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The map label for this gene is aroE [H]

Identifier: 17547496

GI number: 17547496

Start: 2987691

End: 2988611

Strand: Reverse

Name: aroE [H]

Synonym: RSc2777

Alternate gene names: 17547496

Gene position: 2988611-2987691 (Counterclockwise)

Preceding gene: 17547497

Following gene: 17547495

Centisome position: 80.42

GC content: 68.19

Gene sequence:

>921_bases
ATGATATCGTTTGAACAGGCGGCCATTCTCGCGGCCGCCAGCGCCCCGCCAGTCGATCGCTACGGTGTGATCGGCAATCC
GATCTCGCACAGCAAGTCGCCGGCCATCCATGCCGCCTTTGCGCAGCAGACCGGCCAGCTGATGCGCTATGAGCGCATCT
ATGCCGAGCTGATTGCCTTTGACGAGACCGTGTTCTCGTTCATCCGTGAGGGCGGGCGGGGGCTCAATGTGACGGTGCCG
TTCAAGCTCGATGCGTACGCACTGGCGACCTCGCTGTCGCTGCGTGCGGAGTCGGCCGGCGCCGTCAACACCCTCAAGTT
CGACGGCGATGCGATTTTCGGCGACAACACCGATGGCGTCGGCCTGATGCGCGATATCACGCACAACATCGGCAACCCGC
TGGCGGGTGAGCGCGTGCTGCTGCTCGGCGCGGGCGGCGCGGCGCGCGGCATCCTGCTGCCGCTGCTGGAGCACAAGCCG
TCGCGCGTGTTCATCGCCAATCGCACAGCCGATCGCGCCATCGGGCTGGTGCAGCGCTTCGAGGCAGCGGCCAAGCTGCA
CGAGGTCGAGCTGGTGGGCGGCGGCTTCGACGACCTGGCCGTCAGCGACGTCTTCGATGTCGTCATCAACGCGACCGCGG
GCAGCCTGCAGGCCCAGGTGCCGCCCATCGAGCCGACCGTGTTCGGCCCCAACGCGCTGGCCTACGACATGATGTACGGC
TCGCAGCCGACGGTGTTCATGCAGTTCGCCAAGCGGCATGGTGCCCGCGCGTGGGACGGCCTGGGCATGCTGGTGGAGCA
GGCGGCGGAATCGTTCCTGGTCTGGCGCGGCATGCGCCCCGACACCGCCCCCGTGCTACAAGCCATGCGCGAGGGGCTGC
AGGGCGAGGCGGCCGTGGCCGCGCGCGCGCATCAGCGCTGA

Upstream 100 bases:

>100_bases
GCGCCTTCCCGGTCGAGATGCGCAAGCGCGTCGACATCCAGGACGTGGTCGCCACCTTCAAGTTCACCCGCGCCGGCCTG
GAAACCCGCCTGCAGACCCG

Downstream 100 bases:

>100_bases
GCGCCCGCAGCCCGCACCATGATGCGCTGGCTCGGCTACGTGATCGGCTGCTTTGCGGCGGGCGTGGTCGCGCTCAACCT
GTATTTCTTCGCCGCCATCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MISFEQAAILAAASAPPVDRYGVIGNPISHSKSPAIHAAFAQQTGQLMRYERIYAELIAFDETVFSFIREGGRGLNVTVP
FKLDAYALATSLSLRAESAGAVNTLKFDGDAIFGDNTDGVGLMRDITHNIGNPLAGERVLLLGAGGAARGILLPLLEHKP
SRVFIANRTADRAIGLVQRFEAAAKLHEVELVGGGFDDLAVSDVFDVVINATAGSLQAQVPPIEPTVFGPNALAYDMMYG
SQPTVFMQFAKRHGARAWDGLGMLVEQAAESFLVWRGMRPDTAPVLQAMREGLQGEAAVAARAHQR

Sequences:

>Translated_306_residues
MISFEQAAILAAASAPPVDRYGVIGNPISHSKSPAIHAAFAQQTGQLMRYERIYAELIAFDETVFSFIREGGRGLNVTVP
FKLDAYALATSLSLRAESAGAVNTLKFDGDAIFGDNTDGVGLMRDITHNIGNPLAGERVLLLGAGGAARGILLPLLEHKP
SRVFIANRTADRAIGLVQRFEAAAKLHEVELVGGGFDDLAVSDVFDVVINATAGSLQAQVPPIEPTVFGPNALAYDMMYG
SQPTVFMQFAKRHGARAWDGLGMLVEQAAESFLVWRGMRPDTAPVLQAMREGLQGEAAVAARAHQR
>Mature_306_residues
MISFEQAAILAAASAPPVDRYGVIGNPISHSKSPAIHAAFAQQTGQLMRYERIYAELIAFDETVFSFIREGGRGLNVTVP
FKLDAYALATSLSLRAESAGAVNTLKFDGDAIFGDNTDGVGLMRDITHNIGNPLAGERVLLLGAGGAARGILLPLLEHKP
SRVFIANRTADRAIGLVQRFEAAAKLHEVELVGGGFDDLAVSDVFDVVINATAGSLQAQVPPIEPTVFGPNALAYDMMYG
SQPTVFMQFAKRHGARAWDGLGMLVEQAAESFLVWRGMRPDTAPVLQAMREGLQGEAAVAARAHQR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=43.1654676258993, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787983, Length=269, Percent_Identity=27.5092936802974, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=281, Percent_Identity=26.6903914590747, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32672; Mature: 32672

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFEQAAILAAASAPPVDRYGVIGNPISHSKSPAIHAAFAQQTGQLMRYERIYAELIAF
CCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DETVFSFIREGGRGLNVTVPFKLDAYALATSLSLRAESAGAVNTLKFDGDAIFGDNTDGV
HHHHHHHHHCCCCCCEEEECCEECHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCC
GLMRDITHNIGNPLAGERVLLLGAGGAARGILLPLLEHKPSRVFIANRTADRAIGLVQRF
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
EAAAKLHEVELVGGGFDDLAVSDVFDVVINATAGSLQAQVPPIEPTVFGPNALAYDMMYG
HHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCEEEEECCC
SQPTVFMQFAKRHGARAWDGLGMLVEQAAESFLVWRGMRPDTAPVLQAMREGLQGEAAVA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCHHHH
ARAHQR
HHHCCC
>Mature Secondary Structure
MISFEQAAILAAASAPPVDRYGVIGNPISHSKSPAIHAAFAQQTGQLMRYERIYAELIAF
CCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DETVFSFIREGGRGLNVTVPFKLDAYALATSLSLRAESAGAVNTLKFDGDAIFGDNTDGV
HHHHHHHHHCCCCCCEEEECCEECHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCC
GLMRDITHNIGNPLAGERVLLLGAGGAARGILLPLLEHKPSRVFIANRTADRAIGLVQRF
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
EAAAKLHEVELVGGGFDDLAVSDVFDVVINATAGSLQAQVPPIEPTVFGPNALAYDMMYG
HHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEECCCCEEEEECCC
SQPTVFMQFAKRHGARAWDGLGMLVEQAAESFLVWRGMRPDTAPVLQAMREGLQGEAAVA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCHHHH
ARAHQR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA