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The map label for this gene is marR [H]

Identifier: 17547858

GI number: 17547858

Start: 3389046

End: 3389525

Strand: Direct

Name: marR [H]

Synonym: RSc3139

Alternate gene names: 17547858

Gene position: 3389046-3389525 (Clockwise)

Preceding gene: 17547854

Following gene: 17547862

Centisome position: 91.19

GC content: 66.46

Gene sequence:

>480_bases
ATGAGCACCGAAGTCCAGACACCGCCCGAGGCAACCGACCAGGGCGCCTATCAACTCGACACCATGGATCGCGACACCAA
TGTCGGCCGGCTCGTCCACCGGGCCCGGCATGAGCTGGTGACGCACATCGACGCCGCCCTGGCGACGCTCGACCTGACCG
CCGCGCAGTGGACCGTGGTCGTCTACCTGGCCGAAGACCTGGCCAACACGCCGGCCGAGCTGTCGCGGCTGCTGAACTAC
GATCCGGGCGCGATGACGCGGCTGATCGACCGGCTGGAGAAGAAGAACATCGTCAAGCGCGCGCCCAGCGATGCGGACCG
GCGCTCGGTGGTGATCACGCTGACCGATCAGGGCCGCTCGCTGTATCCGGAGATCCGCCCGCTGATCGTCGACGTCCTGA
ACCATCTGCTGCGCGGGTTCACGCAGGCCGAGGTCAAGCAGTTGGAAAACCTCCTGCTGCGCGTGCTGCACAACGCATAG

Upstream 100 bases:

>100_bases
GCGACGATTAGCCTGCGTTCAGGATCCGGCGATGCGCTTACGGGAGTGCACGGCGGACCCACATAAGCCGGATCACCGGC
GCAGAACGGGGAGCACCACC

Downstream 100 bases:

>100_bases
CGCCGACGCCCGCGCATACCGGGTGCGTGCCTGGCCTCCGGCGACGCCGGGATGGGATCGGGCACGCACCGGACGGCCGG
CGGCCGCCGCCGCGCAGCGC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSTEVQTPPEATDQGAYQLDTMDRDTNVGRLVHRARHELVTHIDAALATLDLTAAQWTVVVYLAEDLANTPAELSRLLNY
DPGAMTRLIDRLEKKNIVKRAPSDADRRSVVITLTDQGRSLYPEIRPLIVDVLNHLLRGFTQAEVKQLENLLLRVLHNA

Sequences:

>Translated_159_residues
MSTEVQTPPEATDQGAYQLDTMDRDTNVGRLVHRARHELVTHIDAALATLDLTAAQWTVVVYLAEDLANTPAELSRLLNY
DPGAMTRLIDRLEKKNIVKRAPSDADRRSVVITLTDQGRSLYPEIRPLIVDVLNHLLRGFTQAEVKQLENLLLRVLHNA
>Mature_158_residues
STEVQTPPEATDQGAYQLDTMDRDTNVGRLVHRARHELVTHIDAALATLDLTAAQWTVVVYLAEDLANTPAELSRLLNYD
PGAMTRLIDRLEKKNIVKRAPSDADRRSVVITLTDQGRSLYPEIRPLIVDVLNHLLRGFTQAEVKQLENLLLRVLHNA

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=138, Percent_Identity=34.7826086956522, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17873; Mature: 17741

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEVQTPPEATDQGAYQLDTMDRDTNVGRLVHRARHELVTHIDAALATLDLTAAQWTVV
CCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLAEDLANTPAELSRLLNYDPGAMTRLIDRLEKKNIVKRAPSDADRRSVVITLTDQGRS
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
LYPEIRPLIVDVLNHLLRGFTQAEVKQLENLLLRVLHNA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STEVQTPPEATDQGAYQLDTMDRDTNVGRLVHRARHELVTHIDAALATLDLTAAQWTVV
CCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLAEDLANTPAELSRLLNYDPGAMTRLIDRLEKKNIVKRAPSDADRRSVVITLTDQGRS
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
LYPEIRPLIVDVLNHLLRGFTQAEVKQLENLLLRVLHNA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]