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The map label for this gene is pilC [H]

Identifier: 17547028

GI number: 17547028

Start: 2509561

End: 2510763

Strand: Reverse

Name: pilC [H]

Synonym: RSc2309

Alternate gene names: 17547028

Gene position: 2510763-2509561 (Counterclockwise)

Preceding gene: 17547029

Following gene: 17547027

Centisome position: 67.56

GC content: 69.66

Gene sequence:

>1203_bases
GTGAAGTACTTGCTGCGAGTCTTCGATTCCGGTGGCCTGGTGCAGACGGTCTGCATCGAGGGCGACACGCCGGCCGGCGC
GACCGCGGCAGCGCACGCACGGGGCTGGAAGGTGATCGCGGTCCGGGCCGGCGGCGCGCGCGGCCGGCACCGCATCCGCG
GCACGGTGCTGGGAGGGACGGCATTCGACGTCGAACTGTTCGCGCGCGAGCTCGCGGCGCTGCTCGATGCGGGCGTGAGC
GTCATCGATGCGCTGCGCACGCTCGGCAGCAACGAACGCCGGGAGGCATCGGCGGCGGTCTATCGCGATCTGCTGCGGCG
CCTGGAGGAAGGCCACGCGCTGTCGGCGGCCCTGGAGCTGGCGGACAACGTCTTCCCGCCCGTGCTGGTGGCCTGCGTCA
AGGCCAGCGAGCAGACGGGCGGCCTTGCCGCCAGCCTGAAGCGCTATTCGCAGAACAGCGCGACGCTGCAGGCCTTGCGT
GCCCGCGTGGTGTCCGCGTCGATCTATCCCGCCGTGCTGCTTGCCGTGGGAGGCTCGGTTGCCGTGTTCCTGCTCGCGTT
CGTGGTGCCCCGCTTCGCCGGGCTGCTGGAGCACAGCGGGCGCGAGCTGCCGATGCTGTCTCAATGGCTGATGGCCTGGG
GCGCGATGGTGCATGCGCATGGCCAGGGCCTCGCCGTCGGGTTTGCCATCTGTGTGCTGGCCGGAATCGGCGCGTTGCGT
CGCCAGGCGACGCGCAGCTGGGCCACCGATCGGCTGCTCTCCCTGCCGGGAGTCGGCGAGCATTTCCGTGTCTACCGGCA
GGCACAGTTCTTCCGCACGTCGGCCATGCTGGTCGATGGCGGCATCCCGGCCGTGCAGGCGTTCGATCTGGCGTGCGGAC
TGGTCAGCCGCGCGGATCGCGCCGCGCTGGCGTCGGCCATGGAGCGCATTCGCAATGGCGGCAGGATGTCCGATGCGTTT
CTCGGCAGCGGGCTGGCCGACCCGATCACCTACCGGCTGCTGACGGTCGCCGAGAAGACGGGTGGGCTGGGGCCGGTGCT
CGACAAGATCGCCGCCTTTCAGGAAGCGCACGTCTCCCATGCGATCGACCTGGCGTCACGGCTGGTCGAACCCGCCATGA
TGATGGTGATCGGCGTCGTGATCGGCGGCATCGTCGTGCTGATGTACCTGCCGATCTTTCAACTGGCGTCGAGCGTCCAG
TAG

Upstream 100 bases:

>100_bases
CAGCCCGGCGGCACCGGCGAGAACGTGGCGGTCACATCGTGGTGAAGGCGCGGACCGGCTGGCCGTGAAGCCTGCGGCCG
GGCCGTTAGAGGGGGCTGAG

Downstream 100 bases:

>100_bases
GTGCGCCATGGACACGAACTGCGCAACCCCCGACTCGCGCGGCACCCTGTACCGCGATGCCTTGCGCGAACTCGGCGAGC
GCTACGGCTCGGGCATCCGG

Product: GSPF-related transmembrane protein

Products: NA

Alternate protein names: Type IV-A pilus assembly protein pilC [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKYLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVLGGTAFDVELFARELAALLDAGVS
VIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAALELADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALR
ARVVSASIYPAVLLAVGGSVAVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIGALR
RQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVSRADRAALASAMERIRNGGRMSDAF
LGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEAHVSHAIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSVQ

Sequences:

>Translated_400_residues
MKYLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVLGGTAFDVELFARELAALLDAGVS
VIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAALELADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALR
ARVVSASIYPAVLLAVGGSVAVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIGALR
RQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVSRADRAALASAMERIRNGGRMSDAF
LGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEAHVSHAIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSVQ
>Mature_400_residues
MKYLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVLGGTAFDVELFARELAALLDAGVS
VIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAALELADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALR
ARVVSASIYPAVLLAVGGSVAVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIGALR
RQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVSRADRAALASAMERIRNGGRMSDAF
LGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEAHVSHAIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSVQ

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=401, Percent_Identity=24.1895261845387, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786295, Length=339, Percent_Identity=29.4985250737463, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42234; Mature: 42234

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVLGGT
CCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCCHHEEEEEECCC
AFDVELFARELAALLDAGVSVIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAALEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALRARVVSASIYPAVLLAVGGSV
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIGALR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVSRADR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
AALASAMERIRNGGRMSDAFLGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEAHVSH
HHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYLLRVFDSGGLVQTVCIEGDTPAGATAAAHARGWKVIAVRAGGARGRHRIRGTVLGGT
CCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCCHHEEEEEECCC
AFDVELFARELAALLDAGVSVIDALRTLGSNERREASAAVYRDLLRRLEEGHALSAALEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ADNVFPPVLVACVKASEQTGGLAASLKRYSQNSATLQALRARVVSASIYPAVLLAVGGSV
HHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AVFLLAFVVPRFAGLLEHSGRELPMLSQWLMAWGAMVHAHGQGLAVGFAICVLAGIGALR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RQATRSWATDRLLSLPGVGEHFRVYRQAQFFRTSAMLVDGGIPAVQAFDLACGLVSRADR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHH
AALASAMERIRNGGRMSDAFLGSGLADPITYRLLTVAEKTGGLGPVLDKIAAFQEAHVSH
HHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AIDLASRLVEPAMMMVIGVVIGGIVVLMYLPIFQLASSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10024587; 10952301 [H]