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The map label for this gene is panC [H]

Identifier: 17547106

GI number: 17547106

Start: 2595033

End: 2595884

Strand: Direct

Name: panC [H]

Synonym: RSc2387

Alternate gene names: 17547106

Gene position: 2595033-2595884 (Clockwise)

Preceding gene: 17547105

Following gene: 17547107

Centisome position: 69.83

GC content: 67.25

Gene sequence:

>852_bases
ATGAAAGTCATCTCCTCGATCCAGGAACTGCGCGACCAGCTGCGCGGCCAGAACCGCGTCGCCTTCGTGCCGACCATGGG
CAACCTGCATGAGGGCCACCTGAGCCTGATGCGCCTGGCGCGCCAGCACGGCGACCCGGTGGTCGCGTCGATCTTCGTCA
ACCGGCTGCAGTTCGGCCCCAACGAAGACTTCGACAAATACCCGCGCACGCTGCAGGCAGACATCGAGAAGCTGCAGAAG
GAAGGCGTCTACGTGCTGTTCGCGCCCACCGAGCGCGACATGTACCCCGAGCCGCAGGAATACCGCGTCGAGCCGCCGCA
CGACCTGGGCGACATCCTCGAAGGCGAATTCCGCCCCGGCTTCTTCAAGGGCGTGTGCACGGTGGTGATGAAGCTGTTCT
CGTGCGTGCAGCCGCGCGTGGCGGTGTTCGGCAAGAAGGACTACCAGCAGCTGATGATCGTGCGCCGCATGGCCAACCAG
TTCGCGCTGCCGGTCGACATCATCCCCGCCGAGACGGTGCGCGCCGAGGACGGCCTGGCGCTGTCGTCGCGCAATGCGTA
CCTGTCGAACGAAGAGCGCGCCGAGGCGCCCGAGCTGTATCGCACGCTGGGCCAGGTGCGCCAGACCATGCTGGAAACCG
TGCTGCAGGGCCAGGCCTCGGTCGAGGAAGTCACCGCAAAGGCGCTGGAGCACCTGCGCGGACGCGGCTGGCAGCCCGAC
TACGTGGCCGTGCGCCGCCGCTCCGACCTGCAGCCGCCGACGCCCGAGAACATCGCCGCCGGCGAACCGCTGGTGGTGCT
GACCGCCGCCAAGCTCGGCAAGACGCGCCTGATCGACAACCTGGAAATCTGA

Upstream 100 bases:

>100_bases
AGGCCGAACCCTACGCGCCGATCTACGTGCGGCTGGCCTATTCCCCGACCTGATCCCCCTGACCTGATCCGCCGGGTCTG
CCGGACTCCAACAAGAACGC

Downstream 100 bases:

>100_bases
ATTCAGATTTGCTGAATTGAGAACAACCTAGCTCCACGTAAAATCAAACGCTGCATTTTACCTGGAGCTCTGCGTGTTCT
ATTGCAGCTTTGAACTCAAC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQADIEKLQK
EGVYVLFAPTERDMYPEPQEYRVEPPHDLGDILEGEFRPGFFKGVCTVVMKLFSCVQPRVAVFGKKDYQQLMIVRRMANQ
FALPVDIIPAETVRAEDGLALSSRNAYLSNEERAEAPELYRTLGQVRQTMLETVLQGQASVEEVTAKALEHLRGRGWQPD
YVAVRRRSDLQPPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI

Sequences:

>Translated_283_residues
MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQADIEKLQK
EGVYVLFAPTERDMYPEPQEYRVEPPHDLGDILEGEFRPGFFKGVCTVVMKLFSCVQPRVAVFGKKDYQQLMIVRRMANQ
FALPVDIIPAETVRAEDGLALSSRNAYLSNEERAEAPELYRTLGQVRQTMLETVLQGQASVEEVTAKALEHLRGRGWQPD
YVAVRRRSDLQPPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI
>Mature_283_residues
MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQADIEKLQK
EGVYVLFAPTERDMYPEPQEYRVEPPHDLGDILEGEFRPGFFKGVCTVVMKLFSCVQPRVAVFGKKDYQQLMIVRRMANQ
FALPVDIIPAETVRAEDGLALSSRNAYLSNEERAEAPELYRTLGQVRQTMLETVLQGQASVEEVTAKALEHLRGRGWQPD
YVAVRRRSDLQPPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=286, Percent_Identity=42.6573426573427, Blast_Score=216, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=295, Percent_Identity=36.9491525423729, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32009; Mature: 32009

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQADIEKLQKEGVYVLFAPTERDMYPEPQEYRVEPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCH
FFKGVCTVVMKLFSCVQPRVAVFGKKDYQQLMIVRRMANQFALPVDIIPAETVRAEDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHCCCCCCE
LSSRNAYLSNEERAEAPELYRTLGQVRQTMLETVLQGQASVEEVTAKALEHLRGRGWQPD
ECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
YVAVRRRSDLQPPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI
HHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHCHHHHHCCCCC
>Mature Secondary Structure
MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQADIEKLQKEGVYVLFAPTERDMYPEPQEYRVEPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCH
FFKGVCTVVMKLFSCVQPRVAVFGKKDYQQLMIVRRMANQFALPVDIIPAETVRAEDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHCCCCCCE
LSSRNAYLSNEERAEAPELYRTLGQVRQTMLETVLQGQASVEEVTAKALEHLRGRGWQPD
ECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
YVAVRRRSDLQPPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI
HHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA