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The map label for this gene is opuBB [H]

Identifier: 17547235

GI number: 17547235

Start: 2722559

End: 2724121

Strand: Direct

Name: opuBB [H]

Synonym: RSc2516

Alternate gene names: 17547235

Gene position: 2722559-2724121 (Clockwise)

Preceding gene: 17547234

Following gene: 17547236

Centisome position: 73.26

GC content: 73.7

Gene sequence:

>1563_bases
TTGGATACACGGCGACTGATCCGCAATCCGTTCCTGCGGCGCCTCCTGGCATGGATGGCGCTCGGATGGCTGGCGTGCGG
CACGCTGGCCTGGGCGGAAGCGCCGCTGCGGATCGGCTCCAAGCGCTTCACCGAAGCCTACGTCCTGGGCGAGGTGCTGA
CGCAGGCCGCCGCCCCGCATGGCCCCGCCGAACACGTTCCGGGACTCGGCAACACGGCGATCGTCTTTGCCGCGCTCAGG
AGCGGCAGCATCGACCTCTATCCCGACTACCTCGGCACCATCGCCGCCGAGATCCTGCACCTGCCGCCCGCGCAGGCGGC
CAATCCGGACCAGGCCGCGCTGCTGGCCGACGTCAACCGCGCGCTGGCGCCGCTGGGCCTGGGCGCGGGCGTGCCGCTCG
GCTTCGAGGACACCTATGCGCTCGCCATGCGCGAGGCCGACGCCGAACGCGAGGGCATCCGCACGCTGGCCGACCTGGCG
GCACACCCCGCGCTGCGGCTGGGGCTGTCGCACGAATTCCTCGGCCGCGCGGACGGCTGGCCGGCGCTCGTCCGGCGCTA
CGGCCTGCCGCAGCAGCCGACCGGCCTCGACCACGGCGTCGCCTACGACGCGCTGCGCGCCGGCCAGACCGACGCGATCG
ACATCTATTCCACCGATGCCCGGATCCGCCGCGAACACCTGCGCGTGCTGGAGGACAGCGCGCACGTCTTCCCCCGCTAC
GATGCCGTGGTGCTCTACCGGCTCGACGTGCCGGCGCGGCACGCGGCGCAATGGCGGGCGATCATGGCGCTCGCCGGCCG
CATCCATCGCGACGAGATGGTGGCGATGAACGCCGCGGTCGAACTGGAGGGCCAGCCCTTCGCGCGGGTCGCGGCGCGGT
TCCTGGCCGGCCACGGCATGCCTGCGGCGCGGGCGGAGGCACCCACGCGTGCCTTCCTCGCGCAGCTGGGCGACGGCCTG
TGGCGCCTCACGCGGCGGCATCTGGCGCTGGTGGCGATCTCGACCGGGGCGGCCGCGCTGATCGGCGTGCCGCTCGGGCT
GCTGGCGGCGCGGCGGCGGATCCAGCAGCCGGTGCTGGCCATCGTGGGCGTGCTGCAGACGATTCCGTCGCTGGCCCTGC
TGGCGATGCTGATTCCGCTGGTCGGGTCGATCGGCGTGGTGCCGGCACTGATCGCGCTCACGCTGTATGCGCTGCTGCCG
ATCGTGCGCAACACCATCGTCGGGCTGGAACAGGTGCCCGACGGCCTGCGCGATGCGGCGCTGGCGCTGGGCTTCACGCC
GGCGCAGCGCACGCGCGTGGTCGACCTGCCGCTGGCGCTGCCGGTCATCCTCGCGGGCATCAAGACCGCCGCCGTGATCA
GCGTCGGCACCGCGACCATCGCGGCCTTCATCGGCGCGGGCGGATATGGCGAGCGCATTGCCACCGGCCTGGCCCTCAAC
GACAGCGCGATCCTGCTGGCAGGCGCGATCCCGGCCGCCGTGCTGGCGCTGCTGGTGCAGGGCGCCTTCGAAGCCGCCGA
AGGATGGCTGCGGCGGCGCCGGCAGCCGCCCCCGCCGCGCTAG

Upstream 100 bases:

>100_bases
CGCGCATCACGCCCGAAGTCATCGACCTGGCGCAGACCGGCGACCAGATCGTCTCGCGCGAAGAACCCGGCGACTGGGGC
CTGACCGACCTCCACGAACT

Downstream 100 bases:

>100_bases
CAAGCGCGCCGGGCCGCCTTCCATTACCATGCGCGGTTGTCCTGCCGACCGCGTTGACCCGCCCCGCCTGCCCATGACCA
CGCTTTCGTTTTCCACCGCC

Product: lipoprotein transmembrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MDTRRLIRNPFLRRLLAWMALGWLACGTLAWAEAPLRIGSKRFTEAYVLGEVLTQAAAPHGPAEHVPGLGNTAIVFAALR
SGSIDLYPDYLGTIAAEILHLPPAQAANPDQAALLADVNRALAPLGLGAGVPLGFEDTYALAMREADAEREGIRTLADLA
AHPALRLGLSHEFLGRADGWPALVRRYGLPQQPTGLDHGVAYDALRAGQTDAIDIYSTDARIRREHLRVLEDSAHVFPRY
DAVVLYRLDVPARHAAQWRAIMALAGRIHRDEMVAMNAAVELEGQPFARVAARFLAGHGMPAARAEAPTRAFLAQLGDGL
WRLTRRHLALVAISTGAAALIGVPLGLLAARRRIQQPVLAIVGVLQTIPSLALLAMLIPLVGSIGVVPALIALTLYALLP
IVRNTIVGLEQVPDGLRDAALALGFTPAQRTRVVDLPLALPVILAGIKTAAVISVGTATIAAFIGAGGYGERIATGLALN
DSAILLAGAIPAAVLALLVQGAFEAAEGWLRRRRQPPPPR

Sequences:

>Translated_520_residues
MDTRRLIRNPFLRRLLAWMALGWLACGTLAWAEAPLRIGSKRFTEAYVLGEVLTQAAAPHGPAEHVPGLGNTAIVFAALR
SGSIDLYPDYLGTIAAEILHLPPAQAANPDQAALLADVNRALAPLGLGAGVPLGFEDTYALAMREADAEREGIRTLADLA
AHPALRLGLSHEFLGRADGWPALVRRYGLPQQPTGLDHGVAYDALRAGQTDAIDIYSTDARIRREHLRVLEDSAHVFPRY
DAVVLYRLDVPARHAAQWRAIMALAGRIHRDEMVAMNAAVELEGQPFARVAARFLAGHGMPAARAEAPTRAFLAQLGDGL
WRLTRRHLALVAISTGAAALIGVPLGLLAARRRIQQPVLAIVGVLQTIPSLALLAMLIPLVGSIGVVPALIALTLYALLP
IVRNTIVGLEQVPDGLRDAALALGFTPAQRTRVVDLPLALPVILAGIKTAAVISVGTATIAAFIGAGGYGERIATGLALN
DSAILLAGAIPAAVLALLVQGAFEAAEGWLRRRRQPPPPR
>Mature_520_residues
MDTRRLIRNPFLRRLLAWMALGWLACGTLAWAEAPLRIGSKRFTEAYVLGEVLTQAAAPHGPAEHVPGLGNTAIVFAALR
SGSIDLYPDYLGTIAAEILHLPPAQAANPDQAALLADVNRALAPLGLGAGVPLGFEDTYALAMREADAEREGIRTLADLA
AHPALRLGLSHEFLGRADGWPALVRRYGLPQQPTGLDHGVAYDALRAGQTDAIDIYSTDARIRREHLRVLEDSAHVFPRY
DAVVLYRLDVPARHAAQWRAIMALAGRIHRDEMVAMNAAVELEGQPFARVAARFLAGHGMPAARAEAPTRAFLAQLGDGL
WRLTRRHLALVAISTGAAALIGVPLGLLAARRRIQQPVLAIVGVLQTIPSLALLAMLIPLVGSIGVVPALIALTLYALLP
IVRNTIVGLEQVPDGLRDAALALGFTPAQRTRVVDLPLALPVILAGIKTAAVISVGTATIAAFIGAGGYGERIATGLALN
DSAILLAGAIPAAVLALLVQGAFEAAEGWLRRRRQPPPPR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=206, Percent_Identity=40.2912621359223, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788449, Length=181, Percent_Identity=39.2265193370166, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789033, Length=162, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788452, Length=289, Percent_Identity=29.0657439446367, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55150; Mature: 55150

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRRLIRNPFLRRLLAWMALGWLACGTLAWAEAPLRIGSKRFTEAYVLGEVLTQAAAPH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHCCCC
GPAEHVPGLGNTAIVFAALRSGSIDLYPDYLGTIAAEILHLPPAQAANPDQAALLADVNR
CCHHHCCCCCCHHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALAPLGLGAGVPLGFEDTYALAMREADAEREGIRTLADLAAHPALRLGLSHEFLGRADGW
HHHHCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCC
PALVRRYGLPQQPTGLDHGVAYDALRAGQTDAIDIYSTDARIRREHLRVLEDSAHVFPRY
HHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCC
DAVVLYRLDVPARHAAQWRAIMALAGRIHRDEMVAMNAAVELEGQPFARVAARFLAGHGM
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCC
PAARAEAPTRAFLAQLGDGLWRLTRRHLALVAISTGAAALIGVPLGLLAARRRIQQPVLA
CCHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IVGVLQTIPSLALLAMLIPLVGSIGVVPALIALTLYALLPIVRNTIVGLEQVPDGLRDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LALGFTPAQRTRVVDLPLALPVILAGIKTAAVISVGTATIAAFIGAGGYGERIATGLALN
HHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEC
DSAILLAGAIPAAVLALLVQGAFEAAEGWLRRRRQPPPPR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTRRLIRNPFLRRLLAWMALGWLACGTLAWAEAPLRIGSKRFTEAYVLGEVLTQAAAPH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHCCCC
GPAEHVPGLGNTAIVFAALRSGSIDLYPDYLGTIAAEILHLPPAQAANPDQAALLADVNR
CCHHHCCCCCCHHHHHHHHHCCCCEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALAPLGLGAGVPLGFEDTYALAMREADAEREGIRTLADLAAHPALRLGLSHEFLGRADGW
HHHHCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCC
PALVRRYGLPQQPTGLDHGVAYDALRAGQTDAIDIYSTDARIRREHLRVLEDSAHVFPRY
HHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCC
DAVVLYRLDVPARHAAQWRAIMALAGRIHRDEMVAMNAAVELEGQPFARVAARFLAGHGM
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCC
PAARAEAPTRAFLAQLGDGLWRLTRRHLALVAISTGAAALIGVPLGLLAARRRIQQPVLA
CCHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IVGVLQTIPSLALLAMLIPLVGSIGVVPALIALTLYALLPIVRNTIVGLEQVPDGLRDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LALGFTPAQRTRVVDLPLALPVILAGIKTAAVISVGTATIAAFIGAGGYGERIATGLALN
HHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEC
DSAILLAGAIPAAVLALLVQGAFEAAEGWLRRRRQPPPPR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]