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The map label for this gene is acoR [H]

Identifier: 17547848

GI number: 17547848

Start: 3374673

End: 3376586

Strand: Direct

Name: acoR [H]

Synonym: RSc3129

Alternate gene names: 17547848

Gene position: 3374673-3376586 (Clockwise)

Preceding gene: 17547843

Following gene: 17547849

Centisome position: 90.8

GC content: 73.09

Gene sequence:

>1914_bases
ATGCAGGATCACCGCATGTCGCATCACACCGGCCAGGTGCTGACCCTCGCGCAGCACGACGCGCCCATCTCGGGTTCGCT
GTCCGGGCCGGCCGCCGATCCGTCCATCGCTCGCTCCTGGCTGCGCTGCCTGCACCAGCACGGCCTCGACCCCGCAAACG
CCAGCGCCCCCGCCGTGCTCGAAGCCGCCCGCATCCGCGAGCGCCGCGAGCAGCTGCAGCCGATGCTGCGCATCGCCGAC
GGCGAAATGCACAGCCTGCATCGGCAGCTGGCCGGCAACGGCCACGTGGTGGTGCTGACCGATGCCGACGGCGTGATCCT
CGACTGCATCGCCGACCACGCGGAGCGCGCCCTGTTCCGGCAGGCCGGCCTGTGGTCCGGCGCCGACTGGAGCGAAGCCC
GCGAAGGCACCAACGGCATCGGCACCTGCGCGGTCGAGCGGCAGGCGCTGACGATCTACCAGGACGAACACTTCCGCAGC
CGCCACATCCGGCTGTCGTGCTCGGCCAGCCCCGTGTTCGATCCGCAGGGCAACCTGCTGGCGGTGCTGGATGTGTCGTC
CATCCCGCGCGAGCTGTCGCGGCAGGGGCAGTTCCATACCACCGCGCTGGTCAACCTCTCGGCCAAGGTGATCGAGGGCG
GGTATTTTCTGCAGCATTTCGAGCGCGACTGGCTGCTGCGCTTCCATGCCCAGCCCGAATACGTCGGGCTGTTCAGCGAG
GGCCTGCTGGCGGTGGGCGGCGACGGACGCATCCGCGCGGCCAACCAGAGCGCGCTGAACCTGCTGGGCCGCACGCGCCA
ATCGCTGCTCGGGCAGCCGGTCGAGACCGTGTTCGACCTGACGGCCGACGCCCTGCTCGCGCGCGCCACCGACAGCGGCG
GCGTGGCCTGGCCGCTGCACACGCATCAGGGTCGCCTGCTGTTCGGCCTGCTGCGCGCGCCCCGCCCGCGCCCGACCGCC
GACGCGGCCCCGGCCTCACCGCCCATGCCGGCCACGCCCGGCCTGTGCCTGCAGGCCGACGGCCTGCGCACCGGCTTCCA
CCGCGCCCTGCGCGTGTTCGAGCACGACGTGCCGCTGCTGCTGCACGGCGAGACCGGCACCGGCAAGGAAGCCTTCGCCC
GCGCCGTGCACCAGGCCAGCAGCCGCGCGGCGCAGCCCTTCGTCGCCGTCAATTGCGCGGCGATTCCCGAGACGCTGATC
GAGAGCGAGCTGTTCGGCTACCGCGGCGGCAGCTTCACCGGCGCGCGCCGGGAAGGCATGCGCGGCAAGCTGCAGCAGGC
CGACGGCGGCACGCTGTTCCTCGACGAGATCGGCGACATGCCGCTGGCGCTGCAGAGCCGGCTGCTGCGCGTGCTGGAGG
AGCGCGCCGTGGTGCCCATCGGTGGCGAGGCGCAGACGGTGGACGTGCGCATCGTCAGCGCCAGCCATCGCGACATGGAA
GCGCGCGTGCGCGACGGCCGCTTCCGCGAAGACCTGTACTACCGCCTCAACGGCCTGCGGATCACGCTGCCGCCGCTGCG
CGAGCGTGCCGACAAGGCCGCGCTGCTGGCGCACGTGCTGGCCGAGGAATCGCGCGGCCGGCCGGCGCGGCTCGACGACG
ATGCGCGCGACGCCCTGCTCGCCCAGCCCTGGCCCGGCAACGTGCGCCAGCTGCGCAATGTGCTGCGCACGCTGGTGGCG
CTGTCCGACGATGGGCGCATCCGCCTGCGCGACCTGCCGCCCGAACTGCGCCCGCCGGCCATGGCATCCGCCGCCGCGCC
CGCGCCGCTGGACAACGCCGAGAAGGCCGCGCTGCTCGCCGCGCTGCAAGCGCAGCAGTGGCGCATGACCCACGCCGCCA
AGGCGCTGGGCATCAGCCGCAACACGCTGTACCGCAAGCTGCGCAAGCACGGCATCGCCCGCCCCGGCGGTTGA

Upstream 100 bases:

>100_bases
GTCGAGCGGGTGTACCGGTTCCGATACGGTGTGCCGGGACACTGTGCTATGTTCAGGACACACGATCCGCCGACCACGGT
GGGCGAAGGAGACAACTGCC

Downstream 100 bases:

>100_bases
CGCACGTCAACCCGGCCCGGCCGCGCATCGACAAGACTGGGGGCTCCCCAACTCCCGGAGATCCGCCATGGCCAGGTCGA
TGAAAGCCGCTGTCGTGCAC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MQDHRMSHHTGQVLTLAQHDAPISGSLSGPAADPSIARSWLRCLHQHGLDPANASAPAVLEAARIRERREQLQPMLRIAD
GEMHSLHRQLAGNGHVVVLTDADGVILDCIADHAERALFRQAGLWSGADWSEAREGTNGIGTCAVERQALTIYQDEHFRS
RHIRLSCSASPVFDPQGNLLAVLDVSSIPRELSRQGQFHTTALVNLSAKVIEGGYFLQHFERDWLLRFHAQPEYVGLFSE
GLLAVGGDGRIRAANQSALNLLGRTRQSLLGQPVETVFDLTADALLARATDSGGVAWPLHTHQGRLLFGLLRAPRPRPTA
DAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLLLHGETGTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLI
ESELFGYRGGSFTGARREGMRGKLQQADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGGEAQTVDVRIVSASHRDME
ARVRDGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESRGRPARLDDDARDALLAQPWPGNVRQLRNVLRTLVA
LSDDGRIRLRDLPPELRPPAMASAAAPAPLDNAEKAALLAALQAQQWRMTHAAKALGISRNTLYRKLRKHGIARPGG

Sequences:

>Translated_637_residues
MQDHRMSHHTGQVLTLAQHDAPISGSLSGPAADPSIARSWLRCLHQHGLDPANASAPAVLEAARIRERREQLQPMLRIAD
GEMHSLHRQLAGNGHVVVLTDADGVILDCIADHAERALFRQAGLWSGADWSEAREGTNGIGTCAVERQALTIYQDEHFRS
RHIRLSCSASPVFDPQGNLLAVLDVSSIPRELSRQGQFHTTALVNLSAKVIEGGYFLQHFERDWLLRFHAQPEYVGLFSE
GLLAVGGDGRIRAANQSALNLLGRTRQSLLGQPVETVFDLTADALLARATDSGGVAWPLHTHQGRLLFGLLRAPRPRPTA
DAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLLLHGETGTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLI
ESELFGYRGGSFTGARREGMRGKLQQADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGGEAQTVDVRIVSASHRDME
ARVRDGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESRGRPARLDDDARDALLAQPWPGNVRQLRNVLRTLVA
LSDDGRIRLRDLPPELRPPAMASAAAPAPLDNAEKAALLAALQAQQWRMTHAAKALGISRNTLYRKLRKHGIARPGG
>Mature_637_residues
MQDHRMSHHTGQVLTLAQHDAPISGSLSGPAADPSIARSWLRCLHQHGLDPANASAPAVLEAARIRERREQLQPMLRIAD
GEMHSLHRQLAGNGHVVVLTDADGVILDCIADHAERALFRQAGLWSGADWSEAREGTNGIGTCAVERQALTIYQDEHFRS
RHIRLSCSASPVFDPQGNLLAVLDVSSIPRELSRQGQFHTTALVNLSAKVIEGGYFLQHFERDWLLRFHAQPEYVGLFSE
GLLAVGGDGRIRAANQSALNLLGRTRQSLLGQPVETVFDLTADALLARATDSGGVAWPLHTHQGRLLFGLLRAPRPRPTA
DAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLLLHGETGTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLI
ESELFGYRGGSFTGARREGMRGKLQQADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGGEAQTVDVRIVSASHRDME
ARVRDGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESRGRPARLDDDARDALLAQPWPGNVRQLRNVLRTLVA
LSDDGRIRLRDLPPELRPPAMASAAAPAPLDNAEKAALLAALQAQQWRMTHAAKALGISRNTLYRKLRKHGIARPGG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=421, Percent_Identity=37.5296912114014, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1788550, Length=291, Percent_Identity=45.0171821305842, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1790437, Length=283, Percent_Identity=45.583038869258, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1790299, Length=333, Percent_Identity=41.7417417417417, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1788905, Length=286, Percent_Identity=45.1048951048951, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1786524, Length=291, Percent_Identity=46.0481099656357, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI87082117, Length=303, Percent_Identity=41.9141914191419, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789087, Length=293, Percent_Identity=39.9317406143345, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082152, Length=253, Percent_Identity=43.0830039525692, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081872, Length=299, Percent_Identity=39.1304347826087, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1787583, Length=289, Percent_Identity=38.0622837370242, Blast_Score=175, Evalue=8e-45,
Organism=Escherichia coli, GI87081858, Length=655, Percent_Identity=26.1068702290076, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=36.6533864541833, Blast_Score=132, Evalue=8e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69467; Mature: 69467

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDHRMSHHTGQVLTLAQHDAPISGSLSGPAADPSIARSWLRCLHQHGLDPANASAPAVL
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
EAARIRERREQLQPMLRIADGEMHSLHRQLAGNGHVVVLTDADGVILDCIADHAERALFR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
QAGLWSGADWSEAREGTNGIGTCAVERQALTIYQDEHFRSRHIRLSCSASPVFDPQGNLL
HCCCCCCCCHHHHHCCCCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEE
AVLDVSSIPRELSRQGQFHTTALVNLSAKVIEGGYFLQHFERDWLLRFHAQPEYVGLFSE
EEEECHHHHHHHHHCCCEEEEEEEECHHHHHCCCHHHHHHCCCEEEEECCCCCEEEEHHC
GLLAVGGDGRIRAANQSALNLLGRTRQSLLGQPVETVFDLTADALLARATDSGGVAWPLH
CEEEECCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
THQGRLLFGLLRAPRPRPTADAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEE
LHGETGTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLIESELFGYRGGSFTGARREGM
EECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
RGKLQQADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGGEAQTVDVRIVSASHRDME
CCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEEEECCCCCHH
ARVRDGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESRGRPARLDDDARDALL
HHHHCCCHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCEE
AQPWPGNVRQLRNVLRTLVALSDDGRIRLRDLPPELRPPAMASAAAPAPLDNAEKAALLA
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHH
ALQAQQWRMTHAAKALGISRNTLYRKLRKHGIARPGG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQDHRMSHHTGQVLTLAQHDAPISGSLSGPAADPSIARSWLRCLHQHGLDPANASAPAVL
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
EAARIRERREQLQPMLRIADGEMHSLHRQLAGNGHVVVLTDADGVILDCIADHAERALFR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
QAGLWSGADWSEAREGTNGIGTCAVERQALTIYQDEHFRSRHIRLSCSASPVFDPQGNLL
HCCCCCCCCHHHHHCCCCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEE
AVLDVSSIPRELSRQGQFHTTALVNLSAKVIEGGYFLQHFERDWLLRFHAQPEYVGLFSE
EEEECHHHHHHHHHCCCEEEEEEEECHHHHHCCCHHHHHHCCCEEEEECCCCCEEEEHHC
GLLAVGGDGRIRAANQSALNLLGRTRQSLLGQPVETVFDLTADALLARATDSGGVAWPLH
CEEEECCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
THQGRLLFGLLRAPRPRPTADAAPASPPMPATPGLCLQADGLRTGFHRALRVFEHDVPLL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEE
LHGETGTGKEAFARAVHQASSRAAQPFVAVNCAAIPETLIESELFGYRGGSFTGARREGM
EECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHCCC
RGKLQQADGGTLFLDEIGDMPLALQSRLLRVLEERAVVPIGGEAQTVDVRIVSASHRDME
CCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEEEECCCCCHH
ARVRDGRFREDLYYRLNGLRITLPPLRERADKAALLAHVLAEESRGRPARLDDDARDALL
HHHHCCCHHHHHHHEECCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCEE
AQPWPGNVRQLRNVLRTLVALSDDGRIRLRDLPPELRPPAMASAAAPAPLDNAEKAALLA
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHH
ALQAQQWRMTHAAKALGISRNTLYRKLRKHGIARPGG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]