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The map label for this gene is pilQ [H]

Identifier: 17547690

GI number: 17547690

Start: 3203114

End: 3205258

Strand: Reverse

Name: pilQ [H]

Synonym: RSc2971

Alternate gene names: 17547690

Gene position: 3205258-3203114 (Counterclockwise)

Preceding gene: 17547691

Following gene: 17547689

Centisome position: 86.25

GC content: 64.62

Gene sequence:

>2145_bases
ATGACGATGCGTCGCGTGAAGGGCGGCCTGGTGCAGGCCGTTCGAGTGGCCCGGGGGGGCGCAGTGGCATGGCTTTCGCT
GTGCATGCTGATGGTGGGTGGACAGGCGTTGGCCCAGCAGGCAATCACGGCGCCGGCAAGCAATGCCGTCGAACGCGTGG
AACAAGCCTCGACAGGCGAATCCACCGTGGTGACGGTGACGCTGAAGGACACGCCCGCCCAGAAGCCGGTGGAATTCAGC
ACGCAGCAGCCTGCGCGCATCGCCATCGACTTCTTCGGCACGGCATTCGCCCAGGGGCGTGCCAACTATCAATATGGCGG
CAAGCTGCTGCGCGCGGCCAGCGTGGTGCAGATCGGTGACCGCACCCGCGTCGTGCTGGATCTGGCGCGCCAGTCGCAGT
ACAAGTCCGAGATCCGGGGCAACCAGTACGTGCTGACGCTGGGCGCCGCGCCGACGGCGTCGGCCACCCCGGTGCCGACC
TTCGCCGCGCCCGCGCCGACGGCCGGTGTGGAGCGGCCGTCCGTGCGCAACATCGACTTCCGCCGTGGCGAAGAACTGGC
CGGCCGCGTGGTGGTCGACCTGTCGACGTCCAACTCCGCGATCAACATCGCTCAGCAGGGGCAAAACCTGGTGGTCGATT
TCGCCGGTGCCACGCTGCCGCAATCGCTGCGTCGCCGCTTTGACGTGAGCGACTTCGGCACGCCGGTGCAGGCCATGCGC
GCCACCGACAACGGCACGGGCGCTCGCCTGGTCATCGAGCCGCGCGGCAACTGGCAGTACAGCTCGTACCAGACCGACAC
GCAGTTCGTGGTGGAAGTCCGCCCGACCAAGGAGGACCCGAACAAGCTGATCTCCGGTCCGGGCTATCGCGGGGAGCGCA
TGTCGCTGAACTTCCAGAACATCGACATTCGTTCGCTGCTGCAGGTCTTTGCCGACTTCACCAACCTGAACATCGTCACC
AGCGACAGCGTGACGGGGACCCTGTCGCTGCGTCTGAAGGACGTGCCGTGGGATCAGGCGCTGCAGATCGTGCTGGATTC
CAAGGGCCTGGCCTCGCGCCGCAACGGCAACGTGCTGTGGGTGGCGCCGCGCAACGAACTGGCGACCAAGGAGAAGGCTG
AGCTGGAGTCGCAGCAACAGGTGACCGAGCTGGAGCCGCTGCGCAGCCAGGTGTTCCGTCTGAATTACCAGCGTGCTGAC
GACGTGCGCAACATGCTGCTGGGTACCGGAGGAACGGCGGGCGGTGGTGCTGCGGCGTCGCGCATCTTGTCCAAGCGTGG
CTCGCTGACGTCGGATGCCCGTACCAACCAGCTGTTCGTCTCGGATATCCCGAGCAAGCTGGAGGAGGTGCAGGCCTTCC
TGCTGAAGATCGACATCCCGGTGCGTCAGGTGATGATCGAGGCGCGCATCGTCGAGGCCGATGACACGTTCAGCCGCAAT
CTTGGGGCAAAGCTGGGCTTCGCGGCCAAGACCAATGGTGCCGGGTATGGCAACACCTACAGCAACGTGGTGTCGCCGGT
CACGAAAGACGCTACTTGGGATAACAGCGCGGCCGTCAGCCTGCCCGCCAATGGCATCAACGGTGTGAACGCCGCCAGTG
TGGCAGTGAGCTTGTTCAACGCCGGTGCCGGCCGTTTCCTGGCGCTCGAACTGTCGGCGCTGGAAGCCGATGGCCGCGGC
AAGATCATCTCCAGCCCGCGTGTGGTCACCGCTGACAACATCAAGGCGCTGATCGAGCAGGGTACCGAAGTGCCTTACCA
GCAGGCGACCTCGTCGGGTGCGACGTCGGTTTCGTTCAAAAAGGCCAACCTGAAATTGGAGGTGACGCCGAAGATTACGC
CGGACGGCAACGTGTTCCTGGACGTGGACGTCAACAAGGACAGCCTGGGCACGCAGACCACCAACGGCTTCGCCATCAAC
ACCAAGCATGTGCAGACCCAGGTGTTGGTCGAGAACGGCGGTACGGTTGTGATTGGCGGCATCTACACGCAGAACGAACG
GACCGATGTGAACAAGGTCCCGCTGCTGGGTGACATCCCGGTGCTGGGCAACCTGTTCAAGAGCACGGCCAAGACCAACG
ACCGGACGGAACTGCTGGTGTTCCTGACGCCGCGCGTGCTGTCCGACCAGCTGTCGCTGAAGTAA

Upstream 100 bases:

>100_bases
GCATCGGCGATCAGGAACTCACCCTGCGTGAGCTGGTGCGCGAAGGCACGGCCGAATGGAAAGAAAAAATGACGACCCTG
AAAGTTCAGGAGGGCGCGCA

Downstream 100 bases:

>100_bases
GCCGCAGCGCGGGTGTCCAGACCCGAAGGCCCGGCCTCCGGATGGAGTGCCGGGCTTTTTTTCGTTCGGCGCATCGATCG
GCGCGGGATGCCGGGCAAAA

Product: fimbrial type-4 assembly signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MTMRRVKGGLVQAVRVARGGAVAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGESTVVTVTLKDTPAQKPVEFS
TQQPARIAIDFFGTAFAQGRANYQYGGKLLRAASVVQIGDRTRVVLDLARQSQYKSEIRGNQYVLTLGAAPTASATPVPT
FAAPAPTAGVERPSVRNIDFRRGEELAGRVVVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMR
ATDNGTGARLVIEPRGNWQYSSYQTDTQFVVEVRPTKEDPNKLISGPGYRGERMSLNFQNIDIRSLLQVFADFTNLNIVT
SDSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLWVAPRNELATKEKAELESQQQVTELEPLRSQVFRLNYQRAD
DVRNMLLGTGGTAGGGAAASRILSKRGSLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRN
LGAKLGFAAKTNGAGYGNTYSNVVSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFNAGAGRFLALELSALEADGRG
KIISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFKKANLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAIN
TKHVQTQVLVENGGTVVIGGIYTQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK

Sequences:

>Translated_714_residues
MTMRRVKGGLVQAVRVARGGAVAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGESTVVTVTLKDTPAQKPVEFS
TQQPARIAIDFFGTAFAQGRANYQYGGKLLRAASVVQIGDRTRVVLDLARQSQYKSEIRGNQYVLTLGAAPTASATPVPT
FAAPAPTAGVERPSVRNIDFRRGEELAGRVVVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMR
ATDNGTGARLVIEPRGNWQYSSYQTDTQFVVEVRPTKEDPNKLISGPGYRGERMSLNFQNIDIRSLLQVFADFTNLNIVT
SDSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLWVAPRNELATKEKAELESQQQVTELEPLRSQVFRLNYQRAD
DVRNMLLGTGGTAGGGAAASRILSKRGSLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRN
LGAKLGFAAKTNGAGYGNTYSNVVSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFNAGAGRFLALELSALEADGRG
KIISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFKKANLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAIN
TKHVQTQVLVENGGTVVIGGIYTQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK
>Mature_713_residues
TMRRVKGGLVQAVRVARGGAVAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGESTVVTVTLKDTPAQKPVEFST
QQPARIAIDFFGTAFAQGRANYQYGGKLLRAASVVQIGDRTRVVLDLARQSQYKSEIRGNQYVLTLGAAPTASATPVPTF
AAPAPTAGVERPSVRNIDFRRGEELAGRVVVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMRA
TDNGTGARLVIEPRGNWQYSSYQTDTQFVVEVRPTKEDPNKLISGPGYRGERMSLNFQNIDIRSLLQVFADFTNLNIVTS
DSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLWVAPRNELATKEKAELESQQQVTELEPLRSQVFRLNYQRADD
VRNMLLGTGGTAGGGAAASRILSKRGSLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRNL
GAKLGFAAKTNGAGYGNTYSNVVSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFNAGAGRFLALELSALEADGRGK
IISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFKKANLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAINT
KHVQTQVLVENGGTVVIGGIYTQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=438, Percent_Identity=34.9315068493151, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=30.1047120418848, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 76613; Mature: 76481

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRRVKGGLVQAVRVARGGAVAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGE
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCC
STVVTVTLKDTPAQKPVEFSTQQPARIAIDFFGTAFAQGRANYQYGGKLLRAASVVQIGD
CEEEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCHHCHHHHHHHHEEEECC
RTRVVLDLARQSQYKSEIRGNQYVLTLGAAPTASATPVPTFAAPAPTAGVERPSVRNIDF
CCEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RRGEELAGRVVVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMR
CCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCHHHEE
ATDNGTGARLVIEPRGNWQYSSYQTDTQFVVEVRPTKEDPNKLISGPGYRGERMSLNFQN
ECCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECC
IDIRSLLQVFADFTNLNIVTSDSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLW
CCHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHEEEEEECCCCCCCCCCCCEEE
VAPRNELATKEKAELESQQQVTELEPLRSQVFRLNYQRADDVRNMLLGTGGTAGGGAAAS
EECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCHHHHH
RILSKRGSLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRN
HHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEECCCHHHHEEEEEEEECCCCHHHC
LGAKLGFAAKTNGAGYGNTYSNVVSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFN
CCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHH
AGAGRFLALELSALEADGRGKIISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFK
CCCCEEEEEEEEEECCCCCCCEECCCCEEEHHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
KANLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAINTKHVQTQVLVENGGTVVIGG
ECCEEEEECCEECCCCCEEEEEECCCCCCCCCCCCCEEEEECEEEEEEEEECCCEEEEEE
IYTQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK
EEECCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEEECCHHHCHHHCCC
>Mature Secondary Structure 
TMRRVKGGLVQAVRVARGGAVAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCC
STVVTVTLKDTPAQKPVEFSTQQPARIAIDFFGTAFAQGRANYQYGGKLLRAASVVQIGD
CEEEEEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCHHCHHHHHHHHEEEECC
RTRVVLDLARQSQYKSEIRGNQYVLTLGAAPTASATPVPTFAAPAPTAGVERPSVRNIDF
CCEEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RRGEELAGRVVVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMR
CCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCHHHEE
ATDNGTGARLVIEPRGNWQYSSYQTDTQFVVEVRPTKEDPNKLISGPGYRGERMSLNFQN
ECCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECC
IDIRSLLQVFADFTNLNIVTSDSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLW
CCHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHEEEEEECCCCCCCCCCCCEEE
VAPRNELATKEKAELESQQQVTELEPLRSQVFRLNYQRADDVRNMLLGTGGTAGGGAAAS
EECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCHHHHH
RILSKRGSLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRN
HHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHEECCCHHHHEEEEEEEECCCCHHHC
LGAKLGFAAKTNGAGYGNTYSNVVSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFN
CCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHH
AGAGRFLALELSALEADGRGKIISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFK
CCCCEEEEEEEEEECCCCCCCEECCCCEEEHHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
KANLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAINTKHVQTQVLVENGGTVVIGG
ECCEEEEECCEECCCCCEEEEEECCCCCCCCCCCCCEEEEECEEEEEEEEECCCEEEEEE
IYTQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK
EEECCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEEEEEECCHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]