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The map label for this gene is engD [H]

Identifier: 17547617

GI number: 17547617

Start: 3125421

End: 3126515

Strand: Direct

Name: engD [H]

Synonym: RSc2898

Alternate gene names: 17547617

Gene position: 3125421-3126515 (Clockwise)

Preceding gene: 17547615

Following gene: 17547619

Centisome position: 84.1

GC content: 65.48

Gene sequence:

>1095_bases
ATGAGCCTCCAATGCGGCATCGTCGGTCTGCCGAACGTCGGCAAGTCGACCCTGTTCAATGCCCTGACCAAAGCCGGCAT
CGCCGCCGAGAACTACCCGTTCTGCACCATTGAGCCCAACGTCGGCGTGGTCGAGGTGCCGGACCAGCGCCTGTCCGCCC
TGGCCGACATCGTCAAGCCGGAGCGCGTGCTGCCGGCGGTGGTCGAGTTCGTCGATATCGCAGGCCTGGTGGCGGGCGCG
TCCAAAGGCGAAGGCCTGGGCAACCAGTTCCTGGCCAACATCCGCGAAACGGACGCCATCACCCACGTCGTGCGTTGCTT
CGAAGATGAAAACGTCGTCCACGTGGCCGGCAAGGTGGACCCGATCGCCGACATCGAAGTGATCAACACCGAACTGGCGC
TGGCCGATCTCGCCACGGTGGAAAAAGCCCTGGCGCGCTACAGCAAGGCCGCCAAGTCGGGCAACGACAAGGAAGCCGCC
AAGCTGGTGGCCGTGCTGGAAAAGGCGCGCAGCGTGCTGGACGAGGCCAAGGCCGTGCGCACCCTGAGCCTGTCCGACGA
GGAATGGGCGCTGCTCAAGCCGCTGTGCCTGATCACCGCCAAGCCGACCATGTACGTCGCCAACGTCAAGGACGACGGCT
TCGAGAACAACCCGCACCTGGACGCCGTGCGCGCCTATGCCGCACAGACCGGCTCGCCGGTGGTGGCCGTGTGCGCGGCC
ATCGAGGCCGAGATCGCTGACCTGGACGATGCCGACAAGACCGAGTTCCTGGCCGACATGGGCATGGACGAGCCGGGCCT
GAACCGCGTGATCCGCGCCGCCTTCAAGCTGCTGGGGCTGCAGACCTACTTCACCGCCGGCGTGAAGGAAGTACGCGCCT
GGACCATCCATATCGGCGACACCGCGCCGCGCGCCGCCGCCGCCATCCACACCGACTTCGAGCGCGGCTTCATCCGCGCG
CAGACCATCGCCTACGACGATTTCATCCAGTACAAGGGTGAACAGGGCGCCAAGGAAGCCGGCAAGATGCGGGCCGAAGG
CAAGGAGTACATCGTCAAGGACGGTGACGTGCTGCACTTCCTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
CCGCCCGTCCGCGCGGCATCCCGCCGTGCGCCGGCTGCCCGAATGCGGCCCGGCCGCCCTTGCGGCCTAACCCATTGATC
CAGAAGCCTTTACCCTTACC

Downstream 100 bases:

>100_bases
ACGCCGAAGCGCCCGCCCACGAGCCCCGCACCGCGGGGCTTTTTCGTTTCCGTCGGCGCATGCCGCCGACCGCGGTGCCC
GCTAGCCGCGCAGCAGCCCC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDQRLSALADIVKPERVLPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDENVVHVAGKVDPIADIEVINTELALADLATVEKALARYSKAAKSGNDKEAA
KLVAVLEKARSVLDEAKAVRTLSLSDEEWALLKPLCLITAKPTMYVANVKDDGFENNPHLDAVRAYAAQTGSPVVAVCAA
IEAEIADLDDADKTEFLADMGMDEPGLNRVIRAAFKLLGLQTYFTAGVKEVRAWTIHIGDTAPRAAAAIHTDFERGFIRA
QTIAYDDFIQYKGEQGAKEAGKMRAEGKEYIVKDGDVLHFLFNV

Sequences:

>Translated_364_residues
MSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDQRLSALADIVKPERVLPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDENVVHVAGKVDPIADIEVINTELALADLATVEKALARYSKAAKSGNDKEAA
KLVAVLEKARSVLDEAKAVRTLSLSDEEWALLKPLCLITAKPTMYVANVKDDGFENNPHLDAVRAYAAQTGSPVVAVCAA
IEAEIADLDDADKTEFLADMGMDEPGLNRVIRAAFKLLGLQTYFTAGVKEVRAWTIHIGDTAPRAAAAIHTDFERGFIRA
QTIAYDDFIQYKGEQGAKEAGKMRAEGKEYIVKDGDVLHFLFNV
>Mature_363_residues
SLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDQRLSALADIVKPERVLPAVVEFVDIAGLVAGAS
KGEGLGNQFLANIRETDAITHVVRCFEDENVVHVAGKVDPIADIEVINTELALADLATVEKALARYSKAAKSGNDKEAAK
LVAVLEKARSVLDEAKAVRTLSLSDEEWALLKPLCLITAKPTMYVANVKDDGFENNPHLDAVRAYAAQTGSPVVAVCAAI
EAEIADLDDADKTEFLADMGMDEPGLNRVIRAAFKLLGLQTYFTAGVKEVRAWTIHIGDTAPRAAAAIHTDFERGFIRAQ
TIAYDDFIQYKGEQGAKEAGKMRAEGKEYIVKDGDVLHFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.5474254742547, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI58761502, Length=225, Percent_Identity=35.5555555555556, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=70.6043956043956, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.1639344262295, Blast_Score=290, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=37.6693766937669, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=385, Percent_Identity=33.7662337662338, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321649, Length=207, Percent_Identity=35.7487922705314, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=40.0544959128065, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=40.0544959128065, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=40.0544959128065, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=37.2307692307692, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24585318, Length=137, Percent_Identity=32.8467153284672, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39127; Mature: 38996

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDQRLSALADIVKP
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
ERVLPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDENVVHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIADIEVINTELALADLATVEKALARYSKAAKSGNDKEAAKLVAVLEKARSVLDEAKAVR
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
TLSLSDEEWALLKPLCLITAKPTMYVANVKDDGFENNPHLDAVRAYAAQTGSPVVAVCAA
EECCCCCCHHHHCCHHEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
IEAEIADLDDADKTEFLADMGMDEPGLNRVIRAAFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECC
TAPRAAAAIHTDFERGFIRAQTIAYDDFIQYKGEQGAKEAGKMRAEGKEYIVKDGDVLHF
CCCHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCEEEE
LFNV
EECC
>Mature Secondary Structure 
SLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDQRLSALADIVKP
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHCC
ERVLPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDENVVHVAGKVD
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIADIEVINTELALADLATVEKALARYSKAAKSGNDKEAAKLVAVLEKARSVLDEAKAVR
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
TLSLSDEEWALLKPLCLITAKPTMYVANVKDDGFENNPHLDAVRAYAAQTGSPVVAVCAA
EECCCCCCHHHHCCHHEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
IEAEIADLDDADKTEFLADMGMDEPGLNRVIRAAFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECC
TAPRAAAAIHTDFERGFIRAQTIAYDDFIQYKGEQGAKEAGKMRAEGKEYIVKDGDVLHF
CCCHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEECCCCEEEE
LFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]