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The map label for this gene is vsrC [H]

Identifier: 17547174

GI number: 17547174

Start: 2661423

End: 2662088

Strand: Direct

Name: vsrC [H]

Synonym: RSc2455

Alternate gene names: 17547174

Gene position: 2661423-2662088 (Clockwise)

Preceding gene: 17547166

Following gene: 17547176

Centisome position: 71.61

GC content: 66.67

Gene sequence:

>666_bases
ATGACGAGCTCGCTGCGTAGCCTGCTGGTGGTCGATGACCACCCTCTCGCCTTATCTGGCACGACCACTTTTCTTGCGCA
AGCCCTGCCTGAAATCCAAGTCCATGCGGCCATCGGCCGGCGTCAGGCCCTGGCGCTGATCGACGAGGGCATCCGCCCGG
ACGTGGTCCTGCTGGATGTCTGGCTGTCCGACTGCACGGGTTTCGACGCGATGCGCGAACTGCGCGGCAAGCTGCCCGAG
GCGCGCTTCGCCTTCATGTCGGCCGAGAACACGCCGGAAATCGTCGCGAAAGCACAGGCGCTGGGCGCCATCGGGTTCAT
CGGCAAGCACGCCGACGCACACGCGTTCTCGCAGGCGGTGGCGGGCATTTTCGGCGGGGACTCGTCGTTCCCGTCGGAAG
ACGACCTGGGCATGGCCAACGGCAAGAACGGCGCCTCCCACGGCATCCCCATCACGCCGGCCGAACTGGGCCTGACGCCG
CGCCAGGGTTCGGTGCTGGCACTGCTGCTCGAAGGGTTGCCGAACAAATCCATCGCGCGCCAACTGGGCCTGACGGAGAA
CACCGTCAAGGAACACGTCTCGGCGATCCTGCAGCGGCTGGGCGTGCGCACGCGCATCCAGATCATCTCGCGCATGGAGC
GCTTCCGCCTGACCGGCTCGGCCTGA

Upstream 100 bases:

>100_bases
TGACCGTGACGGCCATCGGCACCAAGCCCGATGGCCACCGCCCACGCCGGGGCAGCACGCGTACAACAACAAGAGGGCCC
TGCCCTCACCGGGGAATAGA

Downstream 100 bases:

>100_bases
CGCAGGCGCCGCCGCCCGCTGCGGCGCCACTCACACGCATTCCTTCCCTTCAATAAGCCGCCACTTGCGGCTCGGCTGCG
CGGCCGCGCAGCCAGCGCTT

Product: response regulator VSRC transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTSSLRSLLVVDDHPLALSGTTTFLAQALPEIQVHAAIGRRQALALIDEGIRPDVVLLDVWLSDCTGFDAMRELRGKLPE
ARFAFMSAENTPEIVAKAQALGAIGFIGKHADAHAFSQAVAGIFGGDSSFPSEDDLGMANGKNGASHGIPITPAELGLTP
RQGSVLALLLEGLPNKSIARQLGLTENTVKEHVSAILQRLGVRTRIQIISRMERFRLTGSA

Sequences:

>Translated_221_residues
MTSSLRSLLVVDDHPLALSGTTTFLAQALPEIQVHAAIGRRQALALIDEGIRPDVVLLDVWLSDCTGFDAMRELRGKLPE
ARFAFMSAENTPEIVAKAQALGAIGFIGKHADAHAFSQAVAGIFGGDSSFPSEDDLGMANGKNGASHGIPITPAELGLTP
RQGSVLALLLEGLPNKSIARQLGLTENTVKEHVSAILQRLGVRTRIQIISRMERFRLTGSA
>Mature_220_residues
TSSLRSLLVVDDHPLALSGTTTFLAQALPEIQVHAAIGRRQALALIDEGIRPDVVLLDVWLSDCTGFDAMRELRGKLPEA
RFAFMSAENTPEIVAKAQALGAIGFIGKHADAHAFSQAVAGIFGGDSSFPSEDDLGMANGKNGASHGIPITPAELGLTPR
QGSVLALLLEGLPNKSIARQLGLTENTVKEHVSAILQRLGVRTRIQIISRMERFRLTGSA

Specific function: Member of the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hy

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=213, Percent_Identity=26.7605633802817, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788521, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=29.126213592233, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787473, Length=206, Percent_Identity=30.5825242718447, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23512; Mature: 23381

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSLRSLLVVDDHPLALSGTTTFLAQALPEIQVHAAIGRRQALALIDEGIRPDVVLLDV
CCCCCCEEEEECCCCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
WLSDCTGFDAMRELRGKLPEARFAFMSAENTPEIVAKAQALGAIGFIGKHADAHAFSQAV
HHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGIFGGDSSFPSEDDLGMANGKNGASHGIPITPAELGLTPRQGSVLALLLEGLPNKSIAR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHHH
QLGLTENTVKEHVSAILQRLGVRTRIQIISRMERFRLTGSA
HHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSSLRSLLVVDDHPLALSGTTTFLAQALPEIQVHAAIGRRQALALIDEGIRPDVVLLDV
CCCCCEEEEECCCCCEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
WLSDCTGFDAMRELRGKLPEARFAFMSAENTPEIVAKAQALGAIGFIGKHADAHAFSQAV
HHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGIFGGDSSFPSEDDLGMANGKNGASHGIPITPAELGLTPRQGSVLALLLEGLPNKSIAR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHHH
QLGLTENTVKEHVSAILQRLGVRTRIQIISRMERFRLTGSA
HHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]