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The map label for this gene is rsmB [H]

Identifier: 17547172

GI number: 17547172

Start: 2658999

End: 2660252

Strand: Reverse

Name: rsmB [H]

Synonym: RSc2453

Alternate gene names: 17547172

Gene position: 2660252-2658999 (Counterclockwise)

Preceding gene: 17547173

Following gene: 17547171

Centisome position: 71.58

GC content: 68.66

Gene sequence:

>1254_bases
GTGCACGTTAGCCATCTCGAGCATCTCGACAAGGTACTGGCCCGGCTGCTTCATTTTGCCGCACCGGCCGACATGATCGT
CAGCCAGTATTTCCGCGAACACCACGAGCTGGGCCATCGCGAGCGGGGCATCATCGCGGAAGCGGCCTTTGCCGTTCTGC
GGCGCAAGGTCGAGTTCGGGCAGTTTGCCGAGAGCGGTTCCGGCCCGGCGCGCCGGCGCCTGGTGCTGCTGGGCCTGCTG
CAGACCGCCGGCCGCGAGGCCATCGCGCCGTTCCTGACTCCGCAGGAAGCCGAGTGGCTGGACCGCTGGGCGATCATCGA
CCGTACCGCGCTGGCGCCTCGCGTGCGCGCCAATCTGCCGGACTGGCTGTTCGACGCGCTGGTTGCGCAGCACGGCCAGG
CCTTCACCGAGACGTTGGCCCAGGCCTGGCTTGCGCCGGCGCCGCTGGATCTGCGCGTCAACACCCTGAAGGGCGAGCGC
GACGCCGTCCTGGCGACGCTGGCGCAAGCCGGCATCGAGGGCGCGCCGGCGCCGCTGTCGCCGGTCGGCATCCGCCTTGC
GGGCAAGCCGGCACTGAACAAACTCGACATCTTCACCAACGGCACGGTCGAGGTGCAGGACGAAGGGAGCCAGCTCCTGT
GCCAGCTGCTCGCGCCCAAGCGCAGCGAGATGGTGGTCGACTTCTGTGCGGGCGCCGGCGGCAAGACGCTCGCGATCGGT
GCCGCGATGCGCTCCACCGGTCGGCTGTACGCCTTCGATATCTCGGAGAAGCGGCTGGCCAATCTGGGGCCTCGTTTGGC
GCGCAGTGGCCTGTCCAACGTGCATCCGGCCCGCATCGACAGCGAGCATGACGCGAAGGTCAAGCGCCTGGCCGGCAAGA
TCGACCGTGTGCTGGTCGACGCGCCTTGCAGCGGGCTGGGTACGCTGCGCCGCAATCCGGATCTGAAATGGCGTCAGTCG
GCCCAGGCGGTGGAAGAGATGTCGGCCAAGCAGCTGTCGATCCTGGCCTCGGCGGCGCGGCTGCTGAAGGCGGGCGGGCG
GCTGGTCTACGCCACGTGCAGCGTGCTGGCGCGCGAGAACCAGCAGGTGGTCGAACAGTTCCTGGCCCAGCATGCGGATT
TCGTCCTCGTGCCAGCCGGGGAAGCGCTCGCGGCCCAGAAGATTCCGCTCGAAATGGGCCCGTACCTCGAGCTGTATCCG
CATGTCCACCAGACCGACGGCTTCTTCGCCGCCGTGCTGGAACGCCGCGCATGA

Upstream 100 bases:

>100_bases
CCCTGCGGCAGGTAAGCCCCGCGACGGGCGTCCTCAGCGTCCGGCGGGTCGTGCTCCGCAGGGGCAGCGTCCCCAGGCTG
CGCCGCGCTCCCGCACCGGC

Downstream 100 bases:

>100_bases
GGACGCGCGGGCTCGGCCTGGCGCTGGCCGCGTGGCTGGCGCTCGCCGGCGGCGGCACCGCGCTGGCCCGCGTCGAGCCG
CCGGTGCTGCCCGCCAAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MHVSHLEHLDKVLARLLHFAAPADMIVSQYFREHHELGHRERGIIAEAAFAVLRRKVEFGQFAESGSGPARRRLVLLGLL
QTAGREAIAPFLTPQEAEWLDRWAIIDRTALAPRVRANLPDWLFDALVAQHGQAFTETLAQAWLAPAPLDLRVNTLKGER
DAVLATLAQAGIEGAPAPLSPVGIRLAGKPALNKLDIFTNGTVEVQDEGSQLLCQLLAPKRSEMVVDFCAGAGGKTLAIG
AAMRSTGRLYAFDISEKRLANLGPRLARSGLSNVHPARIDSEHDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQS
AQAVEEMSAKQLSILASAARLLKAGGRLVYATCSVLARENQQVVEQFLAQHADFVLVPAGEALAAQKIPLEMGPYLELYP
HVHQTDGFFAAVLERRA

Sequences:

>Translated_417_residues
MHVSHLEHLDKVLARLLHFAAPADMIVSQYFREHHELGHRERGIIAEAAFAVLRRKVEFGQFAESGSGPARRRLVLLGLL
QTAGREAIAPFLTPQEAEWLDRWAIIDRTALAPRVRANLPDWLFDALVAQHGQAFTETLAQAWLAPAPLDLRVNTLKGER
DAVLATLAQAGIEGAPAPLSPVGIRLAGKPALNKLDIFTNGTVEVQDEGSQLLCQLLAPKRSEMVVDFCAGAGGKTLAIG
AAMRSTGRLYAFDISEKRLANLGPRLARSGLSNVHPARIDSEHDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQS
AQAVEEMSAKQLSILASAARLLKAGGRLVYATCSVLARENQQVVEQFLAQHADFVLVPAGEALAAQKIPLEMGPYLELYP
HVHQTDGFFAAVLERRA
>Mature_417_residues
MHVSHLEHLDKVLARLLHFAAPADMIVSQYFREHHELGHRERGIIAEAAFAVLRRKVEFGQFAESGSGPARRRLVLLGLL
QTAGREAIAPFLTPQEAEWLDRWAIIDRTALAPRVRANLPDWLFDALVAQHGQAFTETLAQAWLAPAPLDLRVNTLKGER
DAVLATLAQAGIEGAPAPLSPVGIRLAGKPALNKLDIFTNGTVEVQDEGSQLLCQLLAPKRSEMVVDFCAGAGGKTLAIG
AAMRSTGRLYAFDISEKRLANLGPRLARSGLSNVHPARIDSEHDAKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQS
AQAVEEMSAKQLSILASAARLLKAGGRLVYATCSVLARENQQVVEQFLAQHADFVLVPAGEALAAQKIPLEMGPYLELYP
HVHQTDGFFAAVLERRA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=295, Percent_Identity=30.5084745762712, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI76150623, Length=295, Percent_Identity=30.5084745762712, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI8922322, Length=291, Percent_Identity=29.2096219931272, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI23199998, Length=291, Percent_Identity=29.2096219931272, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI270288816, Length=291, Percent_Identity=29.2096219931272, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI270288818, Length=291, Percent_Identity=29.2096219931272, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI32698918, Length=170, Percent_Identity=30, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI39995082, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI301336155, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=304, Percent_Identity=33.2236842105263, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081985, Length=307, Percent_Identity=30.2931596091205, Blast_Score=111, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17536757, Length=289, Percent_Identity=31.4878892733564, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115534021, Length=224, Percent_Identity=31.25, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=224, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25143471, Length=212, Percent_Identity=31.1320754716981, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=282, Percent_Identity=29.7872340425532, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6319447, Length=267, Percent_Identity=28.4644194756554, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024126, Length=287, Percent_Identity=30.6620209059233, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355201, Length=284, Percent_Identity=30.2816901408451, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356579, Length=219, Percent_Identity=27.8538812785388, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24668781, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356513, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 45414; Mature: 45414

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSHLEHLDKVLARLLHFAAPADMIVSQYFREHHELGHRERGIIAEAAFAVLRRKVEFG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHH
QFAESGSGPARRRLVLLGLLQTAGREAIAPFLTPQEAEWLDRWAIIDRTALAPRVRANLP
HHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCH
DWLFDALVAQHGQAFTETLAQAWLAPAPLDLRVNTLKGERDAVLATLAQAGIEGAPAPLS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
PVGIRLAGKPALNKLDIFTNGTVEVQDEGSQLLCQLLAPKRSEMVVDFCAGAGGKTLAIG
CCCEEEECCCCCCEEEEEECCEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEH
AAMRSTGRLYAFDISEKRLANLGPRLARSGLSNVHPARIDSEHDAKVKRLAGKIDRVLVD
HHHHCCCCEEEEECCHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
APCSGLGTLRRNPDLKWRQSAQAVEEMSAKQLSILASAARLLKAGGRLVYATCSVLAREN
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
QQVVEQFLAQHADFVLVPAGEALAAQKIPLEMGPYLELYPHVHQTDGFFAAVLERRA
HHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MHVSHLEHLDKVLARLLHFAAPADMIVSQYFREHHELGHRERGIIAEAAFAVLRRKVEFG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHH
QFAESGSGPARRRLVLLGLLQTAGREAIAPFLTPQEAEWLDRWAIIDRTALAPRVRANLP
HHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCH
DWLFDALVAQHGQAFTETLAQAWLAPAPLDLRVNTLKGERDAVLATLAQAGIEGAPAPLS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
PVGIRLAGKPALNKLDIFTNGTVEVQDEGSQLLCQLLAPKRSEMVVDFCAGAGGKTLAIG
CCCEEEECCCCCCEEEEEECCEEEECCCHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEH
AAMRSTGRLYAFDISEKRLANLGPRLARSGLSNVHPARIDSEHDAKVKRLAGKIDRVLVD
HHHHCCCCEEEEECCHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
APCSGLGTLRRNPDLKWRQSAQAVEEMSAKQLSILASAARLLKAGGRLVYATCSVLAREN
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
QQVVEQFLAQHADFVLVPAGEALAAQKIPLEMGPYLELYPHVHQTDGFFAAVLERRA
HHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]