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The map label for this gene is btuE [C]

Identifier: 17547393

GI number: 17547393

Start: 2882600

End: 2883097

Strand: Reverse

Name: btuE [C]

Synonym: RSc2674

Alternate gene names: 17547393

Gene position: 2883097-2882600 (Counterclockwise)

Preceding gene: 17547394

Following gene: 17547382

Centisome position: 77.58

GC content: 63.65

Gene sequence:

>498_bases
ATGAGCGACATCTACGCGTTCGAGGCGGATTCACTGGCAGGCCAGCGCGTGCCGCTGTCGCAGTATCGCGGCAAGGTCCT
GCTGATCGTCAACACGGCGAGCCAGTGCGGGTTCACGCCGCAATACGCCGGCCTGGAAGCGGTGTACAAGCGGCTGAACG
AAAAGGGGCTGGAGGTCCTCGGCTTTCCGTGCAACCAGTTCGGCAAGCAGGAGCCGGGCGGGGCGGAGGAGATCGGCGCG
TTCTGCGAGAAGAACTACGGGGTATCGTTCCCCATGTTCGGCAAGATCGAGGTGAACGGGTCGAACGCGCATCCGCTGTA
CAAGTGGCTGACCTCGGAGAAGCCCGGCGTGCTGGGCACGGAAGCCATCAAGTGGAACTTCACCAAGTTTCTGCTGCGCC
GCGACGGCACGGTCTACAAGCGCTACGCGCCGCTGACCAAGCCCGAGGAGATGCTCGGCGATATCGAGACGCTGCTGGCG
GAGCCGGATCCGCTTTGA

Upstream 100 bases:

>100_bases
ACTGAGACTGCGCTGACGTGACGGCCGCCATGCATTGGCGGCCGATTACAATGGGTCTTGTGGGCGGTTCGTTTCTTTCA
CCGAATACCGGAGGATGACC

Downstream 100 bases:

>100_bases
TCGGCGCGCGCCGGACCTAGTCCGTCGAACCCTTCACCTTGCGCATGAAGTCCGCCAGCGAGCGCTCGGCGGATTCAGCG
AAATGCCGCGCCAGGATGTC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSDIYAFEADSLAGQRVPLSQYRGKVLLIVNTASQCGFTPQYAGLEAVYKRLNEKGLEVLGFPCNQFGKQEPGGAEEIGA
FCEKNYGVSFPMFGKIEVNGSNAHPLYKWLTSEKPGVLGTEAIKWNFTKFLLRRDGTVYKRYAPLTKPEEMLGDIETLLA
EPDPL

Sequences:

>Translated_165_residues
MSDIYAFEADSLAGQRVPLSQYRGKVLLIVNTASQCGFTPQYAGLEAVYKRLNEKGLEVLGFPCNQFGKQEPGGAEEIGA
FCEKNYGVSFPMFGKIEVNGSNAHPLYKWLTSEKPGVLGTEAIKWNFTKFLLRRDGTVYKRYAPLTKPEEMLGDIETLLA
EPDPL
>Mature_164_residues
SDIYAFEADSLAGQRVPLSQYRGKVLLIVNTASQCGFTPQYAGLEAVYKRLNEKGLEVLGFPCNQFGKQEPGGAEEIGAF
CEKNYGVSFPMFGKIEVNGSNAHPLYKWLTSEKPGVLGTEAIKWNFTKFLLRRDGTVYKRYAPLTKPEEMLGDIETLLAE
PDPL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=148, Percent_Identity=50, Blast_Score=140, Evalue=4e-34,
Organism=Homo sapiens, GI90903240, Length=148, Percent_Identity=50, Blast_Score=140, Evalue=4e-34,
Organism=Homo sapiens, GI15618997, Length=158, Percent_Identity=44.3037974683544, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI192455698, Length=162, Percent_Identity=38.2716049382716, Blast_Score=121, Evalue=3e-28,
Organism=Homo sapiens, GI90903238, Length=133, Percent_Identity=50.3759398496241, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI41406084, Length=187, Percent_Identity=39.572192513369, Blast_Score=101, Evalue=2e-22,
Organism=Homo sapiens, GI4557629, Length=183, Percent_Identity=37.1584699453552, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=36.4640883977901, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI32967607, Length=179, Percent_Identity=33.5195530726257, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI33186887, Length=154, Percent_Identity=37.012987012987, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI41406082, Length=79, Percent_Identity=51.8987341772152, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788003, Length=159, Percent_Identity=45.2830188679245, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=163, Percent_Identity=50.3067484662577, Blast_Score=156, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=47.5308641975309, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=41.25, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=40.4907975460123, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=34.6153846153846, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=32.967032967033, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71993573, Length=97, Percent_Identity=39.1752577319588, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=41.3333333333333, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=55.9006211180124, Blast_Score=193, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=51.875, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=162, Percent_Identity=44.4444444444444, Blast_Score=153, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=43.75, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=43.75, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=43.75, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=40.8805031446541, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18333; Mature: 18202

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIYAFEADSLAGQRVPLSQYRGKVLLIVNTASQCGFTPQYAGLEAVYKRLNEKGLEVL
CCCCEEECCCCCCCCCCCHHHHCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGGAEEIGAFCEKNYGVSFPMFGKIEVNGSNAHPLYKWLTSEKPGVLGT
ECCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCC
EAIKWNFTKFLLRRDGTVYKRYAPLTKPEEMLGDIETLLAEPDPL
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDIYAFEADSLAGQRVPLSQYRGKVLLIVNTASQCGFTPQYAGLEAVYKRLNEKGLEVL
CCCEEECCCCCCCCCCCHHHHCCEEEEEEECHHHCCCCCCCCCHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGGAEEIGAFCEKNYGVSFPMFGKIEVNGSNAHPLYKWLTSEKPGVLGT
ECCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCC
EAIKWNFTKFLLRRDGTVYKRYAPLTKPEEMLGDIETLLAEPDPL
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]