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The map label for this gene is ppa

Identifier: 17547068

GI number: 17547068

Start: 2548301

End: 2548828

Strand: Reverse

Name: ppa

Synonym: RSc2349

Alternate gene names: 17547068

Gene position: 2548828-2548301 (Counterclockwise)

Preceding gene: 17547074

Following gene: 17547066

Centisome position: 68.58

GC content: 62.5

Gene sequence:

>528_bases
ATGAGCTTCAACAACGTCTCGCCGGGCAAGGACATCCCCAACGACTTCAACGTCATCATCGAGATCCCGGCGCAGAGCGA
CCCGGTCAAGTACGAAGCCGACAAGGAAACCGGCCTGCTGCACGTGGACCGCTTCGTCGGTACCGGCATGCGCTATCCGG
CCAACTACGGCTTCATCCCGCAGACGCTGGCCGGCGACGGCGATCCGGTGGACGTGCTGGTCGTCACGCCGTTCCCGCTG
GTCCACGGCTGCGTGGTGCGTTGCCGCACCCTGGGCATGCTGAAGATGACCGACGAGTCGGGCCAGGACGCCAAGCTGGT
CGCCGTGCCGGTCAACAAGCTGTCGCCGGCCACCGCGCACATGACGGACCTGTCCGACATCGGCCAGAACCTGCTTGACC
AGATCAAGCATTTCTTCGAGCAGTACAAGGCGCTGGAGCCCGGCAAGTGGGTCAAGGTGGAAGGCTGGGGCGGCATCGAG
GAAGCGCATAAAGAAATCGTCGATGGCGTAGCCAACTATAAGAAGTAA

Upstream 100 bases:

>100_bases
ACGGCCGGCCGGGTGCCACCGGCTATAATGCCGGCCGCGAAAAGTTTTCACGCATTCGTTTTTTCAATCCGCTGATTTCA
CGCATTCCGGAGCACTTTCC

Downstream 100 bases:

>100_bases
GCGATTCTCGTTTTTTGTCGTACGGTGTCATCTCGATCATCCCGGCATTCCTTTCGGATTGCCGGGATGTTTTGTTTGAA
TACCAATGGCGCAGCGTGAC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLHVDRFVGTGMRYPANYGFIPQTLAGDGDPVDVLVVTPFPL
VHGCVVRCRTLGMLKMTDESGQDAKLVAVPVNKLSPATAHMTDLSDIGQNLLDQIKHFFEQYKALEPGKWVKVEGWGGIE
EAHKEIVDGVANYKK

Sequences:

>Translated_175_residues
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLHVDRFVGTGMRYPANYGFIPQTLAGDGDPVDVLVVTPFPL
VHGCVVRCRTLGMLKMTDESGQDAKLVAVPVNKLSPATAHMTDLSDIGQNLLDQIKHFFEQYKALEPGKWVKVEGWGGIE
EAHKEIVDGVANYKK
>Mature_174_residues
SFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLHVDRFVGTGMRYPANYGFIPQTLAGDGDPVDVLVVTPFPLV
HGCVVRCRTLGMLKMTDESGQDAKLVAVPVNKLSPATAHMTDLSDIGQNLLDQIKHFFEQYKALEPGKWVKVEGWGGIEE
AHKEIVDGVANYKK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=167, Percent_Identity=62.2754491017964, Blast_Score=213, Evalue=8e-57,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_RALSO (Q8XWX1)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520470.1
- ProteinModelPortal:   Q8XWX1
- SMR:   Q8XWX1
- GeneID:   1221195
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2349
- NMPDR:   fig|267608.1.peg.2349
- HOGENOM:   HBG529150
- OMA:   EHFFEHY
- ProtClustDB:   PRK01250
- BioCyc:   RSOL267608:RSC2349-MONOMER
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19224; Mature: 19093

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLHVDRFVGTGMRYPANYGFIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCC
QTLAGDGDPVDVLVVTPFPLVHGCVVRCRTLGMLKMTDESGQDAKLVAVPVNKLSPATAH
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCHHH
MTDLSDIGQNLLDQIKHFFEQYKALEPGKWVKVEGWGGIEEAHKEIVDGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNNVSPGKDIPNDFNVIIEIPAQSDPVKYEADKETGLLHVDRFVGTGMRYPANYGFIP
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCC
QTLAGDGDPVDVLVVTPFPLVHGCVVRCRTLGMLKMTDESGQDAKLVAVPVNKLSPATAH
HHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCCHHH
MTDLSDIGQNLLDQIKHFFEQYKALEPGKWVKVEGWGGIEEAHKEIVDGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852