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The map label for this gene is rpoC [H]

Identifier: 17547752

GI number: 17547752

Start: 3259141

End: 3263370

Strand: Reverse

Name: rpoC [H]

Synonym: RSc3033

Alternate gene names: 17547752

Gene position: 3263370-3259141 (Counterclockwise)

Preceding gene: 17547753

Following gene: 17547751

Centisome position: 87.81

GC content: 64.0

Gene sequence:

>4230_bases
ATGAAAGCATTGCTCGACCTATTCCGTCAGGTACAGCAAGAAGAGCAGTTCGACGCGATCAAGATCGGCCTCGCATCGCC
CGAGAAAATCCGTTCGTGGTCGTTCGGCGAGGTCAAGAAGCCTGAGACCATCAACTACCGCACGTTCAAGCCGGAGCGTG
ACGGCCTGTTCTGCGCCAAGATCTTCGGCCCGATCAAGGACTACGAGTGCCTGTGCGGCAAGTACAAGCGCCTGAAGCAC
CGTGGTGTGATCTGCGAGAAGTGCGGCGTGGAAGTGACGCTGGCCAAGGTGCGCCGCGAGCGCATGGGCCACATCGAACT
GGCTGCGCCGACCGCGCACATCTGGTTCCTGAAGTCGCTGCCGTCGCGTCTGGGCATGGTGCTCGACATGACGCTGCGCG
ACATCGAGCGCGTGCTGTACTTCGAAGCGTTCGTGGTGGTCGAACCGGGCATGACGCCGCTCAAGAAGAGCCAGATCATG
TCGGAAGACGATTACCTGGCCAAGTGCGACGAGTACGGCGAGGGTGAATTCGTCGCCCTGATGGGTGCCGAGGGCATCCG
TGAACTGCTGCGCGGCATCGACATCGAGAAGCAGATCGAGACCATCCGTGCCGAGCTGCAGGCCACGGGCTCGGAAGCCA
AGATCAAGAAGTTCGCCAAGCGCCTGAAGGTGCTCGAGGCGTTCCAGCGTTCGGGCATCAAGCCGGACTGGATGATCCTC
GAAGTGCTGCCGGTGCTGCCGCCCGAGCTGCGTCCGCTGGTGCCGCTGGACGGCGGCCGTTTCGCCACGTCGGACCTGAA
CGACCTGTATCGCCGAGTGATCAACCGGAACAACCGTCTGAAGCGTCTGCTCGAGCTGAAGGCGCCGGAGATCATCGTGC
GCAACGAAAAGCGCATGCTGCAGGAAGCGGTGGACTCGCTGCTGGACAACGGCCGTCGCGGCAAGGCGATGACCGGCGCC
AACAAGCGTCCGCTGAAGTCCCTGGCCGAAATGATCAAGGGCAAGGGCGGCCGTTTCCGTCAGAACCTGCTGGGCAAGCG
CGTGGACTACTCGGGCCGTTCGGTCATCGTGGTGGGCCCGACGCTCAAGCTGCACCAGTGCGGCCTGCCCAAGCTGATGG
CGCTCGAGCTGTTCAAGCCCTTCATCTTCCACAAGCTGGAAACGATGGGCATCGCCACCACCATCAAGGCGGCGAAGAAG
GAAGTGGAAAGCCAGACGCCGGTGGTGTGGGACATCCTCGAAGAGGTGATCCGCGAGCACCCGGTGATGCTGAACCGTGC
GCCGACGCTGCACCGCCTGGGCATCCAGGCGTTCGAGCCGGTGCTGATCGAAGGCAAGGCCATCCAGCTGCACCCGCTGG
TCTGCGCGGCGTTCAACGCCGACTTCGACGGTGACCAGATGGCTGTCCACGTTCCGCTGTCGCTCGAAGCGCAGATGGAA
GCGCGCACGCTGATGCTGGCGTCGAACAACGTACTGTTCCCGGCCAACGGCGATCCGTCGATCGTGCCGTCGCAGGACGT
GGTGCTGGGTCTGTACTACACGACCCGCGACAAGATCAACGGCCGCGGCGAGGGCATGACCTTCGCCGACATCTCGGAAG
TGATCCGCGCCTACGAGAACAAGGAAGTCGAGCTGGCTTCGCGCGTGAACGTGCGGATCACCGAGTACGACCTGGTGAAC
CCGGAAGCCGACGGCGACGCCCGTTTCGCGCCGAAGATCACGCTGCAGGCCACCACGGTCGGCCGCGCGATCCTGTCGGA
GATCCTGCCGAAGGGTCTGCCGTTCTCGGTGCTGAACAAGCCGCTGAAGAAGAAGGAAATCTCGCGCCTGATCAACACGG
CGTTCCGCAAGTGCGGTCTGCGCGAGACGGTGATCTTCGCCGACAAGCTGCTGCAGTCGGGCTTCCGCCTGGCCACGCGC
GCTGGCATCTCGATCGCCATCGACGACATGCTGGTGCCGCCGGCCAAGGAGAAGATCATCTCCGAGGCTGCCGCCAAGGT
GAAGGAATACGACAAGCAGTACATGTCGGGTCTGGTGACGGATCAGGAGCGCTACAACAACGTCGTGGACATCTGGGGCG
CTGCCGGCGACCAGGTGGGCAAGGCGATGATGGAGCAGCTCCAGACCGAAGACGTGGTCGACCGCCACGGCAAGACCGTC
AAGCAAGAGTCGTTCAACTCCATCTACATGATGGCCGACTCGGGCGCACGGGGCTCCGCGGCGCAGATCCGTCAGCTGGC
CGGCATGCGTGGCCTGATGGCCAAGCCGGACGGCTCGATCATCGAAACGCCGATTACCGCGAACTTCCGCGAAGGCCTGA
ACGTTCTGCAGTACTTCATCTCGACCCACGGTGCGCGTAAGGGTCTGGCTGATACGGCACTGAAGACCGCGAACTCGGGT
TACCTGACCCGTCGTCTGGTCGACGTGACGCAGGATCTGGTGGTGGTGGAAGACGATTGCGGCACCTCCAACGGCGTGGC
CATGAAGGCCCTGGTCGAAGGCGGTGAAGTGATCGAAGCCCTGCGCGACCGTATCCTGGGCCGCGTGGTCGTCAACGACG
TGGTGAACCCGGAAACGCAGGAAACCGCGATCGAAGCCGGCACGCTGCTGGACGAAGACCTGGTCGAGCTGATCGATTCG
ATCGGCGTGGACGAGGTCAAGGTCCGCACGCCGCTGACCTGCGACACGCGCTACGGCCTGTGCGCCAAGTGCTACGGCCG
CGATCTGGGCCGCGGCGTGCTGGTGAACTCGGGCGAAGCGGTGGGCGTGATTGCCGCCCAGTCGATCGGCGAGCCGGGCA
CGCAGCTGACCATGCGTACGTTCCACATCGGTGGTGCGGCATCGCGTGCGGCAGTGGCATCGAGCGTGGAAGCCAAGGCG
ACCGGTACCGTGCGCTTCACGGCGACCATGCGTTACGTCACCAACGCGAAGGGCGAGCAGATCGTCATCTCGCGTTCGGG
CGAGGCGCTGATCACCGACGACCACGGCCGCGAGCGTGAGCGCCACAAGATCCCGTACGGCGCGACGCTGCTGGTGCACG
ATGGCCAGTCCATCAAGGCCGGCACGCAGCTCGCCACGTGGGATCCGCTGACGCGTCCGATCATTTCGGAGTACTCGGGC
ACCATCAAGTTCGAGAACGTCGAAGAGGGCGTGACCGTCGCCAAGCAGATGGACGAAGTGACCGGCCTGTCGACGCTGGT
GGTGATCGACGCCAAGCGCCGCACCTCGGCCTCGAAGGGCATCCGTCCGCAGGTGAAGCTGCTCGACTCGTCGGGCGCCG
AAGTGAAGATCCCGGGCACGGACCACTCCGTGACCATCGGCTTCCAGGTCGGCGCGCTGATCACCGTGAAGGACGGTCAG
CAGGTGCATGTGGGTGAAGTGCTGGCCCGTATCCCGACCGAATCGCAGAAGACGCGTGACATTACCGGTGGTCTGCCGCG
CGTGGCCGAGCTGTTCGAAGCGCGTTCGCCGAAGGACGCCGCCGTGCTGGCGGAAGTCACCGGCACGACCTCGTTCGGCA
AGGACACCAAGGGCAAGCAGCGCCTGGTGATCACGGACCTCGACGGCAATGCCCACGAGTTCCTGATCGCCAAGGAAAAG
CAGGTGCTGGTGCACGACGGCCAGGTGGTCAACAAGGGCGAGATGATCGTCGAAGGCCCGGCCGACCCGCACGACATCCT
GCGCCTGAAGGGCGTGGAAGAGCTGGCGACCTACATCGTCGACGAAGTGCAGGACGTGTACCGTCTGCAGGGCGTGAAGA
TCAACGACAAGCACATCGAAGTGATCGTGCGTCAGATGCTGCGCCGCGTGCAGATCGTCGATGTGGGCGACACCAAGTTC
ATCCCGGGTGAACAGGTGGAGCGCTCGGAGCTGCTCGACGAGAACGACAAGGTCATCGCCGAAGGCAAGCGTCCGGCTAC
CTACGAGAACCTGCTGCTGGGTATCACGAAGGCGTCGCTGTCGACCGACAGCTTCATCTCGGCGGCGTCGTTCCAGGAAA
CCACGCGCGTCCTCACCGAAGCCGCCATCATGGGCAAGGTGGACGACCTGCGCGGTCTGAAGGAAAACGTCATCGTCGGC
CGCCTGATCCCGGCCGGTACCGGTCTGGCTTACCACCGTGCCCGCAAGGCCAAGGAAGCCGCCGACCGCGACCGCGCCGC
TGCGATTGCGGAAGAAGAAGCCGCCTCGATCTTCGAGACGCCCGCCGTCCAGCAGGAAGGCGACGCGTAA

Upstream 100 bases:

>100_bases
GCGTGGCAGCGGTATCGCCACGCTCCGGTAACAGCAGCCATTGACGAAGATTTAGGGCCGGTGCCCCTGGGGCGCCAGCC
TCAAACTCAAGGAGTTTGGA

Downstream 100 bases:

>100_bases
GCGCACCGCAGTTCGATCGAAGCCCGGCCTCGTGCCGGGCTTTTTTTTTGCCCGTCCGCCGGAGATTGGCGGTGGCGCCA
CCCGATTTTGAGGGGACGTT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1409; Mature: 1409

Protein sequence:

>1409_residues
MKALLDLFRQVQQEEQFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVALMGAEGIRELLRGIDIEKQIETIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPDWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGRGEGMTFADISEVIRAYENKEVELASRVNVRITEYDLVN
PEADGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEAAAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQTEDVVDRHGKTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVVVNDVVNPETQETAIEAGTLLDEDLVELIDS
IGVDEVKVRTPLTCDTRYGLCAKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTATMRYVTNAKGEQIVISRSGEALITDDHGRERERHKIPYGATLLVHDGQSIKAGTQLATWDPLTRPIISEYSG
TIKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTSASKGIRPQVKLLDSSGAEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVDVGDTKF
IPGEQVERSELLDENDKVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKVDDLRGLKENVIVG
RLIPAGTGLAYHRARKAKEAADRDRAAAIAEEEAASIFETPAVQQEGDA

Sequences:

>Translated_1409_residues
MKALLDLFRQVQQEEQFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVALMGAEGIRELLRGIDIEKQIETIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPDWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGRGEGMTFADISEVIRAYENKEVELASRVNVRITEYDLVN
PEADGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEAAAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQTEDVVDRHGKTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVVVNDVVNPETQETAIEAGTLLDEDLVELIDS
IGVDEVKVRTPLTCDTRYGLCAKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTATMRYVTNAKGEQIVISRSGEALITDDHGRERERHKIPYGATLLVHDGQSIKAGTQLATWDPLTRPIISEYSG
TIKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTSASKGIRPQVKLLDSSGAEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVDVGDTKF
IPGEQVERSELLDENDKVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKVDDLRGLKENVIVG
RLIPAGTGLAYHRARKAKEAADRDRAAAIAEEEAASIFETPAVQQEGDA
>Mature_1409_residues
MKALLDLFRQVQQEEQFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKH
RGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLKKSQIM
SEDDYLAKCDEYGEGEFVALMGAEGIRELLRGIDIEKQIETIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPDWMIL
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGA
NKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKK
EVESQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGRGEGMTFADISEVIRAYENKEVELASRVNVRITEYDLVN
PEADGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATR
AGISIAIDDMLVPPAKEKIISEAAAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQTEDVVDRHGKTV
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSG
YLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEALRDRILGRVVVNDVVNPETQETAIEAGTLLDEDLVELIDS
IGVDEVKVRTPLTCDTRYGLCAKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
TGTVRFTATMRYVTNAKGEQIVISRSGEALITDDHGRERERHKIPYGATLLVHDGQSIKAGTQLATWDPLTRPIISEYSG
TIKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTSASKGIRPQVKLLDSSGAEVKIPGTDHSVTIGFQVGALITVKDGQ
QVHVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVDVGDTKF
IPGEQVERSELLDENDKVIAEGKRPATYENLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKVDDLRGLKENVIVG
RLIPAGTGLAYHRARKAKEAADRDRAAAIAEEEAASIFETPAVQQEGDA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=1101, Percent_Identity=23.1607629427793, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI4505939, Length=935, Percent_Identity=23.8502673796791, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI103471997, Length=597, Percent_Identity=26.2981574539363, Blast_Score=116, Evalue=1e-25,
Organism=Escherichia coli, GI2367335, Length=1402, Percent_Identity=66.262482168331, Blast_Score=1888, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=872, Percent_Identity=24.3119266055046, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71987878, Length=565, Percent_Identity=26.9026548672566, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71998295, Length=360, Percent_Identity=24.4444444444444, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320061, Length=903, Percent_Identity=24.5847176079734, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324690, Length=608, Percent_Identity=25.6578947368421, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281360912, Length=1023, Percent_Identity=24.4379276637341, Blast_Score=187, Evalue=5e-47,
Organism=Drosophila melanogaster, GI17530899, Length=652, Percent_Identity=25.1533742331288, Blast_Score=167, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155079; Mature: 155079

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFRQVQQEEQFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLKKSQIMSEDDYLAKCDEYGEGEFVAL
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCCCCEEEE
MGAEGIRELLRGIDIEKQIETIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPDWMIL
ECCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRML
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHH
QEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECC
TLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKKEVESQTPVVWDILEEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
CEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGRGEGMTFADISEVIRAYEN
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
KEVELASRVNVRITEYDLVNPEADGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNK
CCEEEECCCEEEEEEEEECCCCCCCCCEECCEEEEEEHHHHHHHHHHHCCCCCCHHHHCC
PLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATRAGISIAIDDMLVPPAKEKII
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCHHHHHH
SEAAAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQTEDVVDRHGKTV
HHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCH
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI
HHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEA
HHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHH
LRDRILGRVVVNDVVNPETQETAIEAGTLLDEDLVELIDSIGVDEVKVRTPLTCDTRYGL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCEECCCCCH
CAKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
HHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCC
TGTVRFTATMRYVTNAKGEQIVISRSGEALITDDHGRERERHKIPYGATLLVHDGQSIKA
CCEEEEEEEEEEHHCCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCEEEEEECCCCCCC
GTQLATWDPLTRPIISEYSGTIKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTSASKG
CCEEECCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCC
IRPQVKLLDSSGAEVKIPGTDHSVTIGFQVGALITVKDGQQVHVGEVLARIPTESQKTRD
CCCEEEEECCCCCEEEECCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQIVDVGDTKFIPGEQVERSELLDENDKVIAEGKRPATYENLLLGITKASL
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCHHHHHEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKVDDLRGLKENVIVGRLIPAGTGLAYHRARKAKEA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHH
ADRDRAAAIAEEEAASIFETPAVQQEGDA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKALLDLFRQVQQEEQFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELAAPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHCCCEEEECCCHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEAFVVVEPGMTPLKKSQIMSEDDYLAKCDEYGEGEFVAL
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCCCCEEEE
MGAEGIRELLRGIDIEKQIETIRAELQATGSEAKIKKFAKRLKVLEAFQRSGIKPDWMIL
ECCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
EVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRML
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHH
QEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKGGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECC
TLKLHQCGLPKLMALELFKPFIFHKLETMGIATTIKAAKKEVESQTPVVWDILEEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQME
CEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARTLMLASNNVLFPANGDPSIVPSQDVVLGLYYTTRDKINGRGEGMTFADISEVIRAYEN
EEEEEEECCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
KEVELASRVNVRITEYDLVNPEADGDARFAPKITLQATTVGRAILSEILPKGLPFSVLNK
CCEEEECCCEEEEEEEEECCCCCCCCCEECCEEEEEEHHHHHHHHHHHCCCCCCHHHHCC
PLKKKEISRLINTAFRKCGLRETVIFADKLLQSGFRLATRAGISIAIDDMLVPPAKEKII
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCHHHHHH
SEAAAKVKEYDKQYMSGLVTDQERYNNVVDIWGAAGDQVGKAMMEQLQTEDVVDRHGKTV
HHHHHHHHHHHHHHHHHCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCH
KQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFI
HHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
STHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVIEA
HHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEHHHHHCCHHHHHH
LRDRILGRVVVNDVVNPETQETAIEAGTLLDEDLVELIDSIGVDEVKVRTPLTCDTRYGL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCEECCCCCH
CAKCYGRDLGRGVLVNSGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKA
HHHHHCCCCCCCEEEECCCEEEEEEECCCCCCCCEEEEEEEEECCCHHHHHHHHCCCCCC
TGTVRFTATMRYVTNAKGEQIVISRSGEALITDDHGRERERHKIPYGATLLVHDGQSIKA
CCEEEEEEEEEEHHCCCCCEEEEECCCCEEEECCCCCCHHHCCCCCCEEEEEECCCCCCC
GTQLATWDPLTRPIISEYSGTIKFENVEEGVTVAKQMDEVTGLSTLVVIDAKRRTSASKG
CCEEECCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCC
IRPQVKLLDSSGAEVKIPGTDHSVTIGFQVGALITVKDGQQVHVGEVLARIPTESQKTRD
CCCEEEEECCCCCEEEECCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHCCCCCCCCCC
ITGGLPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEK
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCC
QVLVHDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIVDEVQDVYRLQGVKINDKHIE
EEEEECCEEECCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECHHHHH
VIVRQMLRRVQIVDVGDTKFIPGEQVERSELLDENDKVIAEGKRPATYENLLLGITKASL
HHHHHHHHHEEEEECCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCHHHHHEEEEHHCC
STDSFISAASFQETTRVLTEAAIMGKVDDLRGLKENVIVGRLIPAGTGLAYHRARKAKEA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCEEEEEECCCCCHHHHHHHHHHHH
ADRDRAAAIAEEEAASIFETPAVQQEGDA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA