAALAA
GNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALVKDARTKGVMFTGSTEVARILQRTLAGRLDANG
APIPLIAETGGQNAMIVDSSALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLSTD
VGPVIDAEARDNIVGHIEGMRAKGRRVHQAPAPAACAHGTFVPPTVIELDSLSDLTREIFGPVLHVVRWKRTADNAGLTR
LIEQINGTGYGLTLGIHTRIDETIAHIVERARVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGSLYLLRLLSTCPQD
AMRTALELTAGAGTDVETEERRALLAPFDALRDWARRQSPGLAALCDRLAAATATGAVLTLPGPTGERNTYMLLPRDAVL
CVAADPADWLRQLAAVLAVGSEAVVQENPAIAEVLRTLPSAVQSRVRTVASLEDAAFDAVLHHGDSDHLRALCEGLARRA
GPIVGVQGLPHGGQGLALERLLIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=461, Percent_Identity=32.7548806941432, Blast_Score=198, Evalue=4e-50,
Organism=Homo sapiens, GI25777730, Length=457, Percent_Identity=31.9474835886214, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI25777732, Length=457, Percent_Identity=31.7286652078775, Blast_Score=190, Evalue=7e-48,
Organism=Homo sapiens, GI25777724, Length=515, Percent_Identity=28.9320388349515, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI153266822, Length=453, Percent_Identity=30.242825607064, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI25777736, Length=497, Percent_Identity=30.3822937625755, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI25777734, Length=497, Percent_Identity=30.3822937625755, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI238859541, Length=497, Percent_Identity=30.3822937625755, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI25777728, Length=409, Percent_Identity=29.8288508557457, Blast_Score=166, Evalue=2e-40,
Organism=Homo sapiens, GI12007648, Length=455, Percent_Identity=26.8131868131868, Blast_Score=155, Evalue=3e-37,
Organism=Homo sapiens, GI21614513, Length=425, Percent_Identity=28, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI115387104, Length=448, Percent_Identity=26.7857142857143, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI4507229, Length=498, Percent_Identity=28.1124497991968, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI238814322, Length=425, Percent_Identity=25.6470588235294, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI188035924, Length=469, Percent_Identity=28.3582089552239, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI310128093, Length=458, Percent_Identity=27.9475982532751, Blast_Score=136, Evalue=2e-31,
Organism=Homo sapiens, GI310128103, Length=458, Percent_Identity=27.9475982532751, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25777726, Length=515, Percent_Identity=25.8252427184466, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25777721, Length=511, Percent_Identity=27.3972602739726, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI11095441, Length=430, Percent_Identity=27.906976744186, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI25952152, Length=449, Percent_Identity=26.7260579064588, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI310128091, Length=400, Percent_Identity=28.75, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI206597441, Length=339, Percent_Identity=26.8436578171091, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI206597439, Length=339, Percent_Identity=26.8436578171091, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI22907049, Length=339, Percent_Identity=26.8436578171091, Blast_Score=100, Evalue=2e-20,
Organism=Homo sapiens, GI310128087, Length=269, Percent_Identity=30.1115241635688, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI71773324, Length=402, Percent_Identity=26.1194029850746, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI310128089, Length=338, Percent_Identity=27.2189349112426, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI4502043, Length=336, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI238814371, Length=336, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI4557303, Length=337, Percent_Identity=25.5192878338279, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI73466520, Length=337, Percent_Identity=25.5192878338279, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=27.639751552795, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI301500698, Length=443, Percent_Identity=22.7990970654628, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI73695881, Length=333, Percent_Identity=25.5255255255255, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI73695879, Length=333, Percent_Identity=25.5255255255255, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI310128099, Length=205, Percent_Identity=30.2439024390244, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128101, Length=205, Percent_Identity=30.2439024390244, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=27.8810408921933, Blast_Score=78, Evalue=7e-14,
Organism=Escherichia coli, GI1787250, Length=1333, Percent_Identity=70.7426856714179, Blast_Score=1855, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=463, Percent_Identity=30.6695464362851, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI1788042, Length=460, Percent_Identity=31.9565217391304, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1787558, Length=443, Percent_Identity=31.6027088036117, Blast_Score=161, Evalue=3e-40,
Organism=Escherichia coli, GI1787715, Length=466, Percent_Identity=31.9742489270386, Blast_Score=160, Evalue=5e-40,
Organism=Escherichia coli, GI87081896, Length=476, Percent_Identity=29.4117647058824, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=28.9130434782609, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI1786504, Length=469, Percent_Identity=28.1449893390192, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI87082295, Length=445, Percent_Identity=28.314606741573, Blast_Score=138, Evalue=3e-33,
Organism=Escherichia coli, GI87081926, Length=429, Percent_Identity=27.5058275058275, Blast_Score=123, Evalue=7e-29,
Organism=Escherichia coli, GI1787653, Length=358, Percent_Identity=22.6256983240223, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=465, Percent_Identity=31.6129032258064, Blast_Score=183, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=456, Percent_Identity=31.359649122807, Blast_Score=176, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=32.1951219512195, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534447, Length=498, Percent_Identity=31.5261044176707, Blast_Score=169, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=466, Percent_Identity=29.1845493562232, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=444, Percent_Identity=28.6036036036036, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=443, Percent_Identity=28.6681715575621, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=443, Percent_Identity=28.6681715575621, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115532534, Length=364, Percent_Identity=33.2417582417582, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=453, Percent_Identity=27.3730684326711, Blast_Score=139, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71986308, Length=428, Percent_Identity=28.2710280373832, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=452, Percent_Identity=27.6548672566372, Blast_Score=129, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=462, Percent_Identity=25.1082251082251, Blast_Score=126, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=409, Percent_Identity=27.6283618581907, Blast_Score=125, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=429, Percent_Identity=29.1375291375291, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=314, Percent_Identity=29.6178343949045, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=376, Percent_Identity=24.7340425531915, Blast_Score=94, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=376, Percent_Identity=24.7340425531915, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25146394, Length=376, Percent_Identity=24.7340425531915, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=334, Percent_Identity=26.3473053892216, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325196, Length=466, Percent_Identity=31.3304721030043, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320917, Length=455, Percent_Identity=31.6483516483516, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323821, Length=448, Percent_Identity=32.3660714285714, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=496, Percent_Identity=30.0403225806452, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=447, Percent_Identity=31.3199105145414, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=451, Percent_Identity=28.159645232816, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=460, Percent_Identity=27.1739130434783, Blast_Score=138, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6321828, Length=487, Percent_Identity=23.2032854209446, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=333, Percent_Identity=25.2252252252252, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129399, Length=455, Percent_Identity=31.2087912087912, Blast_Score=187, Evalue=5e-47,
Organism=Drosophila melanogaster, GI281362580, Length=451, Percent_Identity=28.3813747228381, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62472918, Length=451, Percent_Identity=28.3813747228381, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62472926, Length=451, Percent_Identity=28.3813747228381, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62472936, Length=451, Percent_Identity=28.3813747228381, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21356737, Length=451, Percent_Identity=28.3813747228381, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24650465, Length=451, Percent_Identity=30.1552106430155, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24668425, Length=532, Percent_Identity=28.1954887218045, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668417, Length=532, Percent_Identity=28.1954887218045, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24668413, Length=532, Percent_Identity=28.1954887218045, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24585660, Length=457, Percent_Identity=26.2582056892779, Blast_Score=155, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28571806, Length=482, Percent_Identity=27.5933609958506, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571798, Length=482, Percent_Identity=27.5933609958506, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571796, Length=482, Percent_Identity=27.5933609958506, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571794, Length=482, Percent_Identity=27.5933609958506, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571802, Length=482, Percent_Identity=27.5933609958506, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571800, Length=482, Percent_Identity=27.5933609958506, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574525, Length=490, Percent_Identity=27.1428571428571, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24666674, Length=472, Percent_Identity=28.1779661016949, Blast_Score=130, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24638876, Length=411, Percent_Identity=28.2238442822384, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24638878, Length=411, Percent_Identity=28.2238442822384, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360299, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281360297, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281360295, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24586250, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281360301, Length=337, Percent_Identity=28.1899109792285, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45552499, Length=341, Percent_Identity=26.3929618768328, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360303, Length=337, Percent_Identity=26.4094955489614, Blast_Score=95, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 141515; Mature: 141384

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDASRERLKRAAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDAGGPAADG
CCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPSAAAAVADMADADGTEAVVQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IPDKATRDALIRDKISSGNWQSHLGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTR
CCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECCCEEECCHHHHHHHHHH
IIGKRGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAEGFRYSYDMLGEAAMTE
HHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCH
EDAQRYLASYEQAIRAIGQASGGRGIYEGPGISIKLSALHPRYSRAQYDRAINELYPRVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
GLAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGWNGIGFVVQGYQKRCPFVL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHH
DYLIDLARRSKHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
AAPDVVFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCC
PCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADESIPLDELVADPVAVVENMHAEE
CEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHCCCCC
GALGLPHPKIPLPRHLYGDVRANSAGIDLANEHRLASLSSALLAGTSSVWAAEPTIGDAP
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCC
YTGGTPQPVRNPSDLRDVVGHVTEATEADVDAALSAAAAAAPIWQATLPEARAALLDRAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
DLMEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
ISPWNFPLAIFTGQVSAALAAGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGR
ECCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCC
GETVGAALVKDARTKGVMFTGSTEVARILQRTLAGRLDANGAPIPLIAETGGQNAMIVDS
CCHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECH
SALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
DVGPVIDAEARDNIVGHIEGMRAKGRRVHQAPAPAACAHGTFVPPTVIELDSLSDLTREI
CCCCCCCCHHHCCHHHHHCCHHHCCCCCCCCCCCCHHCCCCCCCCHHEEHHHHHHHHHHH
FGPVLHVVRWKRTADNAGLTRLIEQINGTGYGLTLGIHTRIDETIAHIVERARVGNLYVN
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEC
RNIVGAVVGVQPFGGEGLSGTGPKAGGSLYLLRLLSTCPQDAMRTALELTAGAGTDVETE
CCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
ERRALLAPFDALRDWARRQSPGLAALCDRLAAATATGAVLTLPGPTGERNTYMLLPRDAV
HHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEE
LCVAADPADWLRQLAAVLAVGSEAVVQENPAIAEVLRTLPSAVQSRVRTVASLEDAAFDA
EEEECCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLHHGDSDHLRALCEGLARRAGPIVGVQGLPHGGQGLALERLLIERSLSVNTAAAGGNAS
HHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCE
LMTIG
EEEEC
>Mature Secondary Structure 
ATTTLGVKLDDASRERLKRAAQSIDRTPHWLIKQAIFTYLDQVERGQLPNDAGGPAADG
CCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPSAAAAVADMADADGTEAVVQPFLEFAQSVQPQSVLRAAITAAYRRPETEAIPMLLEQA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLPGALASEAKQLARDLAGKLRTQKVGTGREGLVQGLIQEFSLSSQEGVALMCLAEALLR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
IPDKATRDALIRDKISSGNWQSHLGQSPSLFVNAATWGLLLTGKLVATHNEAGLSKALTR
CCCHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEHHHHHHHEECCCEEECCHHHHHHHHHH
IIGKRGEPLIRKGVDMAMRLMGEQFVTGETISEALANARKYEAEGFRYSYDMLGEAAMTE
HHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCH
EDAQRYLASYEQAIRAIGQASGGRGIYEGPGISIKLSALHPRYSRAQYDRAINELYPRVK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
GLAMLAREYDIGINIDAEEADRLELSLDLLERLCFAPELAGWNGIGFVVQGYQKRCPFVL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHCCCHHH
DYLIDLARRSKHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
AAPDVVFPQFATHNAHTLAAIYHMAGQNYYPGQYEFQCLHGMGEPLYEQVVGNKPGKLNR
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCC
PCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADESIPLDELVADPVAVVENMHAEE
CEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHCCCCC
GALGLPHPKIPLPRHLYGDVRANSAGIDLANEHRLASLSSALLAGTSSVWAAEPTIGDAP
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCC
YTGGTPQPVRNPSDLRDVVGHVTEATEADVDAALSAAAAAAPIWQATLPEARAALLDRAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
DLMEGEMQHLMGLIIREAGKTLSNAIAEVREAVDFLRYYAAQVRGGFSNDTHRPLGPVVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
ISPWNFPLAIFTGQVSAALAAGNPVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGR
ECCCCCCEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCC
GETVGAALVKDARTKGVMFTGSTEVARILQRTLAGRLDANGAPIPLIAETGGQNAMIVDS
CCHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEECH
SALAEQVVADVLSSAFDSAGQRCSALRVLCLQDDVADRVLAMLKGGMAELAMGNPDRLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
DVGPVIDAEARDNIVGHIEGMRAKGRRVHQAPAPAACAHGTFVPPTVIELDSLSDLTREI
CCCCCCCCHHHCCHHHHHCCHHHCCCCCCCCCCCCHHCCCCCCCCHHEEHHHHHHHHHHH
FGPVLHVVRWKRTADNAGLTRLIEQINGTGYGLTLGIHTRIDETIAHIVERARVGNLYVN
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEC
RNIVGAVVGVQPFGGEGLSGTGPKAGGSLYLLRLLSTCPQDAMRTALELTAGAGTDVETE
CCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
ERRALLAPFDALRDWARRQSPGLAALCDRLAAATATGAVLTLPGPTGERNTYMLLPRDAV
HHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCEE
LCVAADPADWLRQLAAVLAVGSEAVVQENPAIAEVLRTLPSAVQSRVRTVASLEDAAFDA
EEEECCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLHHGDSDHLRALCEGLARRAGPIVGVQGLPHGGQGLALERLLIERSLSVNTAAAGGNAS
HHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCE
LMTIG
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]