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The map label for this gene is mtgA

Identifier: 17547495

GI number: 17547495

Start: 2986968

End: 2987672

Strand: Reverse

Name: mtgA

Synonym: RSc2776

Alternate gene names: 17547495

Gene position: 2987672-2986968 (Counterclockwise)

Preceding gene: 17547496

Following gene: 17547494

Centisome position: 80.39

GC content: 65.25

Gene sequence:

>705_bases
ATGATGCGCTGGCTCGGCTACGTGATCGGCTGCTTTGCGGCGGGCGTGGTCGCGCTCAACCTGTATTTCTTCGCCGCCAT
CGCCAGTTGGCAGGTCTTCAATCCCGCCTCGTCGGCGTTCATGCGGGCCGAGCGGATGCGGCTGTGCGGTGCCAATCTCG
TCACCTGCGGGATCGACCATCGCTGGGTGCCGTACGACCAGATCTCGCGCAACCTCAAGCGCGCCGTCATCGCCAGCGAG
GACGCCGATTTCGTCTCGCATTCCGGCTGGGAAGTCGACGCCATGCTCGACGCCTGGGAAAAGAACAAGCGGCGCGGCCA
CGTGGTGGCGGGCGGCTCGACCATCACGCAGCAGCTGGCCAAGAACCTGTTCCTCTCCGGCGAGCGCCACTACCTGCGCA
AGGGCGAGGAGCTCGTTATCACGTGGATGCTGGAGTTCTGGCTCGACAAGGAGCGCATCCTGGAGATCTACTTGAATTCG
GTGGAGTGGGGCGAGGGCGTCTTCGGCGCCGAGGCGGCGGCGCAGCATTACTTCAAACGGCCGGCATCGCAATTGACGGT
GGGCCAGGCCGCGCGACTGGCCGCGGCGCTGCCGGCGCCCAAGTGCTTCGACAAGAAGCGCTACTGCGCCAATGTTCACA
TCAGTTTCACGCGCAAGGCGACGGTCATCGCCAACCGGATGGGCTCGGCGACCCTGCCGGACTGA

Upstream 100 bases:

>100_bases
CGACACCGCCCCCGTGCTACAAGCCATGCGCGAGGGGCTGCAGGGCGAGGCGGCCGTGGCCGCGCGCGCGCATCAGCGCT
GAGCGCCCGCAGCCCGCACC

Downstream 100 bases:

>100_bases
CCCGGCTCAGGCACGCGGGGGCTTCGTAAACCTGCACTCAGTTGCGGTTTCGGAGCGAGGTTGAAGGGGCCTGAAAGGTA
CAACTGTCCAACGCGCCTCA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MMRWLGYVIGCFAAGVVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDHRWVPYDQISRNLKRAVIASE
DADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLAKNLFLSGERHYLRKGEELVITWMLEFWLDKERILEIYLNS
VEWGEGVFGAEAAAQHYFKRPASQLTVGQAARLAAALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLPD

Sequences:

>Translated_234_residues
MMRWLGYVIGCFAAGVVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDHRWVPYDQISRNLKRAVIASE
DADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLAKNLFLSGERHYLRKGEELVITWMLEFWLDKERILEIYLNS
VEWGEGVFGAEAAAQHYFKRPASQLTVGQAARLAAALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLPD
>Mature_234_residues
MMRWLGYVIGCFAAGVVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDHRWVPYDQISRNLKRAVIASE
DADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLAKNLFLSGERHYLRKGEELVITWMLEFWLDKERILEIYLNS
VEWGEGVFGAEAAAQHYFKRPASQLTVGQAARLAAALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLPD

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=142, Percent_Identity=50.7042253521127, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082258, Length=148, Percent_Identity=39.8648648648649, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786343, Length=167, Percent_Identity=32.9341317365269, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_RALSO (Q8XVQ4)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520897.1
- ProteinModelPortal:   Q8XVQ4
- SMR:   Q8XVQ4
- GeneID:   1221623
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2776
- NMPDR:   fig|267608.1.peg.2776
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- ProtClustDB:   PRK00056
- BioCyc:   RSOL267608:RSC2776-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26281; Mature: 26281

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf0488a0)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRWLGYVIGCFAAGVVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEECCCC
RWVPYDQISRNLKRAVIASEDADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLA
CCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHH
KNLFLSGERHYLRKGEELVITWMLEFWLDKERILEIYLNSVEWGEGVFGAEAAAQHYFKR
HHHHCCCCHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PASQLTVGQAARLAAALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLPD
CHHHHHHHHHHHHHHHCCCCHHHCCCHHEEEEEEEECCHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MMRWLGYVIGCFAAGVVALNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCEEEECCCC
RWVPYDQISRNLKRAVIASEDADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLA
CCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHH
KNLFLSGERHYLRKGEELVITWMLEFWLDKERILEIYLNSVEWGEGVFGAEAAAQHYFKR
HHHHCCCCHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
PASQLTVGQAARLAAALPAPKCFDKKRYCANVHISFTRKATVIANRMGSATLPD
CHHHHHHHHHHHHHHHCCCCHHHCCCHHEEEEEEEECCHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852