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The map label for this gene is yhcZ [H]

Identifier: 17547031

GI number: 17547031

Start: 2512809

End: 2513525

Strand: Reverse

Name: yhcZ [H]

Synonym: RSc2312

Alternate gene names: 17547031

Gene position: 2513525-2512809 (Counterclockwise)

Preceding gene: 17547033

Following gene: 17547029

Centisome position: 67.63

GC content: 62.48

Gene sequence:

>717_bases
GTGAGCACCGTACATCGCCTGTTGATCGCGGAGGATCATCATTTGCTCAGGTGTGGTCTGCGATCCATGTTGTCCGCCCT
GGGTGAATACGACGTGGTCGGGGAAGCAAAGGACGGAAGGGAGGCGTGCCAACTGGCCATCTCGCTGGCCCCGGACCTGG
TGCTGACCGATCTGTCGATGCCCGGCATGAACGGCATCGATATGGTGGCGACGATCAAGCGCCGCCTGCCGCAGATCCGC
GTGGTCGTGCTGACCGTCTACAAGTCGGAAGAGTATGTGAGGGAAGCGCTGCGCGTGGGGGTCGACGGCTATGTCCTGAA
AGATGCGTCGTTCGAGGAACTGGTGGCTGCGCTGCGCGCGGTCATGCAGGGCAAGCGACATCTGAGCGCCGATGTCTATG
GCAACGTGGTCAAGTCGTTTGTCAATGGTCATGAGGCACTGGCGCCCAAGAGCACCTGGGAAACGCTGACCGCGCGCGAG
CGCAGCGTGCTGCAGCTCGTGGCCGAAGGCCGGACCAATCGCCAGGTCGGGCTCTACCTGAACCTCAGTCCCAAGACGAT
CGAGAAATACCGCGCGCACCTGATGGAAAAGCTCGGCGTCGGCAATGTGACCGGGCTGGTGCTTGCCGCGATCGGCCTGG
GCTTGATCGCGCCGCAGTCGGATCTGCAAAGCGACACCAATATCGAGCCCCCGGCGTATCGCCGTGAGGTGAGGTGA

Upstream 100 bases:

>100_bases
CATTCGAACTATGCCGCAGGAATTCCCGTGAGGTTTTGGGACAACGAACACAATTCAGGCGGCCGGTGCGCCCAAGCGGC
CGAACTGAGGAGGAGTCGCC

Downstream 100 bases:

>100_bases
ACGGGCGGCGGCTTGACGGTATTGAGGTCACCGTGGGCGGCTGCCCGTGGTCATGCGCGCCATAGCGCGGAGACCAGCGT
GCCGTCGCCCACGCTCGACT

Product: two-component response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSTVHRLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSMPGMNGIDMVATIKRRLPQIR
VVVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRAVMQGKRHLSADVYGNVVKSFVNGHEALAPKSTWETLTARE
RSVLQLVAEGRTNRQVGLYLNLSPKTIEKYRAHLMEKLGVGNVTGLVLAAIGLGLIAPQSDLQSDTNIEPPAYRREVR

Sequences:

>Translated_238_residues
MSTVHRLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSMPGMNGIDMVATIKRRLPQIR
VVVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRAVMQGKRHLSADVYGNVVKSFVNGHEALAPKSTWETLTARE
RSVLQLVAEGRTNRQVGLYLNLSPKTIEKYRAHLMEKLGVGNVTGLVLAAIGLGLIAPQSDLQSDTNIEPPAYRREVR
>Mature_237_residues
STVHRLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSMPGMNGIDMVATIKRRLPQIRV
VVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRAVMQGKRHLSADVYGNVVKSFVNGHEALAPKSTWETLTARER
SVLQLVAEGRTNRQVGLYLNLSPKTIEKYRAHLMEKLGVGNVTGLVLAAIGLGLIAPQSDLQSDTNIEPPAYRREVR

Specific function: Member of the two-component regulatory system yhcY/yhcZ [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=31.1004784688995, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=34, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=35.8695652173913, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=31.7708333333333, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=31.219512195122, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=25.6544502617801, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=21.3930348258706, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=36.2745098039216, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=156, Percent_Identity=29.4871794871795, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26187; Mature: 26056

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVHRLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSM
CCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCC
PGMNGIDMVATIKRRLPQIRVVVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRA
CCCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHH
VMQGKRHLSADVYGNVVKSFVNGHEALAPKSTWETLTARERSVLQLVAEGRTNRQVGLYL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
NLSPKTIEKYRAHLMEKLGVGNVTGLVLAAIGLGLIAPQSDLQSDTNIEPPAYRREVR
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
STVHRLLIAEDHHLLRCGLRSMLSALGEYDVVGEAKDGREACQLAISLAPDLVLTDLSM
CHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCC
PGMNGIDMVATIKRRLPQIRVVVLTVYKSEEYVREALRVGVDGYVLKDASFEELVAALRA
CCCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHH
VMQGKRHLSADVYGNVVKSFVNGHEALAPKSTWETLTARERSVLQLVAEGRTNRQVGLYL
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
NLSPKTIEKYRAHLMEKLGVGNVTGLVLAAIGLGLIAPQSDLQSDTNIEPPAYRREVR
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]