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The map label for this gene is fruK [H]

Identifier: 17547581

GI number: 17547581

Start: 3084123

End: 3085073

Strand: Direct

Name: fruK [H]

Synonym: RSc2862

Alternate gene names: 17547581

Gene position: 3084123-3085073 (Clockwise)

Preceding gene: 17547580

Following gene: 17547582

Centisome position: 82.99

GC content: 72.34

Gene sequence:

>951_bases
ATGACCCAGCGCATCGTCACCGTCACCCTGAATCCGGCCATCGACATGACGGTCGGCCTGGATCGGCTCGAACGCGGCCA
TGTCAACCTCGGCCGCAGCGTCACGCACCAGGCCGGCGGCAAGGGCGTCAACGTGGCCGGCTGCCTGGCCGACTGGCAGG
TGCCCGTGGTGGCCACCGGCCTGCTGGGCGAAGCCAATACCGAACTGTTCGAAGCGCTGTTCGCGCGCAAGGGCATGGCA
GACGGCTTCTGCCGCGTGCCCGGCACCAACCGCACCAATATCAAGATCAGCGATCAGTCCGACGGGCAGACCACCGACAT
CAACCTGCCCGGGATCACGGCAGCGCCCGCGGACCTCGACGCCGTCTGCGAGCGCGTCGATGCGGTGGCTGACGTGGCAG
GCATCGCGCTGTGCGGCAGCCTTGCGGGCGGCTTGCCCGCCGACACCTACGTCCGCCTGCTGGCACGCCTGAACCGGCGC
GGCGCGCGCACGCTGCTCGACACCAGCGGCGCGCCGCTCACGCACGCCCTGGCCGCACCGCGCGAAGCCCTGCCCACCGC
GATCAAGCCCAACCGGCACGAACTGGAACTGTGGGCCGGCAGGCCGCTGCCGGCGCTGCAGGATGTGGTGGATGCCGCGC
GCGGCATCCACGCGCGCGGCGTGGCGCAGGTCATCGTCTCGCTGGGCGAGCAAGGCGCCCTGTTCGTGACCGGCGAAGGC
ATCTGGCAGGCCAGTCTGCCGCCGGTGCGCGCCGCCAGCACGGTCGGCGCGGGCGATGCCATGGTGGCCGGCGTGCTGGC
CGGCTGGCACGCCGGCGCCTCGACCGAAGAGACCGTCCGCCTGTCGGTGGCGTTTGCCGCCTGCAAGCTGCAGCGCATCG
GCCCCCACCTGCCGCCGCCGCAGCAAGTACGCGAGCGCGCCGCCGCCGTGCACATGCAGCGGGTGGCCTGA

Upstream 100 bases:

>100_bases
AGCTGGCCGGGCAGGCGCTCGCCTGCGCATCGGCCGAAGACGTGCGGGCGCTCGAAGCCACCCTCCCCGCTCATCGCGCC
GGCACGGAGATGGCCGCAGC

Downstream 100 bases:

>100_bases
CGCCCCGCTCAACCGATTCCAAGGAGCTAGACATGCCCCATCTGTTGGCAATTCTCGGCGCGGACAGCCACAGCACGCGC
CCCCTGCTGGCCGGCGAAGC

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTQRIVTVTLNPAIDMTVGLDRLERGHVNLGRSVTHQAGGKGVNVAGCLADWQVPVVATGLLGEANTELFEALFARKGMA
DGFCRVPGTNRTNIKISDQSDGQTTDINLPGITAAPADLDAVCERVDAVADVAGIALCGSLAGGLPADTYVRLLARLNRR
GARTLLDTSGAPLTHALAAPREALPTAIKPNRHELELWAGRPLPALQDVVDAARGIHARGVAQVIVSLGEQGALFVTGEG
IWQASLPPVRAASTVGAGDAMVAGVLAGWHAGASTEETVRLSVAFAACKLQRIGPHLPPPQQVRERAAAVHMQRVA

Sequences:

>Translated_316_residues
MTQRIVTVTLNPAIDMTVGLDRLERGHVNLGRSVTHQAGGKGVNVAGCLADWQVPVVATGLLGEANTELFEALFARKGMA
DGFCRVPGTNRTNIKISDQSDGQTTDINLPGITAAPADLDAVCERVDAVADVAGIALCGSLAGGLPADTYVRLLARLNRR
GARTLLDTSGAPLTHALAAPREALPTAIKPNRHELELWAGRPLPALQDVVDAARGIHARGVAQVIVSLGEQGALFVTGEG
IWQASLPPVRAASTVGAGDAMVAGVLAGWHAGASTEETVRLSVAFAACKLQRIGPHLPPPQQVRERAAAVHMQRVA
>Mature_315_residues
TQRIVTVTLNPAIDMTVGLDRLERGHVNLGRSVTHQAGGKGVNVAGCLADWQVPVVATGLLGEANTELFEALFARKGMAD
GFCRVPGTNRTNIKISDQSDGQTTDINLPGITAAPADLDAVCERVDAVADVAGIALCGSLAGGLPADTYVRLLARLNRRG
ARTLLDTSGAPLTHALAAPREALPTAIKPNRHELELWAGRPLPALQDVVDAARGIHARGVAQVIVSLGEQGALFVTGEGI
WQASLPPVRAASTVGAGDAMVAGVLAGWHAGASTEETVRLSVAFAACKLQRIGPHLPPPQQVRERAAAVHMQRVA

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=281, Percent_Identity=39.1459074733096, Blast_Score=203, Evalue=9e-54,
Organism=Escherichia coli, GI1788017, Length=283, Percent_Identity=32.5088339222615, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32877; Mature: 32746

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRIVTVTLNPAIDMTVGLDRLERGHVNLGRSVTHQAGGKGVNVAGCLADWQVPVVATG
CCCEEEEEEECCCEEEEECHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHCCCCCCEEEEC
LLGEANTELFEALFARKGMADGFCRVPGTNRTNIKISDQSDGQTTDINLPGITAAPADLD
CCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHH
AVCERVDAVADVAGIALCGSLAGGLPADTYVRLLARLNRRGARTLLDTSGAPLTHALAAP
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHCC
REALPTAIKPNRHELELWAGRPLPALQDVVDAARGIHARGVAQVIVSLGEQGALFVTGEG
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCC
IWQASLPPVRAASTVGAGDAMVAGVLAGWHAGASTEETVRLSVAFAACKLQRIGPHLPPP
EEECCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHHHHCCCCCCH
QQVRERAAAVHMQRVA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQRIVTVTLNPAIDMTVGLDRLERGHVNLGRSVTHQAGGKGVNVAGCLADWQVPVVATG
CCEEEEEEECCCEEEEECHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHCCCCCCEEEEC
LLGEANTELFEALFARKGMADGFCRVPGTNRTNIKISDQSDGQTTDINLPGITAAPADLD
CCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHH
AVCERVDAVADVAGIALCGSLAGGLPADTYVRLLARLNRRGARTLLDTSGAPLTHALAAP
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHCC
REALPTAIKPNRHELELWAGRPLPALQDVVDAARGIHARGVAQVIVSLGEQGALFVTGEG
HHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCC
IWQASLPPVRAASTVGAGDAMVAGVLAGWHAGASTEETVRLSVAFAACKLQRIGPHLPPP
EEECCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCHHEEEEHHHHHHHHHHHCCCCCCH
QQVRERAAAVHMQRVA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655739; 12024217 [H]