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The map label for this gene is rpoB [H]

Identifier: 17547753

GI number: 17547753

Start: 3263489

End: 3267595

Strand: Reverse

Name: rpoB [H]

Synonym: RSc3034

Alternate gene names: 17547753

Gene position: 3267595-3263489 (Counterclockwise)

Preceding gene: 17547754

Following gene: 17547752

Centisome position: 87.92

GC content: 63.18

Gene sequence:

>4107_bases
ATGGCGTACAGCTTTACCGAGAAAAAGCGTATTCGCAAGAGTTTCGCGAAGCGCGCAACGGTCCATCAGGTTCCCTTCCT
GCTTGCCACCCAGATTCAATCGTATGCCCAGTTCTTGCAGGAGCATGCGTCCGTCGCACAGCGAAAGAGCGAAGGCCTGC
AAGCGGCGTTCAACGCCATCTTCCCCATCGTGTCGCACAATGGTCTGGCACGCATGGAATTCGTGTCGTACCACCTGTCC
AACCCGCCGTTCGACGTCAAGGAATGTCAACAGCGCGGTCTGACTTTCCACTCGGCGCTGCGCGCGAAAGTGCGCCTGAT
CATCAACGACCGCGAGAACCCGACCAAGGTCAAGGAGATCAAGGAGCAGGAAGTCTACATGGGCGAGATCCCGCTCATGA
CGTCGACCGGTTCGTTCGTGATCAACGGCACGGAACGCGTGATCGTGTCCCAGCTGCACCGCTCGCCGGGCGTGTTCTTC
GAGCACGACAAGGGCAAGACGCATAGCTCGGGCAAGCTGCTGTTCTCGGCGCGCATCATTCCCTACCGCGGCTCGTGGCT
GGACTTCGAATTCGATCCGAAGGACATCCTGTACTTCCGCGTCGACCGCCGCCGCAAGATGCCGGTGACGATCCTGCTGA
AGTCGATCGGCCTGACGCCGGAACAGATCCTGGCGCACTTCTTCGTCTTCGACAACTTCACGCTCAAGAGCGACGGCGCG
CTGATGGAGTTCGTGCCCGAGCGCCTGCGCGGCGAAGTCGCCCGCTTCGACATCTCCGACAAGAACGGCAAGGTCGTCGT
CGAGAAGGACAAGCGCATCAACGCCAAGCACATCCGTGACCTGGATGCCGCCGGCACCAAGCTGATCAGCGTGCCGGAAG
ACTACCTGCTGGGCCGTGTGCTGGCGAAGAACATCGTCGACCCGGATACCGGCGAAGTGCTGGCCAACGCCAACGACGAG
CTGACCGAAGGCGTGCTCGAGAAGCTGCGTGACGCGGGCGTGAAGGAAATCCAGACGCTGTACACCAACGATCTGGACCA
GGGGCCGTACATGTCGCAGACGCTGCGCACGGACGACACGGTCGACCAGACCGCCGCCCGTATCGCCATCTACCGCATGA
TGCGCCCGGGCGAGCCGCCGACCGAGGACGCCGTCGAAGCGCTGTTCCAGCGCCTGTTCTACAGCGAAGACTCGTACGAT
CTGTCGCGCGTGGGCCGCATGAAGGTCAACAGCCGTCTGAACCGCTCGGAGGGCACCGGCCCGATGGTGCTGACGGATGA
CGACATCCTCGACACCATCAAGCTGCTGGTGAACCTGCGCAACGGCAAGGGCGAAGTGGACGACATCGACCACCTCGGCA
ACCGTCGCGTGCGTTGCGTCGGCGAACTGGCGGAAAACCAGTTCCGCGCCGGTCTGTCGCGCGTCGAGCGCGCGGTCAAG
GAGCGCCTCGGCCAGGCCGAGACGGAAAACCTGATGCCGCACGACCTGATCAACTCGAAGCCGATCTCGTCGGCGATTCG
CGAGTTCTTCGGTTCGTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTGTCGGAAGTGACCCACAAGCGCCGGA
TCTCGGCACTGGGCCCGGGCGGTCTGACGCGCGAGCGCGCGGGCTTCGAAGTCCGCGACGTGCACCCGACCCACTACGGC
CGCGTGTGCCCGATCGAAACGCCGGAAGGTCCGAACATCGGTCTGATCAACTCGCTGGCACTGTACGCGCAGCTCAACGA
CTACGGCTTCCTGGAAACCCCGTACCGCAAGGTCGAGAACAGCAAGCTGACCGACCAGGTCGACTACCTGTCGGCCATCG
AGGAAGGCAAGTACGTGGTGGCGCAGGCCAACGCGACGGTGGACAAGGACGGCAACCTGGTTGACGAACTGGTCTCCGCA
CGTGAAGGCAGCGAGCGTGAAACGCGTATGGTCACGCCGGACCGCGTGCAATACATCGACGTGGCGCCGTCGCAGATCGT
GTCGGCCGCAGCTTCGCTGGTGCCGTTCCTGGAGCACGATGACGCGAACCGTGCACTGATGGGCGCAAACATGCAGCGGC
AGGCCGTGCCTTGCCTGCGTGCGGACAAGCCGCTGGTCGGTACCGGCGTGGAACGCACCGTGGCGGTTGACTCGGGTACC
GCCGTGCAGGCCACCCGTGGCGGCCTGGTCGACTACGTCGACGCCAACCGCGTGGTGATCCGCGTGAACGATGACGAAGC
CGTGGCGGGTGAAGTCGGCGTCGACATCTACAACCTGATCAAGTACACGCGTTCGAACCAGAACACGAACATCAACCAGC
GTCCGATGGTCAAGGTGGGCGATATCGTTGCCCGCGGCGACGTGATCGCCGATGGCGCCTCGACCGACCTGGGCGAGCTC
GCGCTCGGCCAGAACATGCTGGTCGCGTTCATGCCCTGGAACGGCTACAACTTCGAGGATTCGATCCTGATCTCGGAGCG
TGTCGTGGCTGAAGACCGTTACACCTCGATCCACATCGAGGAACTGTCGGTCGTCGCCCGCGACACCAAGCTCGGACCGG
AAGAAATCACGCGCGACATCTCGAACCTGGCTGAAGCCCAACTGGCGCGCCTGGACGAATCGGGCATCACGTACATCGGC
GCGGAAGTCGAAGCCGGCGACGTGATGGTCGGCAAGGTCACGCCCAAGGGCGAGACCCAGCTGACGCCGGAAGAGAAGCT
GCTGCGTGCGATCTTCGGCGAGAAGGCGTCCGACGTGAAGGACACCTCGCTGCGCGTGCCTTCGGGCATGAGCGGTACCG
TGATCGACGTGCAGGTCTTCACGCGTGAAGGCGTGACGCGCGACAAGCGCGCCCAGTCGATCATCGACGAAGAGCTGAAG
CGTTACCGCCTGGACCTGAACGACCAGCTGCGTATCGTGGAAGGCGATGCCTTCCAGCGTCTGGAGCGTCTGCTGGTGGG
CAAGGTCGTCAATGGCGGCCCGAAGAAGCTGGCCAAGGGCACGGCACTCACGAAGGAATACCTGGCCGACCTCGACAAGT
GGCACTGGTTCGACATCCGCCCGTCGGATGACGACGTCGCGACCCAGCTCGAAGCCGTGAAGGAAGCCATCGAGCAGAAG
CGCCACGACTTCGACCTCGCGTTCGAAGAGAAGCGCAAGAAGCTCACGCAGGGCGACGAACTGCCGCCGGGCGTGATCAA
GATGGTCAAGGTGTACCTGGCCGTGAAACGTCGCCTGCAGCCTGGCGACAAGATGGCCGGCCGTCACGGCAACAAGGGCG
TGGTGTCGAAGATCACCCCGATCGAAGACATGCCCTACATGGCCGACGGCACGCCTGCCGACATCGTGCTGAACCCGCTG
GGCGTGCCTTCGCGGATGAACGTGGGCCAGATTCTCGAGACCCACCTGGGCTGGGCCGCGCGTGGCCTGGGCGAGCGCAT
CGGCAACATGCTCAAGGCGCAAGCCAAGGCCGCCGAGATGCGCAAGCTGCTGGGCCAGATCTACAACGAAAGCGGCAAGG
TGGAAGACCTCGATAGCCTGTCCGACGCGGAAGTGCTGGAACTGGCCGAGAACCTGAAGAAGGGCGTGCCGTTCGCGACG
CCGGTGTTCGACGGTGCGCATGAGGACGAAATCCGCCGCATGCTGGACCTCGCCTATCCGGAAGACATCGCGAAGGAGAA
GGGCCTGACGGCTTCCAAGCAGCAGGTCACGCTGTTCGACGGCCGCACCGGTGAAGCGTTCGAGCGTCCGGTCACGTTGG
GTGTGATGCACATGCTGAAGCTGCACCACTTGGTCGACGACAAGATGCACGCGCGTTCGACCGGCCCGTACTCGCTGGTG
ACGCAGCAGCCGCTGGGCGGTAAGGCCCAGTTCGGTGGCCAGCGTTTCGGTGAGATGGAAGTGTGGGCGCTGGAAGCGTA
CGGCGCGTCCTACGTGCTGCAGGAAATGCTGACCGTGAAGTCGGATGACGTGAACGGCCGGACCAAGGTGTACGAGAACA
TCGTCAAGGGCGAGCACTCGATCGATGCCGGCATGCCGGAATCGTTCAATGTGCTGGTGAAGGAAATCCGCTCGCTGGGT
ATCGACATCGACCTCGAGCGCAACTAA

Upstream 100 bases:

>100_bases
CCAACCGCCAAATCCCGTCACCAGTCGCTGAACACCTCAAGTGCCAGGCGTGTCCATCGCCCATGTCCGTCGCGCGCACT
TGCGATGATTCGGAGATCCC

Downstream 100 bases:

>100_bases
GCCGCCGGTGGGATGGGGGCGTGGCAGCGGTATCGCCACGCTCCGGTAACAGCAGCCATTGACGAAGATTTAGGGCCGGT
GCCCCTGGGGCGCCAGCCTC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1368; Mature: 1367

Protein sequence:

>1368_residues
MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQEHASVAQRKSEGLQAAFNAIFPIVSHNGLARMEFVSYHLS
NPPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEIKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFF
EHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGA
LMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLISVPEDYLLGRVLAKNIVDPDTGEVLANANDE
LTEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSQTLRTDDTVDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYD
LSRVGRMKVNSRLNRSEGTGPMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVK
ERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVENSKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSA
REGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGT
AVQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDIVARGDVIADGASTDLGEL
ALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIG
AEVEAGDVMVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKRAQSIIDEELK
RYRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLADLDKWHWFDIRPSDDDVATQLEAVKEAIEQK
RHDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPL
GVPSRMNVGQILETHLGWAARGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAENLKKGVPFAT
PVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLG
IDIDLERN

Sequences:

>Translated_1368_residues
MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQEHASVAQRKSEGLQAAFNAIFPIVSHNGLARMEFVSYHLS
NPPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEIKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFF
EHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGA
LMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLISVPEDYLLGRVLAKNIVDPDTGEVLANANDE
LTEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSQTLRTDDTVDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYD
LSRVGRMKVNSRLNRSEGTGPMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVK
ERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVENSKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSA
REGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGT
AVQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDIVARGDVIADGASTDLGEL
ALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIG
AEVEAGDVMVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKRAQSIIDEELK
RYRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLADLDKWHWFDIRPSDDDVATQLEAVKEAIEQK
RHDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPL
GVPSRMNVGQILETHLGWAARGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAENLKKGVPFAT
PVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLG
IDIDLERN
>Mature_1367_residues
AYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQEHASVAQRKSEGLQAAFNAIFPIVSHNGLARMEFVSYHLSN
PPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEIKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFE
HDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGAL
MEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLISVPEDYLLGRVLAKNIVDPDTGEVLANANDEL
TEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSQTLRTDDTVDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYDL
SRVGRMKVNSRLNRSEGTGPMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVKE
RLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGR
VCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVENSKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSAR
EGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGTA
VQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDIVARGDVIADGASTDLGELA
LGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGA
EVEAGDVMVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKRAQSIIDEELKR
YRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLADLDKWHWFDIRPSDDDVATQLEAVKEAIEQKR
HDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPLG
VPSRMNVGQILETHLGWAARGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAENLKKGVPFATP
VFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLVT
QQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGI
DIDLERN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908503, Length=304, Percent_Identity=30.9210526315789, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI238908505, Length=304, Percent_Identity=30.9210526315789, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI4505941, Length=311, Percent_Identity=27.6527331189711, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI33469941, Length=266, Percent_Identity=30.8270676691729, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI212286172, Length=266, Percent_Identity=30.8270676691729, Blast_Score=91, Evalue=1e-17,
Organism=Escherichia coli, GI1790419, Length=1370, Percent_Identity=65.4014598540146, Blast_Score=1837, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=311, Percent_Identity=27.9742765273312, Blast_Score=113, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17506623, Length=242, Percent_Identity=30.9917355371901, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144348, Length=312, Percent_Identity=27.2435897435897, Blast_Score=81, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=29.5719844357977, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325267, Length=257, Percent_Identity=30.7392996108949, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=304, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17647877, Length=304, Percent_Identity=29.6052631578947, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136444, Length=256, Percent_Identity=29.296875, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136446, Length=260, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=9e-21,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 152430; Mature: 152299

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQEHASVAQRKSEGLQAAFNAI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPIVSHNGLARMEFVSYHLSNPPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEI
HHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHEEEEEEECCCCCHHHHHH
KEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARII
HHHHHEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEE
PYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGA
EECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCC
LMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLISVPEDYLLGRV
HHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHH
LAKNIVDPDTGEVLANANDELTEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSQTLRTDDT
HHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHCCCCH
VDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYDLSRVGRMKVNSRLNRSEGTG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVK
CEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPG
HHHCCCHHHCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVEN
CCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCHHHHCC
SKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSAREGSERETRMVTPDRVQYID
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
VAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGT
CCHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHCCHHHCCCCCCCCCCCEEEEECCCC
AVQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVG
EEEECCCCEEEEECCCEEEEEECCCCCCCCHHCHHHHHHHHHHHCCCCCCCCCCCCEECC
DIVARGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIE
CEEECCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCEEEHH
ELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVMVGKVTPKGETQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCCEEEEEECCCCCCC
LTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKRAQSIIDEELK
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
RYRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLADLDKWHWFDIR
HHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
PSDDDVATQLEAVKEAIEQKRHDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQ
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPLGVPSRMNVGQILETHLGWAA
CCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHHHHH
RGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAENLKKGVPFAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCC
PVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLK
CCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
LHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVK
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLERN
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
AYSFTEKKRIRKSFAKRATVHQVPFLLATQIQSYAQFLQEHASVAQRKSEGLQAAFNAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPIVSHNGLARMEFVSYHLSNPPFDVKECQQRGLTFHSALRAKVRLIINDRENPTKVKEI
HHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHEEEEEEECCCCCHHHHHH
KEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARII
HHHHHEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEE
PYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLKSDGA
EECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCC
LMEFVPERLRGEVARFDISDKNGKVVVEKDKRINAKHIRDLDAAGTKLISVPEDYLLGRV
HHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCHHHHHHHH
LAKNIVDPDTGEVLANANDELTEGVLEKLRDAGVKEIQTLYTNDLDQGPYMSQTLRTDDT
HHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHCCCCH
VDQTAARIAIYRMMRPGEPPTEDAVEALFQRLFYSEDSYDLSRVGRMKVNSRLNRSEGTG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
PMVLTDDDILDTIKLLVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVK
CEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEVTHKRRISALGPG
HHHCCCHHHCCCCHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAQLNDYGFLETPYRKVEN
CCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCCHHHHCC
SKLTDQVDYLSAIEEGKYVVAQANATVDKDGNLVDELVSAREGSERETRMVTPDRVQYID
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEE
VAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRADKPLVGTGVERTVAVDSGT
CCHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHCCHHHCCCCCCCCCCCEEEEECCCC
AVQATRGGLVDYVDANRVVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVG
EEEECCCCEEEEECCCEEEEEECCCCCCCCHHCHHHHHHHHHHHCCCCCCCCCCCCEECC
DIVARGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIE
CEEECCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCEEEHH
ELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVMVGKVTPKGETQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECEECCCCEEEEEECCCCCCC
LTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGVTRDKRAQSIIDEELK
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
RYRLDLNDQLRIVEGDAFQRLERLLVGKVVNGGPKKLAKGTALTKEYLADLDKWHWFDIR
HHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
PSDDDVATQLEAVKEAIEQKRHDFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQ
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PGDKMAGRHGNKGVVSKITPIEDMPYMADGTPADIVLNPLGVPSRMNVGQILETHLGWAA
CCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHHHHHHH
RGLGERIGNMLKAQAKAAEMRKLLGQIYNESGKVEDLDSLSDAEVLELAENLKKGVPFAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCC
PVFDGAHEDEIRRMLDLAYPEDIAKEKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLK
CCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHH
LHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVK
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHC
SDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLERN
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA