Click here to switch to the map view.

The map label for this gene is ttdR [H]

Identifier: 17547427

GI number: 17547427

Start: 2911930

End: 2913054

Strand: Reverse

Name: ttdR [H]

Synonym: RSc2708

Alternate gene names: 17547427

Gene position: 2913054-2911930 (Counterclockwise)

Preceding gene: 17547430

Following gene: 17547426

Centisome position: 78.38

GC content: 68.62

Gene sequence:

>1125_bases
ATGGTCGAAATGGTCGATCTCGACGATCTGCGCATGTTCCGGGCGCTCGGCGTCTCGCGCTCGCTGGCGGCGGCGGCCCG
GCTGCTGGACGTCACGCCACCGGCGCTGACTGTCCGCATGCGGCGGCTGGAGGCGCGGCTCGGGGTGTCGCTCGTGGTGC
GCGAGCCGCGCGGCGTGTCGTTCACCGAGGAAGGCCAGCGGCTTCTGCGGGAAGCGACCGCGCTGCTGGATCGGCTGGAG
TCGCTGCCGCAGCAGGTCTCGGGCCAGGCGGCTGGGGTGAGCGGCCATCTGCGCATCGTCGCGCCGTTCGGGTTCGGCCG
GCGCTACATCGCCCCGATCGTCCGCGATCTGCACCGGGACGCGCCGAAGCTGGCCATCATGCTGCATCTGTCGGACAACC
CGCTGGCCGAGATGTCCGGGGCGGACATCGTCATCCATATCGGCGAGGCCCGGGATTCTTCGTGGGTCGGGCATCCGCTG
GCGCCCAACGAGCGCGTGCTGTGCGCCAGCCCGGCCTGCCTCGCCGGGCTGCCGCCGATCACCCATCCGGCCGAGCTCGC
CCATCTGCCCTGCCTGTGCCTGCGCGAGAACGACGAGGACGTGACGCGCTGGCGCTTTACCGACACCACTGCCGACAGCG
GCCGCGCGAGGCAGGTGGTCAACGTCAGGGTGTCCGGTGCCCTGTCGTCGAACGACGGGACTGTGATCAGCGACTGGGCC
GCCGACGGGCTGGGCGTGATGGTGCGCTCGGAATGGGAGGCGGCGCCGCTGCTGTCGGCGGGCACGCTCGTGCGCCTGCT
GCCGGGCTGGGCGCTGAAGCCCGCGCCGGTGATGGCGCTGGTGCCCACGCGCAAGGGGGTCTCGCCCAGTGACCTCCCCC
CGAAATATTGGACACGCCAGAACTGGAGAAAACCGGCGACACTGCCCTTGAAGGAGGGAGTTCGCCATGAAGAAGTCGAA
GTTCACGGAAGAGCAGATTGCGTTCGCGCTGCATCAGGCCGAGACAGGTGTCTCGGTCGAAGAGGTATGCCGCAAGATTG
GCATCTCGCAAGCGACGTTTTACGCGTGGAAGAAGAAGTACGGCGGTATTGGCGTGAGCGAGCTACGGCGGTTGCGTCAA
CTTGA

Upstream 100 bases:

>100_bases
TCGGGAAGCCGGGCAGCGCGGCCCGGAATACGCAGCACTATAGAAACGCCGGGTGTTCTTGTGTTTAATGGGAAATCAAG
TTCCCATTCATCTGGATTTA

Downstream 100 bases:

>100_bases
AGAGGAGAACGCCAAGCTGCGGCGCTTGGTGGCCGACTTGAGCCTGGACAAGGTCATGCTGCAGGATGTTCTGAGAAAAA
AGCTCTAAGGCCGGCGCAGC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MVEMVDLDDLRMFRALGVSRSLAAAARLLDVTPPALTVRMRRLEARLGVSLVVREPRGVSFTEEGQRLLREATALLDRLE
SLPQQVSGQAAGVSGHLRIVAPFGFGRRYIAPIVRDLHRDAPKLAIMLHLSDNPLAEMSGADIVIHIGEARDSSWVGHPL
APNERVLCASPACLAGLPPITHPAELAHLPCLCLRENDEDVTRWRFTDTTADSGRARQVVNVRVSGALSSNDGTVISDWA
ADGLGVMVRSEWEAAPLLSAGTLVRLLPGWALKPAPVMALVPTRKGVSPSDLPPKYWTRQNWRKPATLPLKEGVRHEEVE
VHGRADCVRAASGRDRCLGRRGMPQDWHLASDVLRVEEEVRRYWRERATAVAST

Sequences:

>Translated_374_residues
MVEMVDLDDLRMFRALGVSRSLAAAARLLDVTPPALTVRMRRLEARLGVSLVVREPRGVSFTEEGQRLLREATALLDRLE
SLPQQVSGQAAGVSGHLRIVAPFGFGRRYIAPIVRDLHRDAPKLAIMLHLSDNPLAEMSGADIVIHIGEARDSSWVGHPL
APNERVLCASPACLAGLPPITHPAELAHLPCLCLRENDEDVTRWRFTDTTADSGRARQVVNVRVSGALSSNDGTVISDWA
ADGLGVMVRSEWEAAPLLSAGTLVRLLPGWALKPAPVMALVPTRKGVSPSDLPPKYWTRQNWRKPATLPLKEGVRHEEVE
VHGRADCVRAASGRDRCLGRRGMPQDWHLASDVLRVEEEVRRYWRERATAVAST
>Mature_374_residues
MVEMVDLDDLRMFRALGVSRSLAAAARLLDVTPPALTVRMRRLEARLGVSLVVREPRGVSFTEEGQRLLREATALLDRLE
SLPQQVSGQAAGVSGHLRIVAPFGFGRRYIAPIVRDLHRDAPKLAIMLHLSDNPLAEMSGADIVIHIGEARDSSWVGHPL
APNERVLCASPACLAGLPPITHPAELAHLPCLCLRENDEDVTRWRFTDTTADSGRARQVVNVRVSGALSSNDGTVISDWA
ADGLGVMVRSEWEAAPLLSAGTLVRLLPGWALKPAPVMALVPTRKGVSPSDLPPKYWTRQNWRKPATLPLKEGVRHEEVE
VHGRADCVRAASGRDRCLGRRGMPQDWHLASDVLRVEEEVRRYWRERATAVAST

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=264, Percent_Identity=35.2272727272727, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87081978, Length=283, Percent_Identity=32.5088339222615, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=24.7349823321555, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=23.7931034482759, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788706, Length=204, Percent_Identity=25.9803921568627, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=264, Percent_Identity=24.2424242424242, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 41111; Mature: 41111

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEMVDLDDLRMFRALGVSRSLAAAARLLDVTPPALTVRMRRLEARLGVSLVVREPRGVS
CCEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCC
FTEEGQRLLREATALLDRLESLPQQVSGQAAGVSGHLRIVAPFGFGRRYIAPIVRDLHRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
APKLAIMLHLSDNPLAEMSGADIVIHIGEARDSSWVGHPLAPNERVLCASPACLAGLPPI
CCEEEEEEEECCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCC
THPAELAHLPCLCLRENDEDVTRWRFTDTTADSGRARQVVNVRVSGALSSNDGTVISDWA
CCCHHHHHCCEEEECCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCEEECCC
ADGLGVMVRSEWEAAPLLSAGTLVRLLPGWALKPAPVMALVPTRKGVSPSDLPPKYWTRQ
CCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCC
NWRKPATLPLKEGVRHEEVEVHGRADCVRAASGRDRCLGRRGMPQDWHLASDVLRVEEEV
CCCCCCCCCHHHCCCCCEEEECCCHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
RRYWRERATAVAST
HHHHHHHHHHHCCC
>Mature Secondary Structure
MVEMVDLDDLRMFRALGVSRSLAAAARLLDVTPPALTVRMRRLEARLGVSLVVREPRGVS
CCEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCC
FTEEGQRLLREATALLDRLESLPQQVSGQAAGVSGHLRIVAPFGFGRRYIAPIVRDLHRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
APKLAIMLHLSDNPLAEMSGADIVIHIGEARDSSWVGHPLAPNERVLCASPACLAGLPPI
CCEEEEEEEECCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHCCCCCC
THPAELAHLPCLCLRENDEDVTRWRFTDTTADSGRARQVVNVRVSGALSSNDGTVISDWA
CCCHHHHHCCEEEECCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCEEECCC
ADGLGVMVRSEWEAAPLLSAGTLVRLLPGWALKPAPVMALVPTRKGVSPSDLPPKYWTRQ
CCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCC
NWRKPATLPLKEGVRHEEVEVHGRADCVRAASGRDRCLGRRGMPQDWHLASDVLRVEEEV
CCCCCCCCCHHHCCCCCEEEECCCHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
RRYWRERATAVAST
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]