Click here to switch to the map view.

The map label for this gene is tISRso11b [H]

Identifier: 17547127

GI number: 17547127

Start: 2613253

End: 2614089

Strand: Reverse

Name: tISRso11b [H]

Synonym: RSc2408

Alternate gene names: 17547127

Gene position: 2614089-2613253 (Counterclockwise)

Preceding gene: 17547128

Following gene: 17547125

Centisome position: 70.34

GC content: 59.02

Gene sequence:

>837_bases
GTGAGTGCGCTGCGTGAGCGGCATTCATTGTCGAGCTTGCTCAAGGCCGCGAATCTCGCACGCAGCACGTACTACTACCA
GATGGCGACAGGCCAGGCAGAGGATCGTCACGGCGCGCTCAAGGAGCGCATTCAGCACATCTATGCCCAGCACAAGGGCC
GATATGGCTACCGCCGGATCACGGCGACGCTCCGTCGGGCAGGGACGTTGGTGAATCACAAGACCGTACAGCGATTGATG
TCGGCGCTACAGTTGAAGTCACTCGTGCGGCCGAAGAAATACCGCTCTTACCTCGGGCAAGTCGGGCGGGTTGCTCCCAA
TCTGCTACAGTGCGAGTTTGAGGCGAGCAAGCCGAACGAGAAGTGGGTAACGGACGTGACGGAGTTCAACGTCGGCGGCA
AAAAGCTGTACCTGTCGCCCGTCCTGGACCTATACAACGGAGAGATCGTCGCCTGGCAAACCAGTGAACGACCTGATTAC
ACGCTGATCCGGGAGATGCTCGACAAGGCGTTGCGCAAGCTGCGCCCGTGCGAGACGCCGATGCTGCATTCGGATCAAGG
CTGGCCGTATCAAATGGCAGCGTATCGTCGCAAACTGGCCGCGCGAGGCCTGCGCCAGAGCATGTCCCGCAAAGGCAACT
GCCTAGACAATGCGGCAATGGAAAGCTTCTTCGGCACACTCAAGTCAGAGTGCTTCCGGTTAGAGCGCTTCGCGGACATC
GACCAACTGCGACGCGCCATTGCCGAATACATCCGGTACTACAATCACGAGCGCATCAAGATCAAGCTAAAAGGGCTGAG
CCCTGTGCAATACAGGACCCAGCCCTTGGCCGCCTAA

Upstream 100 bases:

>100_bases
AAGAGAACGAGTGTTTGCGCGCGGAGGTGGCGTACCTAAAAAAGTTAGATGCCCTGCTGCGTGCCAAACAGCAGCAGGCA
CCAAAGAAAAAGCGCAAGTC

Downstream 100 bases:

>100_bases
ATTACCCGTCCAACTTTACGGGGTCAGTTCATCCGACGTTAATCGGAGCGGCCTTTTTTGCCTTAGCTGAACGGCATTAA
CCGCTTGCGGTGACTTTTCT

Product: isrso11-transposase orfb protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSALRERHSLSSLLKAANLARSTYYYQMATGQAEDRHGALKERIQHIYAQHKGRYGYRRITATLRRAGTLVNHKTVQRLM
SALQLKSLVRPKKYRSYLGQVGRVAPNLLQCEFEASKPNEKWVTDVTEFNVGGKKLYLSPVLDLYNGEIVAWQTSERPDY
TLIREMLDKALRKLRPCETPMLHSDQGWPYQMAAYRRKLAARGLRQSMSRKGNCLDNAAMESFFGTLKSECFRLERFADI
DQLRRAIAEYIRYYNHERIKIKLKGLSPVQYRTQPLAA

Sequences:

>Translated_278_residues
MSALRERHSLSSLLKAANLARSTYYYQMATGQAEDRHGALKERIQHIYAQHKGRYGYRRITATLRRAGTLVNHKTVQRLM
SALQLKSLVRPKKYRSYLGQVGRVAPNLLQCEFEASKPNEKWVTDVTEFNVGGKKLYLSPVLDLYNGEIVAWQTSERPDY
TLIREMLDKALRKLRPCETPMLHSDQGWPYQMAAYRRKLAARGLRQSMSRKGNCLDNAAMESFFGTLKSECFRLERFADI
DQLRRAIAEYIRYYNHERIKIKLKGLSPVQYRTQPLAA
>Mature_277_residues
SALRERHSLSSLLKAANLARSTYYYQMATGQAEDRHGALKERIQHIYAQHKGRYGYRRITATLRRAGTLVNHKTVQRLMS
ALQLKSLVRPKKYRSYLGQVGRVAPNLLQCEFEASKPNEKWVTDVTEFNVGGKKLYLSPVLDLYNGEIVAWQTSERPDYT
LIREMLDKALRKLRPCETPMLHSDQGWPYQMAAYRRKLAARGLRQSMSRKGNCLDNAAMESFFGTLKSECFRLERFADID
QLRRAIAEYIRYYNHERIKIKLKGLSPVQYRTQPLAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=253, Percent_Identity=29.2490118577075, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=55.1094890510949, Blast_Score=340, Evalue=6e-95,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=34.7517730496454, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=34.7517730496454, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=34.7517730496454, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=34.7517730496454, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=34.7517730496454, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32254; Mature: 32123

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALRERHSLSSLLKAANLARSTYYYQMATGQAEDRHGALKERIQHIYAQHKGRYGYRRI
CCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TATLRRAGTLVNHKTVQRLMSALQLKSLVRPKKYRSYLGQVGRVAPNLLQCEFEASKPNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHEEEECCCCCCC
KWVTDVTEFNVGGKKLYLSPVLDLYNGEIVAWQTSERPDYTLIREMLDKALRKLRPCETP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
MLHSDQGWPYQMAAYRRKLAARGLRQSMSRKGNCLDNAAMESFFGTLKSECFRLERFADI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
DQLRRAIAEYIRYYNHERIKIKLKGLSPVQYRTQPLAA
HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCC
>Mature Secondary Structure 
SALRERHSLSSLLKAANLARSTYYYQMATGQAEDRHGALKERIQHIYAQHKGRYGYRRI
CHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TATLRRAGTLVNHKTVQRLMSALQLKSLVRPKKYRSYLGQVGRVAPNLLQCEFEASKPNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHEEEECCCCCCC
KWVTDVTEFNVGGKKLYLSPVLDLYNGEIVAWQTSERPDYTLIREMLDKALRKLRPCETP
HHHHHHHHCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
MLHSDQGWPYQMAAYRRKLAARGLRQSMSRKGNCLDNAAMESFFGTLKSECFRLERFADI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
DQLRRAIAEYIRYYNHERIKIKLKGLSPVQYRTQPLAA
HHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]