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The map label for this gene is recG [H]

Identifier: 17547430

GI number: 17547430

Start: 2915533

End: 2917548

Strand: Reverse

Name: recG [H]

Synonym: RSc2711

Alternate gene names: 17547430

Gene position: 2917548-2915533 (Counterclockwise)

Preceding gene: 17547436

Following gene: 17547427

Centisome position: 78.5

GC content: 72.32

Gene sequence:

>2016_bases
GTGCTGCACCTGCCGATGCGCTATGAGGACGAAACCGCGCTGCTGACCATCGCCGAGGCCGTCGCCCGCGCCAATACCGG
CTGGGCCGCGCAGGTGGATGGGGTGGTGACGCGCAACGAAGTGGCGTTCCGGCCCCGCCGGCAACTGGTGGTGCACATCG
CCGACGATTCCGGCGAGCTGGTGCTGCGCTTTCTCAACTTCTACGGCAGCCAGGTCAAGCAGATGGCCGAGGGTGCGCGC
CTGCGCGTGCGCGGCGAGGTGCGCGGCGGCTTCTTCGGCGCGGAGATGGTGCATCCGGCGGTGCGCGCCGTGACGCCGGA
CGAGCCGCTGCCCGACCGCCTGACCCCGGTCTATCCCAGCACCGCCGGCGTGGCGCAGGCGTATCTGCGCAAGGCCATCC
TGAACGCGCTCGGCCGCACGCCGCTGCCCGAGACCCTGCCGGACAGCCTGTTGCGCGGGCCGCTGGCGCCGCTCAAGCTG
ATGGCGCCCGCCGAGGCCGTCCGCCTGCTGCACCAGCCCACGCCCGACGTGGATGAGCACAGCCTGGTCGAACGCACCCA
CCCGGCCTGGCTGCGCATCAAGTTCGACGAACTGCTGGCGCAGCAACTGTCGCTCAAGCGCGCCCAGGCTGCGCGCCGCA
CGCGCAGCGCGCCGGTGCTGCGGGCCGGCGGCGCGGACGGGCTGCTCGCGCGCTTCCTGGCGGCGCTGCCCTTCAAGCTG
ACCGGCGCGCAGGCCCGCGTGTGGGAGGAGATCCGCGCGGACCTCGCCCGGCCGTACCCGATGCAGCGGCTGCTGCAGGG
CGACGTGGGCAGCGGCAAGACCGTCATCGCCGCGCTGGCCGCGTGCCAGGCCATCGACGCCGGCCGGCAGGCCGCGCTGA
TGGCGCCGACCGAACTGCTGGCCGAGCAGCACTACCGCAAGCTGTCGGCCTGGCTCGCGCCGCTGGGCGTGGACATCGTC
TGGCTGGCCGGCAGCCTCAAGCGCAAGCAGAAGGACGAGGCCGCTGCGCGCGTGGCCGCCGGCACCGCGCAACTGGTGAT
CGGCACCCATGCGCTGATCCAGGACACCGTGACTTTCGCCCGCCTGGGGCTGGCCGTGGTGGACGAGCAGCACCGCTTCG
GCGTGGCGCAGCGGCTGGCGCTGCGCGGCAAGGCCGGCGGCACCGACACGCCCGTCGCCGAGACCGCGCAGTTGGTGCCG
CACCAGCTGATGATGTCGGCCACGCCGATCCCGCGCACGCTGGCGATGACGTACTACGCCGACCTCGACGTCTCGGCCAT
CGACGAGCTGCCGCCCGGCCGCACGCCGGTGGTCACGCGCCTGGTCAACGATGCGCGCCGCGACGAGGTGATCGAACGCA
TCCACGCCGCCGCGCGCGAGGGGCGGCAGGTCTACTGGGTCTGCCCCCTGATCGAAGAGAGCGAGGCGTTGCAGCTGCAG
ACTGCCGTCGAGACGTTCGAGACGCTGTCGCAGAGCCTGGCCGGCCTCAAGGTCGGGCTGGTGCACGGGCGCCTGCCGTC
CGCCGACAAGGCCGCGGTGATGAGCGCCTTCGCCGGCGGCGAGCTGCACGTGCTGGTGGCGACCACCGTGATCGAAGTGG
GCGTCGACGTGCCCAACGCCTCGCTGATGGTGATCGAGCACGCCGAGCGCTTCGGGCTGGCGCAGCTCCATCAACTGCGC
GGACGGGTCGGGCGCGGCACGGCCGAATCGGTCTGCATCCTGCTGTACCAGGCGCCCCTGTCGCCGACGGCCAAACAGCG
CTTGCAGACCATGCGCGAGACCACCGACGGCTTCGAGATCGCGCGGCGCGACCTGGATATCCGCGGCCCTGGCGAATTCC
TCGGCGCGCGGCAATCGGGCGAGGCCATGCTGCGCTTTGCCGACCTGAACCACGATGCGTGGATGGTCGAGTTCGCCCAG
GGCGCGGCCGAGCAGATGCTGGCGCGCTTTCCCGACGCGGTGGAGGCGCACCTCAAGCGCTGGCTCGGCGAGCGCGAGCA
CTACCTGCGCGTCTAG

Upstream 100 bases:

>100_bases
GCGCGCGCCCGCGGCGAAGCCCGCGGACAAGCCGGCCGCCAAGACCGCTCGCCCCGCCGACAAGCTGGCCAAGCTCGGCC
TGCGCCGCGACGTCGATCTC

Downstream 100 bases:

>100_bases
CCGGCGGGGCCGCCGGCCTCATGCGCGGCCGTTGCGCCGCAGCTGGACCGGCGGACACGGGACCGAGCCGTACGAGCAGA
ACACGCAGCAGTCGCCGGGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGAR
LRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPSTAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKL
MAPAEAVRLLHQPTPDVDEHSLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL
TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELLAEQHYRKLSAWLAPLGVDIV
WLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDTVTFARLGLAVVDEQHRFGVAQRLALRGKAGGTDTPVAETAQLVP
HQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTPVVTRLVNDARRDEVIERIHAAAREGRQVYWVCPLIEESEALQLQ
TAVETFETLSQSLAGLKVGLVHGRLPSADKAAVMSAFAGGELHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLR
GRVGRGTAESVCILLYQAPLSPTAKQRLQTMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNHDAWMVEFAQ
GAAEQMLARFPDAVEAHLKRWLGEREHYLRV

Sequences:

>Translated_671_residues
MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGAR
LRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPSTAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKL
MAPAEAVRLLHQPTPDVDEHSLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL
TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELLAEQHYRKLSAWLAPLGVDIV
WLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDTVTFARLGLAVVDEQHRFGVAQRLALRGKAGGTDTPVAETAQLVP
HQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTPVVTRLVNDARRDEVIERIHAAAREGRQVYWVCPLIEESEALQLQ
TAVETFETLSQSLAGLKVGLVHGRLPSADKAAVMSAFAGGELHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLR
GRVGRGTAESVCILLYQAPLSPTAKQRLQTMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNHDAWMVEFAQ
GAAEQMLARFPDAVEAHLKRWLGEREHYLRV
>Mature_671_residues
MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGELVLRFLNFYGSQVKQMAEGAR
LRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPSTAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKL
MAPAEAVRLLHQPTPDVDEHSLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL
TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELLAEQHYRKLSAWLAPLGVDIV
WLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDTVTFARLGLAVVDEQHRFGVAQRLALRGKAGGTDTPVAETAQLVP
HQLMMSATPIPRTLAMTYYADLDVSAIDELPPGRTPVVTRLVNDARRDEVIERIHAAAREGRQVYWVCPLIEESEALQLQ
TAVETFETLSQSLAGLKVGLVHGRLPSADKAAVMSAFAGGELHVLVATTVIEVGVDVPNASLMVIEHAERFGLAQLHQLR
GRVGRGTAESVCILLYQAPLSPTAKQRLQTMRETTDGFEIARRDLDIRGPGEFLGARQSGEAMLRFADLNHDAWMVEFAQ
GAAEQMLARFPDAVEAHLKRWLGEREHYLRV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=679, Percent_Identity=51.2518409425626, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1787357, Length=394, Percent_Identity=37.3096446700508, Blast_Score=233, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 73298; Mature: 73298

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCEEEEEEEECCCHHH
VLRFLNFYGSQVKQMAEGARLRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPS
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
TAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKLMAPAEAVRLLHQPTPDVDEH
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCCHH
SLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCEE
TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELL
CCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHH
AEQHYRKLSAWLAPLGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDTVTFA
HHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLGLAVVDEQHRFGVAQRLALRGKAGGTDTPVAETAQLVPHQLMMSATPIPRTLAMTYYA
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEE
DLDVSAIDELPPGRTPVVTRLVNDARRDEVIERIHAAAREGRQVYWVCPLIEESEALQLQ
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
TAVETFETLSQSLAGLKVGLVHGRLPSADKAAVMSAFAGGELHVLVATTVIEVGVDVPNA
HHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
SLMVIEHAERFGLAQLHQLRGRVGRGTAESVCILLYQAPLSPTAKQRLQTMRETTDGFEI
CEEEEECHHHCCHHHHHHHHHHCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCHHHH
ARRDLDIRGPGEFLGARQSGEAMLRFADLNHDAWMVEFAQGAAEQMLARFPDAVEAHLKR
HHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLGEREHYLRV
HHCCCHHHCCC
>Mature Secondary Structure
MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCEEEEEEEECCCHHH
VLRFLNFYGSQVKQMAEGARLRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPS
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
TAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKLMAPAEAVRLLHQPTPDVDEH
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCCHH
SLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCEE
TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELL
CCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHH
AEQHYRKLSAWLAPLGVDIVWLAGSLKRKQKDEAAARVAAGTAQLVIGTHALIQDTVTFA
HHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLGLAVVDEQHRFGVAQRLALRGKAGGTDTPVAETAQLVPHQLMMSATPIPRTLAMTYYA
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEE
DLDVSAIDELPPGRTPVVTRLVNDARRDEVIERIHAAAREGRQVYWVCPLIEESEALQLQ
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
TAVETFETLSQSLAGLKVGLVHGRLPSADKAAVMSAFAGGELHVLVATTVIEVGVDVPNA
HHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCC
SLMVIEHAERFGLAQLHQLRGRVGRGTAESVCILLYQAPLSPTAKQRLQTMRETTDGFEI
CEEEEECHHHCCHHHHHHHHHHCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHCCCHHHH
ARRDLDIRGPGEFLGARQSGEAMLRFADLNHDAWMVEFAQGAAEQMLARFPDAVEAHLKR
HHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLGEREHYLRV
HHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]