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The map label for this gene is hipO [H]

Identifier: 17547590

GI number: 17547590

Start: 3094267

End: 3095457

Strand: Direct

Name: hipO [H]

Synonym: RSc2871

Alternate gene names: 17547590

Gene position: 3094267-3095457 (Clockwise)

Preceding gene: 17547583

Following gene: 17547592

Centisome position: 83.26

GC content: 63.06

Gene sequence:

>1191_bases
ATGAAGCTGATCCCAGAAATCCTCGCCGCCCAGGCAGAGATCCAGGCACTGCGACGTGACATTCATGCCCACCCCGAACT
CTGTTTCGAAGAGCAGCGCACCTCCGACCTGGTCGCCGCCAAGCTGGCCGAATGGGGTATCGAAGTGCACCGTGGACTCG
GCAAGACCGGCCTGGTCGGCGTGATCCGCAACGGTGAAGGCCAACGGATCGGCCTGCGCGCAGACATGGATGCGCTGCCA
TTGGCCGAGGCCAACCAGTTCACACACCGCTCCAGGCACGAAGGAAAAATGCACGCATGCGGCCATGACGGCCACACGGC
CATGCTGCTGGGTGCGGCCCACTATCTCGCCAGGCACCGCAACTTCAGCGGTACGGTCCACCTGATCTTCCAGCCGGCCG
AAGAAGGCGGCGGCGGCGCTCGGGAAATGATCAGGGACGGCCTGTTCGACCGCTTCCCGTGCGACGCGGTGTTCGGCATG
CATAACTGGCCGGGCGTACCCGTCGGCGCATTCGGCACGCGCGTCGGCCCGCTGATGGCATCCAGCAACGAATTCCGCAT
CGTCATCAAAGGCAAGGGCGCACACGCCGCACTGCCGCACAACGGCAACGACCCCGTGTTCGTTGGCGCACAGATGGTAT
CGGCGCTGCAGGGCGTCATCACTCGCAACAAGCGGCCGATCGACACGGCGGTGCTGTCCATCACGCAGTTCCATGCCGGC
GACGCCAGCAACATCATCCCGAACGAAGCGTGGATCGGCGGCACCGTGCGCACCTTCTCGACAGCCGTGCTGGACCTGAT
CGAGCGGCGCATGGAAGAAGTCGCCAAAGCGATCGCCGCCGCCTACGACTGCTCCATCGACTTCACCTTCCATCGCAACT
ACCCGCCCACCGTCAACACCGAGCGGGAAACGCTGTTCGCCGCCGAAGTCATGCGCGAACTGGTCGGCCCCGATCACGTC
GATGCCAATATCGACCCGACCATGGGAGCCGAGGATTTCTCCTTCATGCTGATCGAGAAACCGGGCTGCTTTGCCTTCAT
CGGCAACGGCGACGGCGATCATCGAGAACAAGGCCACGGCCTGGGACCGTGCATGCTGCACAATCCCAGCTACGACTTCA
ACGACGAACTGCTGCCGCTCGGCGCAACTTACTGGGTTCGCCTGGTAGAAAAATTTTTGGCTCCAGCTTGA

Upstream 100 bases:

>100_bases
GGCGTGCCGCGCTCGCACGGATGGCGCGGACCAGGCAGCCACCTTCGGCGTATCATCGGACGTTGAAGCGAACTTCCACG
CCAGAACACGAGCGCCACCC

Downstream 100 bases:

>100_bases
TTCACGCATCTCCTCAGAAACACAAAAACCACCGTGCACGGTGGGTTTTTTATGATCCGCAGAAAAGTTGCTCGCCGCAG
TTGGGGACGCGTATCCGCGA

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKLIPEILAAQAEIQALRRDIHAHPELCFEEQRTSDLVAAKLAEWGIEVHRGLGKTGLVGVIRNGEGQRIGLRADMDALP
LAEANQFTHRSRHEGKMHACGHDGHTAMLLGAAHYLARHRNFSGTVHLIFQPAEEGGGGAREMIRDGLFDRFPCDAVFGM
HNWPGVPVGAFGTRVGPLMASSNEFRIVIKGKGAHAALPHNGNDPVFVGAQMVSALQGVITRNKRPIDTAVLSITQFHAG
DASNIIPNEAWIGGTVRTFSTAVLDLIERRMEEVAKAIAAAYDCSIDFTFHRNYPPTVNTERETLFAAEVMRELVGPDHV
DANIDPTMGAEDFSFMLIEKPGCFAFIGNGDGDHREQGHGLGPCMLHNPSYDFNDELLPLGATYWVRLVEKFLAPA

Sequences:

>Translated_396_residues
MKLIPEILAAQAEIQALRRDIHAHPELCFEEQRTSDLVAAKLAEWGIEVHRGLGKTGLVGVIRNGEGQRIGLRADMDALP
LAEANQFTHRSRHEGKMHACGHDGHTAMLLGAAHYLARHRNFSGTVHLIFQPAEEGGGGAREMIRDGLFDRFPCDAVFGM
HNWPGVPVGAFGTRVGPLMASSNEFRIVIKGKGAHAALPHNGNDPVFVGAQMVSALQGVITRNKRPIDTAVLSITQFHAG
DASNIIPNEAWIGGTVRTFSTAVLDLIERRMEEVAKAIAAAYDCSIDFTFHRNYPPTVNTERETLFAAEVMRELVGPDHV
DANIDPTMGAEDFSFMLIEKPGCFAFIGNGDGDHREQGHGLGPCMLHNPSYDFNDELLPLGATYWVRLVEKFLAPA
>Mature_396_residues
MKLIPEILAAQAEIQALRRDIHAHPELCFEEQRTSDLVAAKLAEWGIEVHRGLGKTGLVGVIRNGEGQRIGLRADMDALP
LAEANQFTHRSRHEGKMHACGHDGHTAMLLGAAHYLARHRNFSGTVHLIFQPAEEGGGGAREMIRDGLFDRFPCDAVFGM
HNWPGVPVGAFGTRVGPLMASSNEFRIVIKGKGAHAALPHNGNDPVFVGAQMVSALQGVITRNKRPIDTAVLSITQFHAG
DASNIIPNEAWIGGTVRTFSTAVLDLIERRMEEVAKAIAAAYDCSIDFTFHRNYPPTVNTERETLFAAEVMRELVGPDHV
DANIDPTMGAEDFSFMLIEKPGCFAFIGNGDGDHREQGHGLGPCMLHNPSYDFNDELLPLGATYWVRLVEKFLAPA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=427, Percent_Identity=25.5269320843091, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43250; Mature: 43250

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIPEILAAQAEIQALRRDIHAHPELCFEEQRTSDLVAAKLAEWGIEVHRGLGKTGLVG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VIRNGEGQRIGLRADMDALPLAEANQFTHRSRHEGKMHACGHDGHTAMLLGAAHYLARHR
EEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHC
NFSGTVHLIFQPAEEGGGGAREMIRDGLFDRFPCDAVFGMHNWPGVPVGAFGTRVGPLMA
CCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCCEE
SSNEFRIVIKGKGAHAALPHNGNDPVFVGAQMVSALQGVITRNKRPIDTAVLSITQFHAG
CCCCEEEEEEECCCEEECCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DASNIIPNEAWIGGTVRTFSTAVLDLIERRMEEVAKAIAAAYDCSIDFTFHRNYPPTVNT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
ERETLFAAEVMRELVGPDHVDANIDPTMGAEDFSFMLIEKPGCFAFIGNGDGDHREQGHG
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHCCCC
LGPCMLHNPSYDFNDELLPLGATYWVRLVEKFLAPA
CCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLIPEILAAQAEIQALRRDIHAHPELCFEEQRTSDLVAAKLAEWGIEVHRGLGKTGLVG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VIRNGEGQRIGLRADMDALPLAEANQFTHRSRHEGKMHACGHDGHTAMLLGAAHYLARHR
EEECCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHC
NFSGTVHLIFQPAEEGGGGAREMIRDGLFDRFPCDAVFGMHNWPGVPVGAFGTRVGPLMA
CCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCCEE
SSNEFRIVIKGKGAHAALPHNGNDPVFVGAQMVSALQGVITRNKRPIDTAVLSITQFHAG
CCCCEEEEEEECCCEEECCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
DASNIIPNEAWIGGTVRTFSTAVLDLIERRMEEVAKAIAAAYDCSIDFTFHRNYPPTVNT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
ERETLFAAEVMRELVGPDHVDANIDPTMGAEDFSFMLIEKPGCFAFIGNGDGDHREQGHG
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHCCCC
LGPCMLHNPSYDFNDELLPLGATYWVRLVEKFLAPA
CCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]