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The map label for this gene is argF [H]

Identifier: 17547273

GI number: 17547273

Start: 2763052

End: 2763978

Strand: Reverse

Name: argF [H]

Synonym: RSc2554

Alternate gene names: 17547273

Gene position: 2763978-2763052 (Counterclockwise)

Preceding gene: 17547275

Following gene: 17547270

Centisome position: 74.37

GC content: 63.21

Gene sequence:

>927_bases
ATGAACCCACCAAGCAAGATCAAGCATTACCTGCAGTTCAAGGACTTTTCCCTGGAAGAGTACGCGTACCTGCTGGACCG
CTCCAGGATCCTCAAGGCCAAGTTCAAGAACTACGAGACGTGGCACCCGCTGCATGACCGCACGCTGGCCATGATCTTCG
AGAAGAATTCCACGCGCACGCGTCTGTCGTTCGAAGCCGGCATCCACCAGCTCGGCGGCCACGCCGTCTTCCTCAACACG
CGCGACTCGCAACTGGGCCGCGGCGAGCCGATCGAGGACGCGGCGCAGGTCATCTCCCGCATGACCGACATCATCATGAT
CCGCACCTTCGGGCAGGAGATCATCGAGCGCTTTGCCACCCACTCGCGCGTGCCGGTCATCAACGGGCTGACCAACGAAT
ACCATCCGTGCCAGGTGCTGGCCGACATCTTTACCTTCATCGAGCACCGTGGCCCGATCCAGGGCAAGACCGTCACCTGG
GTCGGCGACGCCAACAACATGGCGTACACCTGGATCCAGGCGGCCGAGATCCTCGGCTTCCGCTTCCATTTCTCCGCGCC
CAAGGGCTACCAGCTCGATCCGGTCATGGTGGCCGACTCCAGCCGCCCGTTCGTGCACGTGTTCGAGAACCCGCTCGAAG
CCTGCGAAGGCGCCCACCTGGTGACCACCGACGTGTGGACCAGCATGGGCTACGAGGCCGAGAACGAAGCGCGCAAGAAG
GCCTTCGGCGACTGGATGGTCACCGAAGCGATGATGCAGCGCGCCCAGCCTGACGCGCTGTTCATGCACTGCCTGCCCGC
GCACCGCGGCGAGGAAGTCGAAGCGGCCGTCATCGACGGCAAGCAGAGCGTCGTGTGGGACGAGGCGGAAAACCGCCTGC
ACGTGCAGAAGGCGCTGATGGAATACCTGCTCTGCGGCCGGTACTAA

Upstream 100 bases:

>100_bases
ATCCCGTATGATGCCTTGAATCGACATCAGGCAAGGCGGCTAGGGCGGCGCGGATGGGTCATACCACGGAGCGCCGACTG
CGGGCCGCCTTCGTTGTTTT

Downstream 100 bases:

>100_bases
GACAGCCCTGGTGACCTGGCAGTGACTCGAACCGAGTCTGAAGCCACAAAAAAAGGCCGCTCCGATTGATGTCGGAGCGG
CCTTTTTCGTTTTGAAGCGT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNPPSKIKHYLQFKDFSLEEYAYLLDRSRILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFATHSRVPVINGLTNEYHPCQVLADIFTFIEHRGPIQGKTVTW
VGDANNMAYTWIQAAEILGFRFHFSAPKGYQLDPVMVADSSRPFVHVFENPLEACEGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY

Sequences:

>Translated_308_residues
MNPPSKIKHYLQFKDFSLEEYAYLLDRSRILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFATHSRVPVINGLTNEYHPCQVLADIFTFIEHRGPIQGKTVTW
VGDANNMAYTWIQAAEILGFRFHFSAPKGYQLDPVMVADSSRPFVHVFENPLEACEGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY
>Mature_308_residues
MNPPSKIKHYLQFKDFSLEEYAYLLDRSRILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFATHSRVPVINGLTNEYHPCQVLADIFTFIEHRGPIQGKTVTW
VGDANNMAYTWIQAAEILGFRFHFSAPKGYQLDPVMVADSSRPFVHVFENPLEACEGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=307, Percent_Identity=38.7622149837134, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI18105007, Length=311, Percent_Identity=27.9742765273312, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=37.5384615384615, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36.9230769230769, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI2367364, Length=200, Percent_Identity=35, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994908, Length=323, Percent_Identity=25.6965944272446, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=294, Percent_Identity=27.5510204081633, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=325, Percent_Identity=32.6153846153846, Blast_Score=183, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322331, Length=163, Percent_Identity=31.2883435582822, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=27.831715210356, Blast_Score=111, Evalue=6e-25,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35339; Mature: 35339

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPSKIKHYLQFKDFSLEEYAYLLDRSRILKAKFKNYETWHPLHDRTLAMIFEKNSTRT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCE
RLSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAT
EEEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRVPVINGLTNEYHPCQVLADIFTFIEHRGPIQGKTVTWVGDANNMAYTWIQAAEILGF
CCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEHHHHHHHHHEE
RFHFSAPKGYQLDPVMVADSSRPFVHVFENPLEACEGAHLVTTDVWTSMGYEAENEARKK
EEEECCCCCCCCCCEEEECCCCCEEEECCCHHHHHCCCEEEEHHHHHHCCCCCHHHHHHH
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALM
HHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
EYLLCGRY
HHHHHCCC
>Mature Secondary Structure
MNPPSKIKHYLQFKDFSLEEYAYLLDRSRILKAKFKNYETWHPLHDRTLAMIFEKNSTRT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCE
RLSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAT
EEEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRVPVINGLTNEYHPCQVLADIFTFIEHRGPIQGKTVTWVGDANNMAYTWIQAAEILGF
CCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEHHHHHHHHHEE
RFHFSAPKGYQLDPVMVADSSRPFVHVFENPLEACEGAHLVTTDVWTSMGYEAENEARKK
EEEECCCCCCCCCCEEEECCCCCEEEECCCHHHHHCCCEEEEHHHHHHCCCCCHHHHHHH
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALM
HHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
EYLLCGRY
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA